Protein Overview: ACHA4_RAT

General Information:
Name(s) found:	ACHA4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8469182\|sp\|P09483.3\|ACHA4_RAT RecName: Full=Neuronal acetylcholine receptor subunit alpha-4; Flags: Precursor [NCBI NR] Neuronal acetylcholine receptor subunit alpha-4 OS=Rattus norvegicus GN=Chrna4 PE=1 SV=3 [Swiss-Prot] (P09483) Neuronal acetylcholine receptor protein, alpha-4 chain precursor [Swiss-Prot] Ensembl_locations(Chr-bp):3-163240096 Splice isoform Alpha-4-1 of P09483 [hmr_yeast5_DM3-1_pombe.fasta] Neuronal acetylcholine receptor protein, alpha-4 chain precursor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Alpha-4-1 of Neuronal acetylcholine receptor protein, alpha-4 subunit precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform Alpha-4-1 of Neuronal acetylcholine receptor protein, alpha-4 chain precursor [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Neuronal acetylcholine receptor subunit alpha-4 precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-4 CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Neuronal acetylcholine receptor protein subunit alpha-4 precursor [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Chrna4 Isoform Alpha-4-1 of Neuronal acetylcholine receptor subunit alpha-4 [rat-ipi-250309-contam.fasta] Isoform Alpha-4-1 of Neuronal acetylcholine receptor subunit alpha-4 OS=Rattus norvegicus GN=Chrna4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	630 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IDA] dendrite [IDA] postsynaptic membrane [IEA] membrane [IEA] external side of plasma membrane [UNKNOWN] integral to membrane [IEA] cell junction [IEA] nicotinic acetylcholine-gated receptor-channel complex [UNKNOWN][IDA][IMP][TAS] neuronal cell body [IDA] synapse [IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	regulation of dopamine secretion [UNKNOWN] DNA repair [UNKNOWN] synaptic transmission, cholinergic [UNKNOWN][IMP] behavioral response to nicotine [UNKNOWN] signal transduction [UNKNOWN] protein heterooligomerization [IDA] response to nicotine [UNKNOWN] B cell activation [UNKNOWN] behavior [UNKNOWN] response to oxidative stress [UNKNOWN] ion transport [IEA] response to hypoxia [UNKNOWN] locomotory behavior [UNKNOWN] regulation of membrane potential [UNKNOWN] cognition [UNKNOWN] calcium ion transport [UNKNOWN] regulation of inhibitory postsynaptic membrane potential [UNKNOWN] sensory perception of pain [UNKNOWN] regulation of action potential [UNKNOWN] membrane depolarization [UNKNOWN] neurological system process [UNKNOWN]
Molecular Function:	ion channel activity [UNKNOWN][IEA] nicotinic acetylcholine-activated cation-selective channel activity [IC][UNKNOWN][IDA][IEA] protein binding [UNKNOWN][IDA] acetylcholine receptor activity [UNKNOWN] drug binding [IDA] extracellular ligand-gated ion channel activity [IEA] acetylcholine binding [IDA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANSGTGAPP PLLLLPLLLL LGTGLLPASS HIETRAHAEE RLLKRLFSGY NKWSRPVANI  60
   61 SDVVLVRFGL SIAQLIDVDE KNQMMTTNVW VKQEWHDYKL RWDPGDYENV TSIRIPSELI 120
  121 WRPDIVLYNN ADGDFAVTHL TKAHLFYDGR VQWTPPAIYK SSCSIDVTFF PFDQQNCTMK 180
  181 FGSWTYDKAK IDLVSMHSRV DQLDFWESGE WVIVDAVGTY NTRKYECCAE IYPDITYAFI 240
  241 IRRLPLFYTI NLIIPCLLIS CLTVLVFYLP SECGEKVTLC ISVLLSLTVF LLLITEIIPS 300
  301 PTSLVIPLIG EYLLFTMIFV TLSIVITVFV LNVHHRSPRT HTMPAWVRRV FLDIVPRLLF 360
  361 MKRPSVVKDN CRRLIESMHK MANAPRFWPE PVGEPGILSD ICNQGLSPAP TFCNPTDTAV 420
  421 ETQPTCRSPP LEVPDLKTSE VEKASPCPSP GSCPPPKSSS GAPMLIKARS LSVQHVPSSQ 480
  481 EAAEDGIRCR SRSIQYCVSQ DGAASLADSK PTSSPTSLKA RPSQLPVSDQ ASPCKCTCKE 540
  541 PSPVSPVTVL KAGGTKAPPQ HLPLSPALTR AVEGVQYIAD HLKAEDTDFS VKEDWKYVAM 600
  601 VIDRIFLWMF IIVCLLGTVG LFLPPWLAAC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACHA4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: