Protein Overview: HBEGF_RAT

General Information:
Name(s) found:	HBEGF_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|729691\|sp\|Q06175.1\|HBEGF_RAT RecName: Full=Proheparin-binding EGF-like growth factor; Contains: RecName: Full=Heparin-binding EGF-like growth factor; Short=HB-EGF; Short=HBEGF; Flags: Precursor [NCBI NR] gi\|6978785\|ref\|NP_037077.1\| heparin-binding EGF-like growth factor [Rattus norvegicus] [NCBI NR] pir\|\|JC1409 heparin-binding EGF-like growth factor precursor - rat [NCBI NR] gi\|204290\|gb\|AAA81780.1\| heparin-binding EGF-like growth factor [Rattus norvegicus] [NCBI NR] (Q06175) Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) [Swiss-Prot] Proheparin-binding EGF-like growth factor OS=Rattus norvegicus GN=Hbegf PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):18-60362330 Heparin-binding EGF-like growth factor precursor [hmr_yeast5_DM3-1_pombe.fasta] diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); heparin-binding epidermal -growth - like growth factor; heparin binding epidermal growth factor-like growth factor; heparin-binding epide [HMR_022704-rand.fasta] diphtheria toxin receptor [Rattus norvegicus]gi\|204290\|gb\|AAA81780.1\| heparin-binding EGF-like growth factor [Rattus norvegicus]gi\|347015\|pir\|\|JC1409 heparin-binding EGF-like growth factor precursor - ratgi\|729691\|sp\|Q06175\|HBGF_RAT Heparin-binding EGF [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Heparin-binding EGF-like growth factor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012945) diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Proheparin-binding EGF-like growth factor precursor [Contains: Heparin-binding EGF-like growth factor (HB-EGF) (HBEGF)] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] heparin-binding EGF-like growth factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HEPARIN-BINDING EGF-LIKE GROWTH FACTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) [nr-271106-contam.fasta] diphtheria toxin receptor [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Hbegf Proheparin-binding EGF-like growth factor [rat-ipi-250309-contam.fasta] Proheparin-binding EGF-like growth factor OS=Rattus norvegicus GN=Hbegf [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	208 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA] extracellular space [UNKNOWN][IEA] extracellular region [IEA] plasma membrane [IEA] cell surface [UNKNOWN][IEA]
Biological Process:	positive regulation of smooth muscle cell proliferation [IEA] positive regulation of cell growth [IDA] epidermal growth factor receptor signaling pathway [UNKNOWN][IMP][TAS] nervous system development [TAS] regulation of heart contraction [UNKNOWN][IEA] positive regulation of keratinocyte migration [IEA] wound healing, spreading of epidermal cells [IEA] negative regulation of elastin biosynthetic process [IDA]
Molecular Function:	growth factor activity [IEA][IMP] epidermal growth factor receptor binding [IEA][IMP] heparin binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLPSVVLK LFLAAVLSAL VTGESLERLR RGLAAATSNP DPPTGTTNQL LPTGADRAQE  60
   61 VQDLEGTDLD LFKVAFSSKP QALATPGKEK NGKKKRKGKG LGKKRDPCLK KYKDYCIHGE 120
  121 CRYLKELRIP SCHCLPGYHG QRCHGLTLPV ENPLYTYDHT TVLAVVAVVL SSVCLLVIVG 180
  181 LLMFRYHRRG GYDLESEEKV KLGMASSH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HBEGF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: