Protein Overview: DCE2_RAT

General Information:
Name(s) found:	DCE2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JH0423 glutamate decarboxylase (EC 4.1.1.15) 2 [validated] - rat [NCBI NR] gi\|6978871\|ref\|NP_036695.1\| glutamate decarboxylase 2 [Rattus norvegicus] [NCBI NR] gi\|204226\|gb\|AAA63488.1\| glutamic acid decarboxylase [NCBI NR] gi\|149028599\|gb\|EDL83940.1\| glutamic acid decarboxylase 2, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|1352219\|sp\|Q05683.1\|DCE2_RAT RecName: Full=Glutamate decarboxylase 2; AltName: Full=Glutamate decarboxylase 65 kDa isoform; AltName: Full=65 kDa glutamic acid decarboxylase; AltName: Full=GAD-65 [NCBI NR] Glutamate decarboxylase 2 OS=Rattus norvegicus GN=Gad2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):17-93506540 Glutamate decarboxylase, 65 kDa isoform [hmr_yeast5_DM3-1_pombe.fasta] glutamate decarboxylase 2; Glutamate decarboxylase 2 (islet) [HMR_022704-rand.fasta] glutamate decarboxylase 2 [Rattus norvegicus]gi\|1352219\|sp\|Q05683\|DCE2_RAT Glutamate decarboxylase, 65 kDa isoform (GAD-65) (65 kDa glutamic acid decarboxylase)gi\|92290\|pir\|\|JH0423 glutamate decarboxylase (EC 4.1.1.15) 2 [validated] - ratgi\|204226\|gb\|A [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Glutamate decarboxylase 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012563) glutamate decarboxylase 2 (islet) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Glutamate decarboxylase 2 (Glutamate decarboxylase 65 kDa isoform) (65 kDa glutamic acid decarboxylase) (GAD-65) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamic acid decarboxylase 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamic acid decarboxylase 2, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamic acid decarboxylase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GLUTAMATE DECARBOXYLASE, 65 KDA ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] glutamate decarboxylase 2 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Glutamate decarboxylase 2 (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Gad2 Glutamate decarboxylase 2 [rat-ipi-250309-contam.fasta] Glutamate decarboxylase 2 OS=Rattus norvegicus GN=Gad2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	585 amino acids
Gene Ontology:
Cellular Component:	perinuclear region of cytoplasm [IDA] cytoplasmic vesicle [IDA] synaptic vesicle membrane [IDA] synapse [UNKNOWN] axon [UNKNOWN] anchored to membrane [IDA]
Biological Process:	response to drug [IEP] synaptic transmission [TAS] glutamate decarboxylation to succinate [IDA]
Molecular Function:	protein binding [UNKNOWN] glutamate decarboxylase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPGSGFWS FGSEDGSGDP ENPGTARAWC QVAQKFTGGI GNKLCALLYG DSEKPAESGG  60
   61 SVTSRAATRK VACTCDQKPC SCPKGDVNYA LLHATDLLPA CEGERPTLAF LQDVMNILLQ 120
  121 YVVKSFDRST KVIDFHYPNE LLQEYNWELA DQPQNLEEIL THCQTTLKYA IKTGHPRYFN 180
  181 QLSTGLDMVG LAADWLTSTA NTNMFTYEIA PVFVLLEYVT LKKMREIIGW PGGSGDGIFS 240
  241 PGGAISNMYA MLIARYKMFP EVKEKGMAAV PRLIAFTSEH SHFSLKKGAA ALGIGTDSVI 300
  301 LIKCDERGKM IPSDLERRIL EVKQKGFVPF LVSATAGTTV YGAFDPLLAV ADICKKYKIW 360
  361 MHVDAAWGGG LLMSRKHKWK LNGVERANSV TWNPHKMMGV PLQCSALLVR EEGLMQSCNQ 420
  421 MHASYLFQQD KHYDLSYDTG DKALQCGRHV DVFKLWLMWR AKGTTGFEAH IDKCLELAEY 480
  481 LYNIIKNREG YEMVFDGKPQ HTNVCFWFVP PSLRVLEDNE ERMSRLSKVA PVIKARMMEY 540
  541 GTTMVSYQPL GDKVNFFRMV ISNPAATHQD IDFLIEEIER LGQDL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.87

Protein Overview: DCE2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: