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Protein Overview: MYH7_RAT

General Information:
Name(s) found: MYH7_RAT [Swiss-Prot]
Description(s) found:
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  • pir||S06006 myosin beta heavy chain, cardiac muscle [similarity] - rat [NCBI NR]
  • gi|8393807|ref|NP_058936.1| myosin, heavy chain 7, cardiac muscle, beta [Rattus norvegicus] [NCBI NR]
  • gi|56657|emb|CAA34065.1| unnamed protein product [Rattus norvegicus] [NCBI NR]
  • gi|127748|sp|P02564.2|MYH7_RAT RecName: Full=Myosin-7; AltName: Full=Myosin heavy chain 7; AltName: Full=Myosin heavy chain, cardiac muscle beta isoform; Short=MyHC-beta; AltName: Full=Myosin heavy chain slow isoform; Short=MyHC-slow [NCBI NR]
  • Myosin-7 OS=Rattus norvegicus GN=Myh7 PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):15-31966878 Myosin heavy chain, cardiac muscle beta isoform [hmr_yeast5_DM3-1_pombe.fasta]
  • myosin heavy chain, polypeptide 7; myosin heavy chain, cardiac muscle, fetal; myosin, heavy polypeptide 7, cardiac muscle, beta; myosin heavy chain polypeptide 7 cardiac muscle fetal; myosin heavy chain cardiac muscle fetal; myosin heavy polypeptide 7 car [HMR_022704-rand.fasta]
  • myosin heavy chain, polypeptide 7 [Rattus norvegicus]gi|56657|emb|CAA34065.1| unnamed protein product [Rattus norvegicus]gi|127748|sp|P02564|MYH7_RAT Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)gi|92499|pir||S06006 myosin beta heavy chai [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Myosin heavy chain, cardiac muscle beta isoform [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_017240) myosin heavy chain, polypeptide 7; myosin heavy chain, cardiac muscle, fetal; myosin, heavy polypeptide 7, cardiac muscle, beta [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta) (Myosin heavy chain slow isoform) (MyHC-slow) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • myosin, heavy polypeptide 7, cardiac muscle, beta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 MYOSIN HEAVY CHAIN, CARDIAC MUSCLE BETA ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • myosin, heavy chain 7, cardiac muscle, beta [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta) [nr-271106-contam.fasta]
  • myosin heavy chain, polypeptide 7 [Rattus norvegicus] [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Myh7 Myosin-7 [rat-ipi-250309-contam.fasta]
  • Myosin-7 OS=Rattus norvegicus GN=Myh7 [011711_HMR.fasta]
  • Myosin-7 OS=Rattus norvegicus GN=Myh7 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 1935 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    myosin complex [UNKNOWN][IEA]
    contractile fiber [IMP]
    muscle myosin complex [IDA]
    focal adhesion [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][IEA]
    myosin filament [IEA]
    nucleolus [UNKNOWN][IEA]
    myofibril [UNKNOWN][IEA]
    Biological Process: regulation of heart rate [UNKNOWN][IEA]
    ventricular cardiac muscle tissue morphogenesis [UNKNOWN][IEA]
    muscle contraction [UNKNOWN][IMP]
    ATP catabolic process [UNKNOWN][IMP]
    response to reactive oxygen species [IEP]
    adult heart development [UNKNOWN][IEA]
    muscle filament sliding [UNKNOWN][IEA]
    Molecular Function: ATPase activity [UNKNOWN][IMP]
    protein homodimerization activity [IDA]
    microfilament motor activity [IMP]
    motor activity [IEA]
    nucleotide binding [IEA]
    actin filament binding [IEA]
    ATP binding [IEA][IMP]
    actin-dependent ATPase activity [UNKNOWN][IEA]
    calmodulin binding [IEA]
    protein binding [UNKNOWN][IEA]
    structural constituent of muscle [UNKNOWN][IEA]
    actin binding [IEA]
    protein heterodimerization activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADREMAAFG AGAPFLRKSE KERLEAQTRP FDLKKDVFVP DDKEEFVKAK IVSREGGKVT  60
   61 AETENGKTVT VKEDQVMQQN PPKFDKIEDM AMLTFLHEPA VLYNLKERYA SWMIYTYSGL 120
  121 FCVTVNPYKW LPVYNAQVVA AYRGKKRSEA PPHIFSISDN AYQYMLTDRE NQSILITGES 180
  181 GAGKTVNTKR VIQYFAVIAA IGDRSKKDQT PGKGTLEDQI IQANPALEAF GNAKTVRNDN 240
  241 SSRFGKFIRI HFGATGKLAS ADIETYLLEK SRVIFQLKAE RDYHIFYQIL SNKKPELLDM 300
  301 LLITNNPYDY AFFSQGETTV ASIDDSEEHM ATDSAFDVLG FTPEEKNSIY KLTGAIMHFG 360
  361 NMKFKQKQRE EQAEPDGTEE ADKSAYLMGL NSADLLKGLC HPRVKVGNEY VTKGQNVQQV 420
  421 AYAIGALAKS VYEKMFNWMV TRINATLETK QPRQYFIGVL DIAGFEIFDF NSFEQLCINF 480
  481 TNEKLQQFFN HHMFVLEQEE YKKEGIEWTF IDFGMDLQAC IDLIEKPMGI MSILEEECMF 540
  541 PKATDMTFKA KLYDNHLGKS NNFQKPRNIK GKQEAHFSLI HYAGTVDYNI LGWLQKNKDP 600
  601 LNETVVGLYQ KSSLKLLSNL FANYAGADAP VDKGKGKAKK GSSFQTVSAL HRENLNKLMT 660
  661 NLRSTHPHFV RCIIPNETKS PGVMDNPLVM HQLRCNGVLE GIRICRKGFP NRILYGDFRQ 720
  721 RYRILNPAAI PEGQFIDSRK GAEKLLGSLD IDHNQYKFGH TKVFFKAGLL GLLEEMRDER 780
  781 LSRIITRIQA QSRGVLSRME FKKLLERRDS LLIIQWNIRA FMGVKNWPWM KLYFKIKPLL 840
  841 KSAETEKEMA NMKEEFGRVK DALEKSEARR KELEEKMVSL LQEKNDLQLQ VQAEQDNLAD 900
  901 AEERCDQLIK NKIQLEAKVK EMTERLEDEE EMNAELTAKK RKLEDECSEL KRDIDDLELT 960
  961 LAKVEKEKHA TENKVKNLTE EMAGLDEIIV KLTKEKKALQ EAHQQALDDL QAEEDKVNTL1020
 1021 TKAKVKLEQQ VDDLEGSLDQ DKKVRMDLER AKRKLEGDLK LTQESIMDLE NDKQQLDERL1080
 1081 KKKDFELNAL NARIEDEQAL GSQLQKKLKE LQARIEELEE ELEAERTARA KVEKLRSDLS1140
 1141 RELEEISERL EEAGGATSVQ IEMNKKREAE FQKMRRDLEE ATLQHEATAA ALRKKHADSV1200
 1201 AELGEQIDNL QRVKQKLEKE KSEFKLELDD VTSNMEQIIK AKANLEKMCR TLEDQMNEHR1260
 1261 SKAEETQRSV NDLTRQRAKL QTENGELSRQ LDEKEALISQ LTRGKLTYTQ QLEDLKRQLE1320
 1321 EEVKAKNALA HALQSARHDC DLLREQYEEE TEAKAELQRV LSKANSEVAQ WRTKYETDAI1380
 1381 QRTEELEEAK KKLAQRLQDA EEAVEAVNAK CSSLEKTKHR LQNEIEDLMV DVERSNAAAA1440
 1441 ALDKKQRNFD KILVEWKQKY EESQSELESS QKEARSLSTE LFKLKNAYEE SLEHLETFKR1500
 1501 ENKNLQEEIS DLTEQLGSTG KSIHELEKIR KQLEAEKLEL QSALEEAEAS LEHEEGKILR1560
 1561 AQLEFNQIKA EIERKLAEKD EEMEQAKRNH LRVVDSLQTS LDAETRSRNE ALRVKKKMEG1620
 1621 DLNEMEIQLS HANRMAAEAQ KQVKSLQSLL KDTQIQLDDA VRANDDLKEN IAIVERRNNL1680
 1681 LQAELEELRA VVEQTERSRK LAEQELIETS ERVQLLHSQN TSLINQKKKM DADLSQLQTE1740
 1741 VEEAVQECRN AEEKAKKAIT DAAMMAEELK KEQDTSAHLE RMKNNMEQTI KDLQHRLDEA1800
 1801 EQIALKGGKK QLQKLEARVR ELENELEAEQ KRNAESVKGM RKSERRIKEL TYQTEEDRKN1860
 1861 LLRLQDLVDK LQLKVKAYKR QAEEAEEQAN TNLSKFRKVQ HELDEAEERA DIAESQVNKL1920
 1921 RAKSRDIGAK GLNEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle