Protein Overview: CSK_RAT

General Information:
Name(s) found:	CSK_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S15094 protein-tyrosine kinase (EC 2.7.1.112) CSK - rat [NCBI NR] gi\|71795633\|ref\|NP_001025210.1\| c-src tyrosine kinase [Rattus norvegicus] [NCBI NR] gi\|71051761\|gb\|AAH98863.1\| C-src tyrosine kinase [Rattus norvegicus] [NCBI NR] gi\|417209\|sp\|P32577.1\|CSK_RAT RecName: Full=Tyrosine-protein kinase CSK; AltName: Full=C-SRC kinase [NCBI NR] ref\|XP_236290.2\| similar to Tyrosine-protein kinase CSK (C-SRC kinase) [Rattus norvegicus] [NCBI NR] gi\|227724\|prf\|\|1709363A protein Tyr kinase CSK [NCBI NR] gi\|20150734\|pdb\|1K9A\|F Chain F, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI NR] gi\|20150733\|pdb\|1K9A\|E Chain E, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI NR] gi\|20150732\|pdb\|1K9A\|D Chain D, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI NR] gi\|20150731\|pdb\|1K9A\|C Chain C, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI NR] gi\|20150730\|pdb\|1K9A\|B Chain B, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI NR] gi\|20150729\|pdb\|1K9A\|A Chain A, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI NR] gi\|149041803\|gb\|EDL95644.1\| c-src tyrosine kinase [Rattus norvegicus] [NCBI NR] Tyrosine-protein kinase CSK OS=Rattus norvegicus GN=Csk PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-59794085 Tyrosine-protein kinase CSK [hmr_yeast5_DM3-1_pombe.fasta] similar to Tyrosine-protein kinase CSK (C-SRC kinase) [HMR_022704-rand.fasta] similar to Tyrosine-protein kinase CSK (C-SRC kinase) [Rattus norvegicus]gi\|57508\|emb\|CAA41484.1\| protein-tyrosine kinase (CSK) [Rattus sp.]gi\|20150734\|pdb\|1K9A\|F Chain F, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A R [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tyrosine-protein kinase CSK [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Chain F, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Chain E, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Chain D, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Chain C, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Chain B, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Chain A, Crystal Structure Analysis Of Full-Length Carboxyl-Terminal Src Kinase At 2.5 A Resolution [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tyrosine-protein kinase CSK (C-SRC kinase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] c-src tyrosine kinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] C-src tyrosine kinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] protein Tyr kinase CSK [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TYROSINE-PROTEIN KINASE CSK [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Csk Tyrosine-protein kinase CSK [rat-ipi-250309-contam.fasta] Tyrosine-protein kinase CSK OS=Rattus norvegicus GN=Csk [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	450 amino acids
Gene Ontology:
Cellular Component:	cell-cell junction [UNKNOWN][IEA] cytoplasm [IEA] cytosol [UNKNOWN] plasma membrane [UNKNOWN][IEA]
Biological Process:	negative regulation of cell proliferation [UNKNOWN][IEA] protein amino acid phosphorylation [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [UNKNOWN][IEA] non-membrane spanning protein tyrosine kinase activity [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAIQASWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII  60
   61 PANYVQKREG VKAGTKLSLM PWFHGKITRE QAERLLYPPE TGLFLVREST NYPGDYTLCV 120
  121 SCEGKVEHYR IMYHASKLSI DEEVYFENLM QLVEHYTTDA DGLCTRLIKP KVMEGTVAAQ 180
  181 DEFYRSGWAL NMKELKLLQT IGKGEFGDVM LGDYRGNKVA VKCIKNDATA QAFLAEASVM 240
  241 TQLRHSNLVQ LLGVIVEEKG GLYIVTEYMA KGSLVDYLRS RGRSVLGGDC LLKFSLDVCE 300
  301 AMEYLEGNNF VHRDLAARNV LVSEDNVAKV SDFGLTKEAS STQDTGKLPV KWTAPEALRE 360
  361 KKFSTKSDVW SFGILLWEIY SFGRVPYPRI PLKDVVPRVE KGYKMDAPDG CPPAVYDVMK 420
  421 NCWHLDAATR PTFLQLREQL EHIRTHELHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: CSK_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: