Protein Overview: ACSL6_RAT

General Information:
Name(s) found:	ACSL6_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JX0205 long-chain-fatty-acid-CoA ligase (EC 6.2.1.3), brain [validated] - rat [NCBI NR] gi\|417242\|sp\|P33124.1\|ACSL6_RAT RecName: Full=Long-chain-fatty-acid--CoA ligase 6; AltName: Full=Long-chain acyl-CoA synthetase 6; Short=LACS 6; AltName: Full=Long-chain-fatty-acid--CoA ligase, brain isozyme [NCBI NR] gi\|217755\|dbj\|BAA00932.1\| long-chain acyl-CoA synthetase [Rattus norvegicus] [NCBI NR] gi\|149052614\|gb\|EDM04431.1\| acyl-CoA synthetase long-chain family member 6, isoform CRA_d [Rattus norvegicus] [NCBI NR] (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) [Swiss-Prot] Long-chain-fatty-acid--CoA ligase 6 OS=Rattus norvegicus GN=Acsl6 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None Long-chain-fatty-acid--CoA ligase 6 [hmr_yeast5_DM3-1_pombe.fasta] long-chain-fatty-acid-CoA ligase (EC 6.2.1.3), brain [validated] - ratgi\|217755\|dbj\|BAA00932.1\| long-chain acyl-CoA synthetase [Rattus norvegicus]gi\|417242\|sp\|P33124\|LCF6_RAT Long-chain-fatty-acid--CoA ligase 6 (Long-chain acyl-CoA synthetase 6) (LACS 6 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Long-chain-fatty-acid--CoA ligase 6 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Long-chain-fatty-acid--CoA ligase 6 (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] long-chain acyl-CoA synthetase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] acyl-CoA synthetase long-chain family member 6, isoform CRA_d [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 LONG-CHAIN-FATTY-ACID--COA LIGASE 6 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Acsl6 Long-chain-fatty-acid--CoA ligase 6 [rat-ipi-250309-contam.fasta] Isoform 1 of Long-chain-fatty-acid--CoA ligase 6 OS=Rattus norvegicus GN=Acsl6 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	697 amino acids
Gene Ontology:
Cellular Component:	peroxisomal membrane [IEA] endoplasmic reticulum membrane [IEA] nucleus [IDA] peroxisome [IEA] mitochondrion [UNKNOWN][IEA] membrane [IEA] microsome [IEA] integral to membrane [IEA] endoplasmic reticulum [IEA] mitochondrial outer membrane [IEA]
Biological Process:	metabolic process [IEA] phospholipid biosynthetic process [IMP] triglyceride metabolic process [IGI] response to nutrient [IEP] response to steroid hormone stimulus [IEP] neuron development [IEP] cellular response to insulin stimulus [IEP] response to gravity [IEP] long-chain fatty acid metabolic process [IDA] neuroblast proliferation [UNKNOWN] response to hypoxia [IEP] positive regulation of plasma membrane long-chain fatty acid transport [IMP] fatty acid transport [IGI] positive regulation of triglyceride biosynthetic process [IGI] lipid metabolic process [IEA] positive regulation of neuron projection development [IMP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [UNKNOWN] catalytic activity [IEA] long-chain fatty acid-CoA ligase activity [UNKNOWN][IDA][IGI] ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTQEILRIL RLPELSDLGQ FFRSLSATTL VSMGALAAIL AYWLTHRPKA LQPPCNLLMQ  60
   61 SEEVEDSGGA RRSVIGDCTQ LLTHYYDDAR TMYQVFRRGL SISGNGPCLG FRKPEQPYQW 120
  121 LSYQEVAKRA EFLGSGLLQH DCKVGTEQFI GVFAQNRPEW IIAELACYTY SMVVVPLYDT 180
  181 LGPGSIRYII NTADICTVIV DKPHKAILLL EHVERKETPG LKLVILMEPF DDALRERGKK 240
  241 CGVDIKSMQA IEDSGQENHR VPVPPRPDDL SIVCFTSGTT GNPKGAMLTH GNVVADFSGF 300
  301 LKVTESQWAP TCADVHFSYL PLAHMFERMV QSVVYCHGGR VGFFQGDIRL LSDDMKALRP 360
  361 TIFPVVPRLL NRMYDKIFHQ ADTSLKRWLL EFAAKRKQAE VRSGIIRNNS IWDELFFNKI 420
  421 QASLGGHVRM IVTGAAPASP TVLGFLRAAL GCQVYEGYGQ TECTAGCTFT TPGDWTSGHV 480
  481 GAPLPCNHIK LVDAEELNYW TSKGEGEICV KGPNVFKGYL KDEDRTKEAL DSDGWLHTGD 540
  541 IGKWLPEGTL KIIDRKKHIF KLAQGEYVAP EKIENIYIRS EPVAQIYVHG DSLKAFLVGI 600
  601 VVPDPEVMPC WAQKKGIEGN YQELCKSKEL KKAILDDMVM LGKESGLHSF EQVKAIYIHC 660
  661 DMFSVQNGLL TPTLKAKRPE LREYFKKQIE ELYSISM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACSL6_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: