Protein Overview: ANPRA_RAT

General Information:
Name(s) found:	ANPRA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981280\|ref\|NP_036745.1\| natriuretic peptide receptor 1 [Rattus norvegicus] [NCBI NR] pir\|\|OYRTR atrial natriuretic peptide receptor A precursor - rat [NCBI NR] gi\|56340\|emb\|CAA32881.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|226288\|prf\|\|1505371A membrane guanylate cyclase [NCBI NR] gi\|149047993\|gb\|EDM00569.1\| natriuretic peptide receptor 1, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149047992\|gb\|EDM00568.1\| natriuretic peptide receptor 1, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|118763763\|gb\|AAI28743.1\| Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [Rattus norvegicus] [NCBI NR] gi\|113915\|sp\|P18910.1\|ANPRA_RAT RecName: Full=Atrial natriuretic peptide receptor A; AltName: Full=Atrial natriuretic peptide A-type receptor; AltName: Full=ANPRA; AltName: Full=ANP-A; AltName: Full=NPR-A; AltName: Full=Guanylate cyclase; Short=GC-A; Flag [NCBI NR] Atrial natriuretic peptide receptor 1 OS=Rattus norvegicus GN=Npr1 PE=1 SV=1 [Swiss-Prot] (P18910) Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) [Swiss-Prot] Ensembl_locations(Chr-bp):2-179025308 Atrial natriuretic peptide receptor A precursor [hmr_yeast5_DM3-1_pombe.fasta] natriuretic peptide receptor 1; natriuretic peptide receptor A/Guanylate cyclase A [HMR_022704-rand.fasta] natriuretic peptide receptor 1 [Rattus norvegicus]gi\|56340\|emb\|CAA32881.1\| unnamed protein product [Rattus norvegicus]gi\|68382\|pir\|\|OYRTR atrial natriuretic peptide receptor A precursor - ratgi\|2144077\|pir\|\|I55319 guanylyl cyclase A/atrial natriuretic [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Atrial natriuretic peptide receptor A precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012613) natriuretic peptide receptor 1; Natriuretic peptide receptor A/Guanylate cyclase A [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Atrial natriuretic peptide receptor A precursor (Atrial natriuretic peptide A-type receptor) (ANPRA) (ANP-A) (NPR-A) (Guanylate cyclase) (GC-A) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] natriuretic peptide receptor 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] natriuretic peptide receptor 1, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Natriuretic peptide receptor 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] membrane guanylate cyclase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ATRIAL NATRIURETIC PEPTIDE RECEPTOR A PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (NPR-A) (Atrial natriuretic peptide A-type receptor) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Npr1 Atrial natriuretic peptide receptor A [rat-ipi-250309-contam.fasta] Atrial natriuretic peptide receptor 1 OS=Rattus norvegicus GN=Npr1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1057 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] cellular_component [ND] plasma membrane [IDA]
Biological Process:	cGMP biosynthetic process [UNKNOWN][IDA] dopamine metabolic process [IMP] intracellular signaling pathway [IDA] regulation of blood vessel size [IEA] positive regulation of cGMP biosynthetic process [IMP] negative regulation of smooth muscle cell proliferation [IMP] receptor guanylyl cyclase signaling pathway [UNKNOWN] cell surface receptor linked signaling pathway [IMP] protein amino acid phosphorylation [IEA] [NOT]regulation of blood pressure [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] GTP binding [IDA] ATP binding [IEA] protein kinase binding [IMP] peptide receptor activity, G-protein coupled [IEA] guanylate cyclase activity [UNKNOWN][IDA] hormone binding [UNKNOWN] protein kinase activity [IEA] peptide hormone binding [IDA] receptor activity [IEA] natriuretic peptide receptor activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGSRRVRPR LRALLLLPPL LLLRGGHASD LTVAVVLPLT NTSYPWSWAR VGPAVELALA  60
   61 RVKARPDLLP GWTVRMVLGS SENAAGVCSD TAAPLAAVDL KWEHSPAVFL GPGCVYSAAP 120
  121 VGRFTAHWRV PLLTAGAPAL GIGVKDEYAL TTRTGPSHVK LGDFVTALHR RLGWEHQALV 180
  181 LYADRLGDDR PCFFIVEGLY MRVRERLNIT VNHQEFVEGD PDHYPKLLRA VRRKGRVIYI 240
  241 CSSPDAFRNL MLLALNAGLT GEDYVFFHLD VFGQSLKSAQ GLVPQKPWER GDGQDRSARQ 300
  301 AFQAAKIITY KEPDNPEYLE FLKQLKLLAD KKFNFTVEDG LKNIIPASFH DGLLLYVQAV 360
  361 TETLAQGGTV TDGENITQRM WNRSFQGVTG YLKIDRNGDR DTDFSLWDMD PETGAFRVVL 420
  421 NYNGTSQELM AVSEHKLYWP LGYPPPDVPK CGFDNEDPAC NQDHFSTLEV LALVGSLSLI 480
  481 SFLIVSFFIY RKMQLEKELV SELWRVRWED LQPSSLERHL RSAGSRLTLS GRGSNYGSLL 540
  541 TTEGQFQVFA KTAYYKGNLV AVKRVNRKRI ELTRKVLFEL KHMRDVQNEH LTRFVGACTD 600
  601 PPNICILTEY CPRGSLQDIL ENESITLDWM FRYSLTNDIV KGMLFLHNGA ICSHGNLKSS 660
  661 NCVVDGRFVL KITDYGLESF RDPEPEQGHT LFAKKLWTAP ELLRMASPPA RGSQAGDVYS 720
  721 FGIILQEIAL RSGVFYVEGL DLSPKEIIER VTRGEQPPFR PSMDLQSHLE ELGQLMQRCW 780
  781 AEDPQERPPF QQIRLALRKF NKENSSNILD NLLSRMEQYA NNLEELVEER TQAYLEEKRK 840
  841 AEALLYQILP HSVAEQLKRG ETVQAEAFDS VTIYFSDIVG FTALSAESTP MQVVTLLNDL 900
  901 YTCFDAVIDN FDVYKVETIG DAYMVVSGLP VRNGQLHARE VARMALALLD AVRSFRIRHR 960
  961 PQEQLRLRIG IHTGPVCAGV VGLKMPRYCL FGDTVNTASR MESNGEALKI HLSSETKAVL1020
 1021 EEFDGFELEL RGDVEMKGKG KVRTYWLLGE RGCSTRG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ANPRA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: