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Protein Overview: CDK4_RAT

General Information:
Name(s) found: CDK4_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Cyclin-dependent kinase 4 OS=Rattus norvegicus GN=Cdk4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 303 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    transcription factor complex [UNKNOWN]
    perinuclear region of cytoplasm [IDA]
    cytoplasm [IDA]
    cyclin-dependent protein kinase holoenzyme complex [UNKNOWN]
    cytosol [UNKNOWN]
    nucleoplasm [UNKNOWN]
    Biological Process: response to hyperoxia [IEP]
    response to organic substance [IMP]
    positive regulation of translation [IMP]
    signal transduction [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN][IMP]
    positive regulation of cell cycle [TAS]
    protein amino acid phosphorylation [UNKNOWN][IEA]
    circadian rhythm [IEP]
    response to toxin [IEP]
    regulation of cell proliferation [UNKNOWN]
    cell division [IEA]
    positive regulation of cell size [IMP]
    positive regulation of fibroblast proliferation [UNKNOWN]
    G1/S transition of mitotic cell cycle [UNKNOWN]
    positive regulation of apoptosis [IMP]
    regulation of gene expression [UNKNOWN]
    organ regeneration [IEP]
    response to testosterone stimulus [IDA]
    regulation of cell cycle [UNKNOWN][TAS]
    response to lead ion [IMP]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN][IDA]
    protein kinase activity [UNKNOWN]
    cyclin-dependent protein kinase activity [UNKNOWN][IDA]
    transferase activity [IEA]
    protein complex binding [IPI]
    kinase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTRYEPVA EIGVGAYGTV YKARDPHSGH FVALKSVRVP NGGAAGGGLP VSTVREVALL  60
   61 RRLEAFEHPN VVRLMDVCAT SRTDRDIKVT LVFEHIDQDL RTYLDKAPPP GLPVETIKDL 120
  121 MRQFLSGLDF LHANCIVHRD LKPENILVTS NGTVKLADFG LARIYSYQMA LTPVVVTLWY 180
  181 RAPEVLLQST YATPVDMWSV GCIFAEMFRR KPLFCGNSEA DQLGKIFDLI GLPPEDDWPR 240
  241 EVSLPRGAFS PRGPRPVQSV VPEMEESGAQ LLLEMLTFNP LKRISAFRAL QHSYLHKEES 300
  301 DPE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle