Protein Overview: TNFB_RAT

General Information:
Name(s) found:	TNFB_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|549087\|sp\|Q06332.1\|TNFB_RAT RecName: Full=Lymphotoxin-alpha; Short=LT-alpha; AltName: Full=TNF-beta; AltName: Full=Tumor necrosis factor ligand superfamily member 1; Flags: Precursor [NCBI NR] gi\|478314\|pir\|\|JN0869 tumor necrosis factor beta - rat [NCBI NR] gi\|46237627\|emb\|CAE84004.1\| lymphotoxin alpha (TNF superfamily, member 1) [Rattus norvegicus] [NCBI NR] gi\|205255\|gb\|AAA16276.1\| lymphotoxin [NCBI NR] gi\|18158437\|ref\|NP_542947.1\| lymphotoxin alpha (TNF superfamily, member 1) [Rattus norvegicus] [NCBI NR] Lymphotoxin-alpha OS=Rattus norvegicus GN=Lta PE=3 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):20-4520299 Lymphotoxin-alpha precursor [hmr_yeast5_DM3-1_pombe.fasta] lymphotoxin A; Lymphotoxin alpha (formerly tumor necrosis factor, beta); Lymphotoxin alpha (formerly tumor necrosis factor beta) [HMR_022704-rand.fasta] lymphotoxin alpha (TNF superfamily, member 1) [Rattus norvegicus]gi\|18158437\|ref\|NP_542947.1\| lymphotoxin A [Rattus norvegicus]gi\|549087\|sp\|Q06332\|TNFB_RAT Lymphotoxin-alpha precursor (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily membe [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Lymphotoxin-alpha precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_080769) lymphotoxin alpha (formerly tumor necrosis factor, beta) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Lymphotoxin-alpha precursor (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] lymphotoxin A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] lymphotoxin alpha (TNF superfamily, member 1) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] lymphotoxin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 LYMPHOTOXIN-ALPHA PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Lta Lymphotoxin-alpha [rat-ipi-250309-contam.fasta] lymphotoxin-alpha precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Lymphotoxin-alpha OS=Rattus norvegicus GN=Lta [011711_HMR.fasta] Lymphotoxin-alpha OS=Rattus norvegicus GN=Lta PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	202 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IEA] membrane [IEA] extracellular region [IEA]
Biological Process:	positive regulation of chronic inflammatory response to antigenic stimulus [UNKNOWN] negative regulation of growth of symbiont in host [UNKNOWN] negative regulation of fibroblast proliferation [IDA] humoral immune response [UNKNOWN][IEA] positive regulation of interferon-gamma production [UNKNOWN] positive regulation of apoptosis [IMP] positive regulation of humoral immune response mediated by circulating immunoglobulin [UNKNOWN] response to nutrient [IEP] response to lipopolysaccharide [IEP] lymph node development [UNKNOWN][IEA] defense response to Gram-positive bacterium [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN] tumor necrosis factor receptor binding [IEA] cytokine activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPLGRLHLL RVLSTPPVFL LGLLLALPLG AQGLSGVRFS ASRTAHQPPQ KHLTHGLLKP  60
   61 AAHLVGYPSK QNSLLWRANT DRAFLRHGFS LNNNSLLIPT SGLYFVYSQV VFSGESCSPR 120
  121 AIPTPIYLAH EVQLFSSQYP FHVPLLSAQK SVYPGLQGPW VRSMYQGAVF LLSKGDQLST 180
  181 HTDGISHLHF SPSTVFFGAF AL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TNFB_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: