Protein Overview: RYK_MOUSE

General Information:
Name(s) found:	RYK_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|598329\|gb\|AAA67060.1\| receptor tyrosine kinase-related protein [NCBI NR] gi\|547811\|sp\|Q01887.2\|RYK_MOUSE RecName: Full=Tyrosine-protein kinase RYK; AltName: Full=Kinase VIK; AltName: Full=NYK-R; AltName: Full=Met-related kinase; Flags: Precursor [NCBI NR] pir\|\|I56248 receptor tyrosine kinase-related protein - mouse [NCBI NR] gi\|202440\|gb\|AAA40579.1\| tyrosine kinase-related protein [NCBI NR] gi\|110681700\|ref\|NP_038677.3\| receptor-like tyrosine kinase isoform 1 [Mus musculus] [NCBI NR] Tyrosine-protein kinase RYK OS=Mus musculus GN=Ryk PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):9-102898239 Tyrosine-protein kinase RYK precursor [hmr_yeast5_DM3-1_pombe.fasta] Tyrosine-protein kinase RYK precursor [ipi.MOUSE.v3.06.fasta] Tyrosine-protein kinase RYK precursor (Kinase VIK) (NYK-R) (Met-related kinase)gi\|2137725\|pir\|\|I56248 receptor tyrosine kinase-related protein - mousegi\|598329\|gb\|AAA67060.1\| receptor tyrosine kinase-related proteingi\|202440\|gb\|AAA40579.1\| tyrosine kin [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Tyrosine-protein kinase RYK precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] receptor-like tyrosine kinase isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_03-19-2007_reversed.fasta] Tyrosine-protein kinase RYK precursor (Kinase VIK) (NYK-R) (Met-related kinase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] receptor tyrosine kinase-related protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tyrosine kinase-related protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 TYROSINE-PROTEIN KINASE RYK PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Ryk Tyrosine-protein kinase RYK [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Ryk Tyrosine-protein kinase RYK precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Ryk Tyrosine-protein kinase RYK precursor ENSMUSG00000032547 IPI00128580 IPI00752203 [IPIxENS.MOUSE_plus_REVERSE.fasta] tyrosine-protein kinase RYK isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00128580.1\|SWISS-PROT:Q01887\|ENSEMBL:ENSMUSP00000035142\|REFSEQ:NP_038677 Tax_Id=10090 Gene_Symbol=Ryk Tyrosine-protein kinase RYK [ipi.MOUSE.fasta.20090209] Tyrosine-protein kinase RYK OS=Mus musculus GN=Ryk [011711_HMR.fasta] Tyrosine-protein kinase RYK OS=Mus musculus GN=Ryk PE=2 SV=2 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] sp\|Q01887\|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus GN=Ryk PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	594 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] integral to plasma membrane [IEA] membrane [IDA] integral to membrane [IEA] plasma membrane [IDA]
Biological Process:	negative chemotaxis [IGI] axonogenesis [IGI] Wnt receptor signaling pathway [IGI] negative regulation of axon extension involved in axon guidance [IGI] protein amino acid phosphorylation [IEA] skeletal system morphogenesis [IMP] commissural neuron axon guidance [IMP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] [NOT]protein tyrosine kinase activity [IDA] Wnt receptor activity [IPI] protein binding [IPI] transmembrane receptor protein tyrosine kinase activity [IEA] protein kinase activity [IEA] Wnt-protein binding [IPI] transferase activity [IEA] receptor activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAGRGGVPG SGGLRAPPPP LLLLLLAMLP AAAPRSPALA AAPAGPSVSL YLSEDEVRRL  60
   61 LGLDAELYYV RNDLISHYAL SFNLLVPSET NFLHFTWHAK SKVEYKLGFQ VDNFVAMGMP 120
  121 QVNISAQGEV PRTLSVFRVE LSCTGKVDSE VMILMQLNLT VNSSKNFTVL NFKRRKMCYK 180
  181 KLEEVKTSAL DKNTSRTIYD PVHAAPTTST RVFYISVGVC CAVIFLVAII LAVLHLHSMK 240
  241 RIELDDSISA SSSSQGLSQP STQTTQYLRA DTPNNATPIT SSSGYPTLRI EKNDLRSVTL 300
  301 LEAKAKVKDI AISRERITLK DVLQEGTFGR IFHGILVDEK DPNKEKQTFV KTVKDQASEV 360
  361 QVTMMLTESC KLRGLHHRNL LPITHVCIEE GEKPMVVLPY MNWGNLKLFL RQCKLVEANN 420
  421 PQAISQQDLV HMAIQIACGM SYLARREVIH RDLAARNCVI DDTLQVKITD NALSRDLFPM 480
  481 DYHCLGDNEN RPVRWMALES LVNNEFSSAS DVWAFGVTLW ELMTLGQTPY VDIDPFEMAA 540
  541 YLKDGYRIAQ PINCPDELFA VMACCWALDP EERPKFQQLV QCLTEFHAAL GAYV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: RYK_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: