Protein Overview: CAC1D_RAT

General Information:
Name(s) found:	CAC1D_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393030\|ref\|NP_058994.1\| calcium channel, voltage-dependent, L type, alpha 1D subunit [Rattus norvegicus] [NCBI NR] gi\|736712\|dbj\|BAA07282.1\| L-type voltage-dependent calcium channel alpha 1 subunit [Rattus norvegicus] [NCBI NR] gi\|6165987\|sp\|P27732.2\|CAC1D_RAT RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1D; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.3; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 2; AltName: Ful [NCBI NR] gi\|11279257\|pir\|\|T42742 voltage-dependent calcium channel alpha 1 chain, isoform CACN4A - rat [NCBI NR] (P27732) Voltage-dependent L-type calcium channel alpha-1D subunit (Voltage-gated calcium channel alpha subunit Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (RAT brain class D) (RBD) [Swiss-Prot] Voltage-dependent L-type calcium channel subunit alpha-1D OS=Rattus norvegicus GN=Cacna1d PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):16-5339411 Splice isoform 1 of P27732 [hmr_yeast5_DM3-1_pombe.fasta] calcium channel, voltage-dependent, L type, alpha 1D subunit; CaV1.3alpha1 [HMR_022704-rand.fasta] calcium channel, voltage-dependent, L type, alpha 1D subunit [Rattus norvegicus]gi\|11279257\|pir\|\|T42742 voltage-dependent calcium channel alpha 1 chain, isoform CACN4A - ratgi\|6165987\|sp\|P27732\|CCAD_RAT Voltage-dependent L-type calcium channel alpha-1D [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Voltage-dependent L-type calcium channel alpha-1D subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017298) calcium channel, voltage-dependent, L type, alpha 1D subunit [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage-gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcium channel, voltage-dependent, L type, alpha 1D subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] L-type voltage-dependent calcium channel alpha 1 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] voltage-dependent calcium channel alpha 1 chain, isoform CACN4A - rat [nr-271106-contam.fasta] Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage-gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (RAT brain class D) (RBD) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Cacna1d Isoform 1 of Voltage-dependent L-type calcium channel subunit alpha-1D [rat-ipi-250309-contam.fasta] Isoform 1 of Voltage-dependent L-type calcium channel subunit alpha-1D OS=Rattus norvegicus GN=Cacna1d [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	2203 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] voltage-gated calcium channel complex [UNKNOWN][IEA][TAS] integral to membrane [IEA] plasma membrane [UNKNOWN] apical plasma membrane [IDA]
Biological Process:	sensory perception of sound [UNKNOWN] ion transport [IEA] transmembrane transport [IEA] calcium ion transport [UNKNOWN][IEA] G-protein signaling, coupled to cAMP nucleotide second messenger [UNKNOWN] calcium-mediated signaling [IDA] memory [IEP]
Molecular Function:	ion channel activity [IEA] protein binding [UNKNOWN] high voltage-gated calcium channel activity [UNKNOWN] dihydropyridine-sensitive calcium channel activity [UNKNOWN] voltage-gated calcium channel activity [UNKNOWN][IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMMMMMMKKM QHQRQQQEDH ANEANYARGT RLPISGEGPT SQPNSSKQTV LSWQAAIDAA  60
   61 RQAKAAQTMS TSAPPPVGSL SQRKRQQYAK SKKQGNSSNS RPARALFCLS LNNPIRRACI 120
  121 SIVDWKPFDI FILLAIFANC VALAIYIPFP EDDSNSTNHN LEKVEYAFLI IFTVETFLKI 180
  181 IASGLLLHPN ASVRNGWNLL DFVIVIVGLF SVILEQLTKE TEGGNHSSGK SGGFDVKALR 240
  241 AFRVLRPLRL VSGVPSLQVV LNSIIKAMVP LLHIALLVLF VIIIYAIIGL ELFIGKMHKT 300
  301 CFFADSDIVA EEDPAPCAFS GNGRQCAANG TECRSGWVGP NGGITNFDNF AFAMLTVFQC 360
  361 ITMEGWTDVL YWVNDAIGWE WPWVYFVSLI ILGSFFVLNL VLGVLSGEFS KEREKAKARG 420
  421 DFQKLREKQQ LEEDLKGYLD WITQAEDIDP ENEEEGGEEG KRNTSMPTSE TESVNTENVS 480
  481 GEGETQGCCG SLWCWWKRRG AAKTGPSGCR RWGQAISKSK LRSHGAREAL CVCRCSLESL 540
  541 VKLWTSRFSA HLQAAYVRPY SRRWRRWNRF NRRRCRAAVK SVTFYWLVIV LVFLNTLTIS 600
  601 SEHYNQPDWL TQIQDIANKV LLALFTCEML VKMYSLGLQA YFVSLFNRFD CFVVCGGITE 660
  661 TILVELELMS PLGVSVFRCV RLLRIFKVTR HWTSLSNLVA SLLNSMKSIA SLLLLLFLFI 720
  721 IIFSLLGMQL FGGKFNFDET QTKRSTFDNF PQALLTVFQI LTGEDWNAVM YDGIMAYGGP 780
  781 SSSGMIVCIY FIILFICGNY ILLKLFLAIA VDNLADAESL NTAQKEEAEE KERKKIARKE 840
  841 SLENKKNNKP EVNQIANSDN KVTIDDYQEE AEDKDPYPPC DVPVGEEEEE EEEDEPEVPA 900
  901 GPRPRRISEL NMKEKIAPIP EGSAFFILSK TNPIRVGCHK LINHHIFTNL ILVFIMLSSA 960
  961 ALAAEDPIRS HSFRNTILGY FDYAFTAIFT VEILLKMTTF GAFLHKGAFC RNYFNLLDML1020
 1021 VVGVSLVSFG IQSSAISVVK ILRVLRVLRP LRAINRAKGL KHVVQCVFVA IRTIGNIMIV1080
 1081 TTLLQFMFAC IGVQLFKGKF YRCTDEAKSN PEECRGLFIL YKDGDVDSPV VRERIWQNSD1140
 1141 FNFDNVLSAM MALFTVSTFE GWPALLYKAI DSNGENVGPV YNYRVEISIF FIIYIIIVAF1200
 1201 FMMNIFVGFV IVTFQEQGEK EYKNCELDKN QRQCVEYALK ARPLRRYIPK NPYQYKFWYV1260
 1261 VNSSPFEYMM FVLIMLNTLC LAMQHYEQSK MFNDAMDILN MVFTGVFTVE MVLKVIAFKP1320
 1321 KGYFSDAWNT FDSLIVIGSI IDVALSEADN SEESNRISIT FFRLFRVMRL VKLLSRGEGI1380
 1381 RTLLWTFIKS FQALPYVALL IAMLFFIYAV IGMQMFGKVA MRDNNQINRN NNFQTFPQAV1440
 1441 LLLFRCATGE AWQEIMLACL PGKLCDPDSD YNPGEEYTCG SNFAIVYFIS FYMLCAFLII1500
 1501 NLFVAVIMDN FDYLTRDWSI LGPHHLDEFK RIWSEYDPEA KGRIKHLDVV TLLRRIQPPL1560
 1561 GFGKLCPHRV ACKRLVAMNM PLNSDGTVMF NATLFALVRT ALKIKTEGNL EQANEELRAV1620
 1621 IKKIWKKTSM KLLDQVVPPA GDDEVTVGKF YATFLIQDYF RKFKKRKEQG LVGKYPAKNT1680
 1681 TIALQAGLRT LHDIGPEIRR AISCDLQDDE PEDSKPEEED VFKRNGALLG NYVNHVNSDR1740
 1741 RESLQQTNTT HRPLHVQRPS IPPASDTEKP LFPPAGNSVC HNHHNHNSIG KQVPTSTNAN1800
 1801 LNNANMSKAA HGKRPSIGDL EHVSENGHYS YKHDRELQRR SSIKRTRYYE TYIRSESGDE1860
 1861 QLPTIFREDP EIHGYFRDPR CFGEQEYFSS EECCEDDSSP TWSRQNYSYY NRYPGSSMDF1920
 1921 ERPRGYHHPQ GFLEDDDSPI GYDSRRSPRR RLLPPTPPSH RRSSFNFECL RRQNSQDDVL1980
 1981 PSPALPHRAA LPLHLMQQQI MAVAGLDSSK AQKYSPSHST RSWATPPATP PYRDWTPCYT2040
 2041 PLIQVDRSES MDQVNGSLPS LHRSSWYTDE PDISYRTFTP ASLTVPSSFR NKNSDKQRSA2100
 2101 DSLVEAVLIS EGLGRYARDP KFVSATKHEI ADACDLTIDE MESAASTLLN GSVCPRANGD2160
 2161 MGPISHRQDY ELQDFGPGYS DEEPDPGREE EDLADEMICI TTL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CAC1D_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: