Protein Overview: SC6A3_RAT

General Information:
Name(s) found:	SC6A3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|7106413\|ref\|NP_036826.1\| solute carrier family 6, member 3 [Rattus norvegicus] [NCBI NR] gi\|310098\|gb\|AAA73143.1\| [Rat dopamine transporter mRNA, complete cds.], gene product [NCBI NR] pir\|\|I59558 dopamine transporter - rat [NCBI NR] gi\|203981\|gb\|AAA41100.1\| dopamine transporter [NCBI NR] gi\|149032798\|gb\|EDL87653.1\| solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [Rattus norvegicus] [NCBI NR] gi\|128613\|sp\|P23977.1\|SC6A3_RAT RecName: Full=Sodium-dependent dopamine transporter; Short=DA transporter; Short=DAT; AltName: Full=Solute carrier family 6 member 3 [NCBI NR] Sodium-dependent dopamine transporter OS=Rattus norvegicus GN=Slc6a3 PE=2 SV=1 [Swiss-Prot] (P23977) Sodium-dependent dopamine transporter (DA transporter) (DAT) [Swiss-Prot] Ensembl_locations(Chr-bp):Un-21024672 Sodium-dependent dopamine transporter [hmr_yeast5_DM3-1_pombe.fasta] solute carrier family 6, member 3; Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Solute carrier family 6 (neurotransmitter transporter dopamine) member 3 [HMR_022704-rand.fasta] solute carrier family 6, member 3 [Rattus norvegicus]gi\|128613\|sp\|P23977\|S6A3_RAT Sodium-dependent dopamine transporter (DA transporter) (DAT)gi\|2119588\|pir\|\|I59558 dopamine transporter - ratgi\|310098\|gb\|AAA73143.1\| [Rat dopamine transporter mRNA, comp [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Sodium-dependent dopamine transporter [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012694) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Sodium-dependent dopamine transporter (DA transporter) (DAT) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] solute carrier family 6, member 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] [Rat dopamine transporter mRNA, complete cds.], gene product [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopamine transporter [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SODIUM-DEPENDENT DOPAMINE TRANSPORTER [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Slc6a3 Sodium-dependent dopamine transporter [rat-ipi-250309-contam.fasta] Sodium-dependent dopamine transporter OS=Rattus norvegicus GN=Slc6a3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	619 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA] synaptosome [IDA] plasma membrane [UNKNOWN][IDA]
Biological Process:	dopamine biosynthetic process [UNKNOWN][IEA] dopamine transport [UNKNOWN][IDA] prepulse inhibition [UNKNOWN][IEA] adenohypophysis development [UNKNOWN][IEA] response to cocaine [UNKNOWN][IEA] response to cAMP [IDA] lactation [UNKNOWN][IEA] dopamine catabolic process [UNKNOWN][IEA] response to organic cyclic substance [IEP] response to nicotine [IEP] aging [IEP] positive regulation of multicellular organism growth [UNKNOWN][IEA] neurotransmitter transport [IEA] response to ethanol [IDA] locomotory behavior [UNKNOWN][IEA] regulation of dopamine metabolic process [UNKNOWN][IEA] response to drug [IEP] sensory perception of smell [UNKNOWN][IEA] response to iron ion [IEP] monoamine transport [UNKNOWN][IEA]
Molecular Function:	dopamine transmembrane transporter activity [UNKNOWN] protein binding [UNKNOWN] drug binding [IDA] dopamine binding [UNKNOWN][IEA] protein N-terminus binding [IEA] dopamine:sodium symporter activity [IDA] symporter activity [IEA] monoamine transmembrane transporter activity [UNKNOWN] protein complex binding [IDA] receptor binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSKCSVGP MSSVVAPAKE SNAVGPREVE LILVKEQNGV QLTNSTLINP PQTPVEAQER  60
   61 ETWSKKIDFL LSVIGFAVDL ANVWRFPYLC YKNGGGAFLV PYLLFMVIAG MPLFYMELAL 120
  121 GQFNREGAAG VWKICPVLKG VGFTVILISF YVGFFYNVII AWALHYFFSS FTMDLPWIHC 180
  181 NNTWNSPNCS DAHASNSSDG LGLNDTFGTT PAAEYFERGV LHLHQSRGID DLGPPRWQLT 240
  241 ACLVLVIVLL YFSLWKGVKT SGKVVWITAT MPYVVLTALL LRGVTLPGAM DGIRAYLSVD 300
  301 FYRLCEASVW IDAATQVCFS LGVGFGVLIA FSSYNKFTNN CYRDAIITTS INSLTSFSSG 360
  361 FVVFSFLGYM AQKHNVPIRD VATDGPGLIF IIYPEAIATL PLSSAWAAVF FLMLLTLGID 420
  421 SAMGGMESVI TGLVDEFQLL HRHRELFTLG IVLATFLLSL FCVTNGGIYV FTLLDHFAAG 480
  481 TSILFGVLIE AIGVAWFYGV QQFSDDIKQM TGQRPNLYWR LCWKLVSPCF LLYVVVVSIV 540
  541 TFRPPHYGAY IFPDWANALG WIIATSSMAM VPIYATYKFC SLPGSFREKL AYAITPEKDH 600
  601 QLVDRGEVRQ FTLRHWLLL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SC6A3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: