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Protein Overview: PLD2_RAT

General Information:
Name(s) found: PLD2_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Phospholipase D2 OS=Rattus norvegicus GN=Pld2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 933 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    caveola [IDA]
    brush border membrane [UNKNOWN]
    sarcolemma [IDA]
    Golgi apparatus [IDA]
    plasma membrane [UNKNOWN][IDA]
    lamellipodium [IDA]
    Biological Process: positive regulation of mast cell degranulation [IMP]
    positive regulation of phosphoinositide 3-kinase cascade [IMP]
    cell communication [IEA]
    neuron projection development [IMP]
    metabolic process [IEA]
    phospholipid catabolic process [IMP]
    G-protein coupled receptor internalization [UNKNOWN]
    response to organic cyclic substance [IDA]
    response to hydrogen peroxide [IMP]
    positive regulation of cell adhesion [IMP]
    receptor-mediated endocytosis [UNKNOWN]
    response to peptide hormone stimulus [IMP]
    response to hypoxia [IDA]
    lipid catabolic process [IEA]
    positive regulation of receptor-mediated endocytosis [IMP]
    positive regulation of cell migration [IMP]
    Molecular Function: protein kinase C binding [IPI]
    protein binding [UNKNOWN][IEA][IPI]
    catalytic activity [IEA]
    phosphoinositide binding [IEA]
    phospholipase D activity [IDA]
    NAPE-specific phospholipase D activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTQTDLFP YGDYLNSSQL HMEPDVVDTL KEGEDPADRM HPFLAIYDLQ PLRAHPLVFA  60
   61 PGVPVIAQVV GTERYTSGSK VGTCTLYSVR LTHGDFTWTT KKKFRHFQEL HRDLQRHKVL 120
  121 MSLLNLARFA AAHSPAREAA NENIPSLPRG GSEGSARHTA SKQKYLENYL NRLLTMSFYR 180
  181 NYHAMTEFLE VSQLSFIPDL GSKGLEGVIR KRSGGHRVPG FTCCGRDQVC YRWSKRWLVV 240
  241 KDSFLLYMRP ETGAISFVQL FDPGFEVQVG KRSTEARYGV RIDTSHRSLI LKCSSYRQAR 300
  301 WWGQEITELA QGPGRDFLQL HQHDSYAPPR PGTLARWFVN GAGYFAAVAD AILRAREEIF 360
  361 ITDWWLSPEI YLKRPAHSDD WRLDIMLKRK AEEGVRVSIL LFKEVELALG INSGYSKRTL 420
  421 MLLHPNIKVM RHPDLVTLWA HHEKLLVVDQ AVAFLGGLDL AYGRWDDVQY RLTDLGDPSE 480
  481 SADSQTPTPG SDPAATPDLS HNHFFWLGKD YSNLITKDWV QLDRPFEDFI DRETTPRMPW 540
  541 RDVGVVVHGV AARDLARHFI QRWNFTKTIK ARYKIPQYPY LLPKSASTAN HLPFIIPGGQ 600
  601 CATVQVLRSV DRWSAGTLES SILNAYLHTI RESQHFLYIE NQFFISCSDG RTVLNKVGDE 660
  661 IVDRILKAHE QGQCFRVYVL LPLLPGFEGD ISTGGGNSIQ AILHFTYRTL CRGEYSILHR 720
  721 LKAAMGTAWR DYMSICGLRT HGELGGHPIS ELIYIHSKLL IADDRTVIIG SANINDRSLL 780
  781 GKRDSELAIL IKDTEMEPSL MDGVEYQAGR FALSLRGRCF SVILGANTWP DLDLRDPVCD 840
  841 DFFQLWQETA ENNATIYEQI FRCLPSNATR SLRALREYVA VESLATVSPS LAQSELAHIR 900
  901 GHLVHFPLKF LEDESLLPHW GAKRGMIPLE VWT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle