Protein Overview: PLCB1_RAT

General Information:
Name(s) found:	PLCB1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A28821 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) I - rat [NCBI NR] gi\|130223\|sp\|P10687.1\|PLCB1_RAT RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; AltName: Full=Phosphoinositide phospholipase C; AltName: Full=Phospholipase C-beta-1; Short=PLC-beta-1; AltName: Full=PLC-I; AltName: Full=PLC- [NCBI NR] gi\|117647200\|ref\|NP_001071109.1\| phospholipase C, beta 1 [Rattus norvegicus] [NCBI NR] gi\|109468875\|ref\|XP_342525.3\| PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) [Rattus norvegicus] [NCBI NR] 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 OS=Rattus norvegicus GN=Plcb1 PE=1 SV=1 [Swiss-Prot] (P10687) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-beta-1) (Phospholipase C-beta-1) (PLC-I) (PLC-154) [Swiss-Prot] Ensembl_locations(Chr-bp):3-116450881 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 [hmr_yeast5_DM3-1_pombe.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (PLC-beta-1) (Phospholipase C-beta-1) (PLC-I) (PLC-154)gi\|91896\|pir\|\|A28821 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase (EC 3.1.4.11) I - r [nrdb_11152004_Chlamydomonas] Tax_Id=10116 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phospholipase C, beta 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Plcb1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 [rat-ipi-250309-contam.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 OS=Rattus norvegicus GN=Plcb1 [011711_HMR.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 OS=Rattus norvegicus GN=Plcb1 PE=1 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1216 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] cytoplasm [UNKNOWN][IEA] membrane [IEA] cytosol [UNKNOWN][IDA]
Biological Process:	oxygen and reactive oxygen species metabolic process [IEP] signal transduction [IEA] lipid catabolic process [IEA] phosphoinositide metabolic process [IEP] learning [IEP] memory [IEP]
Molecular Function:	phosphoinositide phospholipase C activity [IDA] protein binding [IPI] protein homodimerization activity [IDA] calcium ion binding [IEA] signal transducer activity [IEA] hydrolase activity [IEA] enzyme binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGAQPGVHA LQLKPVCVSD SLKKGTKFVK WDDDSTIVTP IILRTDPQGF FFYWTDQNKE  60
   61 TELLDLSLVK DARCGKHAKA PKDPKLRELL DVGNIGHLEQ RMITVVYGPD LVNISHLNLV 120
  121 AFQEEVAKEW TNEVFSLATN LLAQNMSRDA FLEKAYTKLK LQVTPEGRIP LKNIYRLFSA 180
  181 DRKRVETALE ACSLPSSRND SIPQEDFTPD VYRVFLNNLC PRPEIDNIFS EFGAKSKPYL 240
  241 TVDQMMDFIN LKQRDPRLNE ILYPPLKQEQ VQVLIEKYEP NSSLAKKGQM SVDGFMRYLS 300
  301 GEENGVVSPE KLDLNEDMSQ PLSHYFINSS HNTYLTAGQL AGNSSVEMYR QVLLSGCRCV 360
  361 ELDCWKGRTA EEEPVITHGF TMTTEISFKE VIEAIAECAF KTSPFPILLS FENHVDSPKQ 420
  421 QAKMAEYCRL IFGDALLMEP LEKYPLESGV PLPSPMDLMY KILVKNKKKS HKSSEGSGKK 480
  481 KLSEQASNTY SDSSSVFEPS SPGAGEADTE SDDDDDDDDC KKSSMDEGTA GSEAMATEEM 540
  541 SNLVNYIQPV KFESFETSKK RNKSFEMSSF VETKGLEQLT KSPVEFVEYN KMQLSRIYPK 600
  601 GTRVDSSNYM PQLFWNAGCQ MVALNFQTVD LAMQINMGMY EYNGKSGYRL KPEFMRRPDK 660
  661 HFDPFTEGIV DGIVANTLSV KIISGQFLSD KKVGTYVEVD MFGLPVDTRR KAFKTKTSQG 720
  721 NAVNPVWEEE PIVFKKVVLP SLACLRIAAY EEGGKFIGHR ILPVQAIRPG YHYICLRNER 780
  781 NQPLMLPAVF VYIEVKDYVP DTYADVIEAL SNPIRYVNLM EQRAKQLAAL TLEDEEEVKK 840
  841 EADPGETSSE APSETRTTPA ENGVNHTATL APKPPSQAPH SQPAPGSVKA PAKTEDLIQS 900
  901 VLTEVEAQTI EELKQQKSFV KLQKKHYKEM KDLVKRHHKK TTELIKEHTT KYNEIQNDYL 960
  961 RRRAALEKSA KKDSKKKSEP SSPDHGSSAI EQDLAALDAE MTQKLIDLKD KQQQQLLNLR1020
 1021 QEQYYSEKYQ KREHIKLLIQ KLTDVAEECQ NNQLKKLKEI CEKEKKELKK KMDKKRQEKI1080
 1081 TEAKSKDKSQ MEEEKTEMIR SYIQEVVQYI KRLEEAQSKR QEKLVEKHKE IRQQILDEKP1140
 1141 KLQMELEQEY QDKFKRLPLE ILEFVQEAMK GKVSEDSNHG SAPPSLASDP AKVNLKSPSS1200
 1201 EEVQGENAGR EFDTPL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PLCB1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: