Protein Overview: LCAT_RAT

General Information:
Name(s) found:	LCAT_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393703\|ref\|NP_058720.1\| lecithin cholesterol acyltransferase [Rattus norvegicus] [NCBI NR] gi\|56564\|emb\|CAA38030.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|125995\|sp\|P18424.1\|LCAT_RAT RecName: Full=Phosphatidylcholine-sterol acyltransferase; AltName: Full=Lecithin-cholesterol acyltransferase; AltName: Full=Phospholipid-cholesterol acyltransferase; Flags: Precursor [NCBI NR] Phosphatidylcholine-sterol acyltransferase OS=Rattus norvegicus GN=Lcat PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):19-33757350 Phosphatidylcholine-sterol acyltransferase precursor [hmr_yeast5_DM3-1_pombe.fasta] lecithin cholesterol acyltransferase; Lecithin-cholesterol acyltransferase [HMR_022704-rand.fasta] lecithin cholesterol acyltransferase [Rattus norvegicus]gi\|56564\|emb\|CAA38030.1\| unnamed protein product [Rattus norvegicus]gi\|125995\|sp\|P18424\|LCAT_RAT Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospho [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Phosphatidylcholine-sterol acyltransferase precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017024) lecithin-cholesterol acyltransferase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] lecithin cholesterol acyltransferase [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Lcat Phosphatidylcholine-sterol acyltransferase [rat-ipi-250309-contam.fasta] Phosphatidylcholine-sterol acyltransferase OS=Rattus norvegicus GN=Lcat [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	440 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IEA] high-density lipoprotein particle [UNKNOWN][IEA] extracellular region [UNKNOWN]
Biological Process:	very-low-density lipoprotein particle remodeling [UNKNOWN][IEA] high-density lipoprotein particle remodeling [UNKNOWN][IEA] cholesterol metabolic process [UNKNOWN][IDA] response to copper ion [IDA] steroid metabolic process [IEA] lipoprotein metabolic process [IDA] phospholipid metabolic process [UNKNOWN][IEA] lipoprotein biosynthetic process [UNKNOWN][IEA] phosphatidylcholine biosynthetic process [UNKNOWN][IEA] cholesterol homeostasis [UNKNOWN][IEA] reverse cholesterol transport [UNKNOWN][IEA] lipid metabolic process [IEA] response to glucocorticoid stimulus [IDA] cholesterol esterification [UNKNOWN][IEA] cholesterol transport [UNKNOWN]
Molecular Function:	phospholipase A2 activity [IDA] protein binding [UNKNOWN][IEA] phosphatidylcholine-sterol O-acyltransferase activity [UNKNOWN][IDA] apolipoprotein A-I binding [UNKNOWN][IEA] transferase activity [IEA] acyltransferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLPGSPWQW VLLLLGLLLP PATSFWLLNV LFPPHTTPKA ELSNHTRPVI LVPGCMGNRL  60
   61 EAKLDKPNVV NWLCYRKTED FFTIWLDFNM FLPLGVDCWI DNTRVVYNRS SGHMSNAPGV 120
  121 QIRVPGFGKT YSVEYLDDNK LAGYLNTLVQ NLVNNGYVRD ETVRAAPYDW RLAPRQQDEY 180
  181 YQKLAGLVEE MYAAYGKPVF LIGHSLGCLH VLHFLLRQPQ SWKDHFIDGF ISLGAPWGGS 240
  241 IKPMRILASG DNQGIPIMSN IKLREEQRIT TTSPWMFPAH HVWPEDHVFI STPNFNYTGQ 300
  301 DFERFFADLH FEEGWHMFLQ SRDLLAGLPA PGVEVYCLYG VGMPTAHTYI YDHNFPYKDP 360
  361 VAALYEDGDD TVATRSTELC GQVQGRQSQG VHLLRMNGTD HLNMVFSNKT LEHINAILLG 420
  421 AYPHGTPKSP TASLGPPPTE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LCAT_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: