Protein Overview: S12A3_MOUSE

General Information:
Name(s) found:	S12A3_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|27151683\|sp\|P59158.1\|S12A3_MOUSE RecName: Full=Solute carrier family 12 member 3; AltName: Full=Thiazide-sensitive sodium-chloride cotransporter; AltName: Full=Na-Cl symporter [NCBI NR] gi\|26342883\|dbj\|BAC35098.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|24047306\|gb\|AAH38612.1\| Solute carrier family 12, member 3 [Mus musculus] [NCBI NR] Solute carrier family 12 member 3 OS=Mus musculus GN=Slc12a3 PE=1 SV=1 [Swiss-Prot] (P59158) Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter) [Swiss-Prot] Ensembl_locations(Chr-bp):8-93695824 Solute carrier family 12 member 3 [hmr_yeast5_DM3-1_pombe.fasta] Solute carrier family 12, member 3 [Mus musculus]gi\|26342883\|dbj\|BAC35098.1\| unnamed protein product [Mus musculus]gi\|27151683\|sp\|P59158\|S123_MOUSE Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter) [nrdb_11152004_Chlamydomonas] Solute carrier family 12, member 3 [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Solute carrier family 12 member 3 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10090 Solute carrier family 12, member 3 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Solute carrier family 12, member 3 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SOLUTE CARRIER FAMILY 12 MEMBER 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Slc12a3 Solute carrier family 12 member 3 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Slc12a3 Solute carrier family 12 member 3 ENSMUSG00000031766 IPI00173140 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00173140.1\|SWISS-PROT:P59158\|TREMBL:Q543E4;Q62439\|ENSEMBL:ENSMUSP00000034218\|REFSEQ:NP_062288 Tax_Id=10090 Gene_Symbol=Slc12a3 Solute carrier family 12 member 3 [ipi.MOUSE.fasta.20090209] Solute carrier family 12 member 3 OS=Mus musculus GN=Slc12a3 [011711_HMR.fasta] Solute carrier family 12 member 3 OS=Mus musculus GN=Slc12a3 PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] sp\|P59158\|S12A3_MOUSE Solute carrier family 12 member 3 OS=Mus musculus GN=Slc12a3 PE=1 SV=1 [uniprot.sptr.mouse.20130102] tr\|Q543E4\|Q543E4_MOUSE Putative uncharacterized protein OS=Mus musculus GN=Slc12a3 PE=2 SV=1 [uniprot.sptr.mouse.20130102] Putative uncharacterized protein OS=Mus musculus GN=Slc12a3 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Isoform of P59158, Solute carrier family 12 member 3 OS=Mus musculus GN=Slc12a3 PE=1 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	1002 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] vesicle [UNKNOWN] cytosol [IDA] apical plasma membrane [UNKNOWN][IDA] plasma membrane [IDA]
Biological Process:	sodium ion transport [UNKNOWN][IMP] ion transport [IEA] transmembrane transport [IEA] transport [IEA] chloride transport [UNKNOWN]
Molecular Function:	sodium:chloride symporter activity [UNKNOWN] cation:chloride symporter activity [IEA] symporter activity [IEA] transporter activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELPVTELP GDALCSGRFT ISTLMGGDEP PPAACDSSQP SHLTHGSTLY MRTFGYNTID  60
   61 VVPAYEHYAN SALPGEPRKV RPTLADLHSF LKQEGSHLHA LAFDGRQGRE LTDGLVEDET 120
  121 GTNSEKSPGE PVRFGWVKGV MIRCMLNIWG VILYLRLPWI TAQAGIVLTW LIILLSVMVT 180
  181 SITGLSISAI STNGKVKSGG TYFLISRSLG PELGGSIGLI FAFANAVGVA MHTVGFAETV 240
  241 RDLLQEYGTP IVDPINDIRI IGVVTVTVLL AISLAGMEWE SKAQVLFFLV IMVSFANYLV 300
  301 GTLIPASEDK ASKGFYSYHG DIFVQNLVPD WRGIDGSFFG MFSIFFPSAT GILAGANISG 360
  361 DLKDPAVAIP KGTLMAIFWT TISYLAISAT IGSCVVRDAS GDVNDTMTPG PGPCEGLACG 420
  421 YGWNFTECSQ QRSCRYGLIN YYQTMSMVSA FAPLITAGIF GATLSSALAC LVSAAKVFQC 480
  481 LCEDQLYPLI GFFGKGYGKN REPVRGYLLA YAIAVAFIII AELNTIAPII SNFFLCSYAL 540
  541 INFSCFHASI TNSPGWRPSF RYYSKWAALF GAVISVVIMF LLTWWAALIA IGVVLFLLLY 600
  601 VIYKKPEVNW GSSVQAGSYN LALSYSVGLN EVEDHIKNYR PQCLVLTGPP NFRPALVDFV 660
  661 STFTQNLSLM ICGHVLIGPG KQRVPELRLI ASGHTKWLNK RKIKAFYSDV IAEDLRSGVQ 720
  721 ILMQASGLGR MKPNILVVGF KRNWQSAHPA TVEDYIGVLH DAFDFNYGVC VMRMREGLNV 780
  781 SEALQTHTTP EALIQEEQAS TIFQSEQGKK TIDIYWLFDD GGLTLLIPYL LHRKKRWGKC 840
  841 KIRVFVGGQI NRMDEERKAI ISLLSKFRLG FHEVHVLPDI NQKPQAEHTK RFEDMIAPFR 900
  901 LNDGFKDEAT VTEMRRDCPW KISDEEINKN RIKSLRQVRL SEILLDYSRD AALIILTLPI 960
  961 GRKGKCPSSL YMAWLETLSQ DLRPPVLLIR GNQENVLTFY CQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: S12A3_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: