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Protein Overview: NTF3_RAT

General Information:
Name(s) found: NTF3_RAT [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Neurotrophin-3 OS=Rattus norvegicus GN=Ntf3 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 258 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic membrane-bounded vesicle [UNKNOWN][IEA]
    extracellular region [UNKNOWN]
    plasma membrane [IMP]
    Biological Process: neuromuscular synaptic transmission [UNKNOWN][IEA]
    nervous system development [IMP]
    epidermis development [UNKNOWN][IEA]
    positive regulation of glial cell differentiation [IDA]
    axon guidance [UNKNOWN][IEA]
    peripheral nervous system development [UNKNOWN][IEA]
    myelination [IDA]
    brain development [UNKNOWN][IEA]
    neuron development [UNKNOWN][IEA]
    generation of neurons [UNKNOWN][IEA]
    glial cell fate determination [UNKNOWN][IEA]
    regulation of neuron apoptosis [UNKNOWN][IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    nerve development [UNKNOWN][IEA]
    enteric nervous system development [UNKNOWN][IEA]
    smooth muscle cell differentiation [UNKNOWN][IEA]
    mechanoreceptor differentiation [UNKNOWN][IEA]
    regulation of synaptic transmission [IDA]
    Molecular Function: growth factor activity [IEA]
    protein binding [UNKNOWN]
    neurotrophin receptor binding [IEA]
    nerve growth factor binding [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSILFYVIFL AYLRGIQGNN MDQRSLPEDS LNSLIIKLIQ ADILKNKLSK QMVDVKENYQ  60
   61 STLPKAEAPR EPEQGEATRS EFQPMIATDT ELLRQQRRYN SPRVLLSDST PLEPPPLYLM 120
  121 EDYVGNPVVT NRTSPRRKRY AEHKSHRGEY SVCDSESLWV TDKSSAIDIR GHQVTVLGEI 180
  181 KTGNSPVKQY FYETRCKEAR PVKNGCRGID DKHWNSQCKT SQTYVRALTS ENNKLVGWRW 240
  241 IRIDTSCVCA LSRKIGRT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.64

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle