Protein Overview: TTP_RAT

General Information:
Name(s) found:	TTP_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9971206\|dbj\|BAB12432.1\| TIS11 [Rattus norvegicus] [NCBI NR] gi\|37805235\|gb\|AAH60308.1\| Zinc finger protein 36 [Rattus norvegicus] [NCBI NR] gi\|18959224\|ref\|NP_579824.1\| zinc finger protein 36 [Rattus norvegicus] [NCBI NR] gi\|1717819\|sp\|P47973.1\|TTP_RAT RecName: Full=Tristetraproline; Short=TTP; AltName: Full=Zinc finger protein 36; Short=Zfp-36; AltName: Full=Protein TIS11A; Short=TIS11 [NCBI NR] pir\|\|JC1255 TIS11 protein - rat [NCBI NR] Tristetraprolin OS=Rattus norvegicus GN=Zfp36 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-80884758 Tristetraproline [hmr_yeast5_DM3-1_pombe.fasta] zinc finger protein 36 [HMR_022704-rand.fasta] zinc finger protein 36 [Rattus norvegicus]gi\|37805235\|gb\|AAH60308.1\| Zinc finger protein 36 [Rattus norvegicus]gi\|57759\|emb\|CAA44970.1\| Tis 11 protein [Rattus rattus]gi\|9971206\|dbj\|BAB12432.1\| TIS11 [Rattus norvegicus]gi\|112401\|pir\|\|JC1255 TIS11 prote [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tristetraproline [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_133290) zinc finger protein 36 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (Protein TIS11A) (TIS11) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Zinc finger protein 36 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] TIS11 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRISTETRAPROLINE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] zinc finger protein 36 [Rattus norvegicus] [nr-271106-contam.fasta] Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) [nr-271106-contam.fasta] Tristetraprolin OS=Rattus norvegicus GN=Zfp36 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	320 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][ISS] cytoplasm [UNKNOWN][IDA][ISS] cytosol [UNKNOWN][IEA]
Biological Process:	negative regulation of myeloid cell differentiation [UNKNOWN][IEA] positive regulation of transcription, DNA-dependent [TAS] negative regulation of inflammatory response [UNKNOWN][IEA] intracellular protein kinase cascade [UNKNOWN][IEA] regulation of mRNA stability [UNKNOWN][IEA] RNA destabilization [UNKNOWN][IEA] mRNA catabolic process [UNKNOWN][ISS] positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [UNKNOWN][ISS] nuclear-transcribed mRNA poly(A) tail shortening [UNKNOWN] nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [UNKNOWN]
Molecular Function:	AU-rich element binding [UNKNOWN][ISS] DNA binding [IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] metal ion binding [IEA] mRNA binding [UNKNOWN][IEA] transcription activator activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLSAIYESL MSMSHDLSPD HGGTESSGGL WNINSSDSIP SGVTSRLTGR STSLVEGRSC  60
   61 SWVPPPPGFA PLAPRPGPEL SPSPTSPTAT PTTSSRYKTE LCRTYSESGR CRYGAKCQFA 120
  121 HGPGELRQAN RHPKYKTELC HKFYLQGRCP YGSRCHFIHN PTEDLALPGQ PHVLRQSISF 180
  181 SGLPSGRRTS PPPPGFSGPS LSSCSFSPSS SPPPPGDLPL SPSAFSAAPG TPVSRRDPTP 240
  241 ACCPSCRRST TPSTIWGPLG GLARSPSAHS LGSDPDDYAS SGSSLGGSDS PVFEAGVFGP 300
  301 PQPPAPPRRL PIFNRISVSE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TTP_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: