Protein Overview: AT2B1_RAT

General Information:
Name(s) found:	AT2B1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|14286099\|sp\|P11505.2\|AT2B1_RAT RecName: Full=Plasma membrane calcium-transporting ATPase 1; Short=PMCA1; AltName: Full=Plasma membrane calcium ATPase isoform 1; AltName: Full=Plasma membrane calcium pump isoform 1 [NCBI NR] (P11505) Plasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1) (Plasma membrane calcium pump isoform 1) (Plasma membrane calcium ATPase isoform 1) [Swiss-Prot] Plasma membrane calcium-transporting ATPase 1 OS=Rattus norvegicus GN=Atp2b1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform D of P11505 [hmr_yeast5_DM3-1_pombe.fasta] Plasma membrane calcium-transporting ATPase 1 (PMCA1) (Plasma membrane calcium pump isoform 1) (Plasma membrane calcium ATPase isoform 1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform D of Plasma membrane calcium-transporting ATPase 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Plasma membrane calcium-transporting ATPase 1 (PMCA1) (Plasma membrane calcium ATPase isoform 1) (Plasma membrane calcium pump isoform 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Atp2b1 Isoform D of Plasma membrane calcium-transporting ATPase 1 [rat-ipi-250309-contam.fasta] Isoform D of Plasma membrane calcium-transporting ATPase 1 OS=Rattus norvegicus GN=Atp2b1 [011711_HMR.fasta] Plasma membrane calcium-transporting ATPase 1 OS=Rattus norvegicus GN=Atp2b1 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1258 amino acids
Gene Ontology:
Cellular Component:	apical part of cell [IDA] membrane [IEA] membrane raft [IDA] integral to membrane [IEA] plasma membrane [IEA] apical plasma membrane [IDA]
Biological Process:	response to cold [IEP] cation transport [IEA] neural retina development [IEP] calcium ion transport [IEA] metabolic process [IEA] negative regulation of smooth muscle cell proliferation [IMP] cellular response to corticosterone stimulus [IEP] calcium ion transmembrane transport [IMP] brain development [IEP] ATP biosynthetic process [IEA] aging [IEP] cellular response to vitamin D [IEP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] calmodulin binding [IEA] protein binding [UNKNOWN] catalytic activity [IEA] metal ion binding [IEA] PDZ domain binding [IPI] calcium-transporting ATPase activity [IEA] hydrolase activity [IEA] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDMANNSVA YSGVKNSLKE ANHDGDFGIT LAELRALMEL RSTDALRKIQ ESYGDVYGIC  60
   61 TKLKTSPNEG LSGNPADLER REAVFGKNFI PPKKPKTFLQ LVWEALQDVT LIILEIAAIV 120
  121 SLGLSFYQPP EGDNALCGEV SVGEEEGEGE TGWIEGAAIL LSVVCVVLVT AFNDWSKEKQ 180
  181 FRGLQSRIEQ EQKFTVIRGG QVIQIPVADI TVGDIAQVKY GDLLPADGIL IQGNDLKIDE 240
  241 SSLTGESDHV KKSLDKDPLL LSGTHVMEGS GRMVVTAVGV NSQTGIIFTL LGAGGEEEEK 300
  301 KDEKKKEKKN KKQDGAIENR NKAKAQDGAA MEMQPLKSEE GGDGDEKDKK KANLPKKEKS 360
  361 VLQGKLTKLA VQIGKAGLLM SAITVIILVL YFVIDTFWVQ KRPWLAECTP IYIQYFVKFF 420
  421 IIGVTVLVVA VPEGLPLAVT ISLAYSVKKM MKDNNLVRHL DACETMGNAT AICSDKTGTL 480
  481 TMNRMTVVQA YINEKHYKKV PEPEAIPPNI LSYLVTGISV NCAYTSKILP PEKEGGLPRH 540
  541 VGNKTECALL GFLLDLKRDY QDVRNEIPEE ALYKVYTFNS VRKSMSTVLK NSDGSFRIFS 600
  601 KGASEIILKK CFKILSANGE AKVFRPRDRD DIVKTVIEPM ASEGLRTICL AFRDFPAGEP 660
  661 EPEWDNENDV VTGLTCIAVV GIEDPVRPEV PEAIKKCQRA GITVRMVTGD NINTARAIAT 720
  721 KCGILHPGED FLCLEGKDFN RRIRNEKGEI EQERIDKIWP KLRVLARSSP TDKHTLVKGI 780
  781 IDSTVSEQRQ VVAVTGDGTN DGPALKKADV GFAMGIAGTD VAKEASDIIL TDDNFTSIVK 840
  841 AVMWGRNVYD SISKFLQFQL TVNVVAVIVA FTGACITQDS PLKAVQMLWV NLIMDTLASL 900
  901 ALATEPPTES LLLRKPYGRN KPLISRTMMK NILGHAFYQL VVVFTLLFAG EKFFDIDSGR 960
  961 NAPLHAPPSE HYTIVFNTFV LMQLFNEINA RKIHGERNVF EGIFNNAIFC TIVLGTFVVQ1020
 1021 IIIVQFGGKP FSCSELSIEQ WLWSIFLGMG TLLWGQLIST IPTSRLKFLK EAGHGTQKEE1080
 1081 IPEEELAEDV EEIDHAEREL RRGQILWFRG LNRIQTQMDV VNAFQSGGSI QGALRRQPSI1140
 1141 ASQHHDVTNV STPTHIRVVN AFRSSLYEGL EKPESRSSIH NFMTHPEFRI EDSEPLIPLI1200
 1201 DDTDAEDDAP TKRNSSPPPS PNKNNNAVDS GIHLTIEMNK SATSSSPGSP LHSLETSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AT2B1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: