Protein Overview: NMDE4_RAT

General Information:
Name(s) found:	NMDE4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|18202594\|sp\|Q62645.2\|NMDE4_RAT RecName: Full=Glutamate [NMDA] receptor subunit epsilon-4; AltName: Full=N-methyl D-aspartate receptor subtype 2D; Short=NMDAR2D; Short=NR2D; Flags: Precursor [NCBI NR] (Q62645) Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D-aspartate receptor subtype 2D) (NR2D) (NMDAR2D) [Swiss-Prot] Glutamate receptor ionotropic, NMDA 2D OS=Rattus norvegicus GN=Grin2d PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):1-94531237 Splice isoform 2 of Q62645 [hmr_yeast5_DM3-1_pombe.fasta] Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D-aspartate receptor subtype 2D) (NR2D) (NMDAR2D) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 2 of Glutamate [NMDA] receptor subunit epsilon 4 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Glutamate [NMDA] receptor subunit epsilon-4 precursor (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON 4 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Grin2d Isoform 2 of Glutamate [NMDA] receptor subunit epsilon-4 [rat-ipi-250309-contam.fasta] Isoform 2 of Glutamate [NMDA] receptor subunit epsilon-4 OS=Rattus norvegicus GN=Grin2d [011711_HMR.fasta] Glutamate [NMDA] receptor subunit epsilon-4 OS=Rattus norvegicus GN=Grin2d PE=1 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta] Isoform of Q62645, Glutamate receptor ionotropic, NMDA 2D OS=Rattus norvegicus GN=Grin2d PE=4 SV=3 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	1323 amino acids
Gene Ontology:
Cellular Component:	synaptosome [UNKNOWN][IEA] postsynaptic membrane [IEA] integral to membrane [IEA] cell junction [IEA] outer membrane-bounded periplasmic space [IEA] N-methyl-D-aspartate selective glutamate receptor complex [IDA] synapse [IEA] ionotropic glutamate receptor complex [TAS] plasma membrane [UNKNOWN][IEA]
Biological Process:	ion transport [IEA] [NOT]regulation of excitatory postsynaptic membrane potential [UNKNOWN] startle response [UNKNOWN][IEA] adult locomotory behavior [UNKNOWN][IEA] [NOT]detection of mechanical stimulus involved in sensory perception of pain [UNKNOWN] regulation of sensory perception of pain [UNKNOWN][IEA] synaptic transmission, glutamatergic [IMP]
Molecular Function:	protein binding [UNKNOWN][IEA] cation channel activity [IDA] neurotransmitter binding [IMP] voltage-gated cation channel activity [IMP] glutamate binding [IMP] receptor activity [IEA] ionotropic glutamate receptor activity [IDA] extracellular-glutamate-gated ion channel activity [IEA] transporter activity [IEA] N-methyl-D-aspartate selective glutamate receptor activity [UNKNOWN][IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGAGGPRGP RGPAKMLLLL ALACASPFPE EVPGPGAVGG GTGGARPLNV ALVFSGPAYA  60
   61 AEAARLGPAV AAAVRSPGLD VRPVALVLNG SDPRSLVLQL CDLLSGLRVH GVVFEDDSRA 120
  121 PAVAPILDFL SAQTSLPIVA VHGGAALVLT PKEKGSTFLQ LGSSTEQQLQ VIFEVLEEYD 180
  181 WTSFVAVTTR APGHRAFLSY IEVLTDGSLV GWEHRGALTL DPGAGEAVLG AQLRSVSAQI 240
  241 RLLFCAREEA EPVFRAAEEA GLTGPGYVWF MVGPQLAGGG GSGVPGEPLL LPGGSPLPAG 300
  301 LFAVRSAGWR DDLARRVAAG VAVVARGAQA LLRDYGFLPE LGHDCRTQNR THRGESLHRY 360
  361 FMNITWDNRD YSFNEDGFLV NPSLVVISLT RDRTWEVVGS WEQQTLRLKY PLWSRYGRFL 420
  421 QPVDDTQHLT VATLEERPFV IVEPADPISG TCIRDSVPCR SQLNRTHSPP PDAPRPEKRC 480
  481 CKGFCIDILK RLAHTIGFSY DLYLVTNGKH GKKIDGVWNG MIGEVFYQRA DMAIGSLTIN 540
  541 EERSEIVDFS VPFVETGISV MVARSNGTVS PSAFLEPYSP AVWVMMFVMC LTVVAVTVFI 600
  601 FEYLSPVGYN RSLATGKRPG GSTFTIGKSI WLLWALVFNN SVPVENPRGT TSKIMVLVWA 660
  661 FFAVIFLASY TANLAAFMIQ EEYVDTVSGL SDRKFQRPQE QYPPLKFGTV PNGSTEKNIR 720
  721 SNYPDMHSYM VRYNQPRVEE ALTQLKAGKL DAFIYDAAVL NYMARKDEGC KLVTIGSGKV 780
  781 FATTGYGIAL HKGSRWKRPI DLALLQFLGD DEIEMLERLW LSGICHNDKI EVMSSKLDID 840
  841 NMAGVFYMLL VAMGLSLLVF AWEHLVYWRL RHCLGPTHRM DFLLAFSRGM YSCCSAEAAP 900
  901 PPAKPPPPPQ PLPSPAYPAA RPPPGPAPFV PRERAAADRW RRAKGTGPPG GAAIADGFHR 960
  961 YYGPIEPQGL GLGEARAAPR GAAGRPLSPP TTQPPQKPPP SYFAIVREQE PTEPPAGAFP1020
 1021 GFPSPPAPPA AAAAAVGPPL CRLAFEDESP PAPSRWPRSD PESQPLLGGG AGGPSAGAPT1080
 1081 APPPRRAAPP PCAYLDLEPS PSDSEDSESL GGASLGGLEP WWFADFPYPY AERLGPPPGR1140
 1141 YWSVDKLGGW RAGSWDYLPP RGGPAWHCRH CASLELLPPP RHLSCSHDGL DGGWWAPPPP1200
 1201 PWAAGPPPRR RARCGCPRPH PHRPRASHRA PAAAPHHHRH RRAAGGWDFP PPAPTSRSLE1260
 1261 DLSSCPRAAP TRRLTGPSRH ARRCPHAAHW GPPLPTASHR RHRGGDLGTR RGSAHFSSLE1320
 1321 SEV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NMDE4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: