Protein Overview: PGCA_MOUSE

General Information:
Name(s) found:	PGCA_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6671523\|ref\|NP_031450.1\| aggrecan 1 [Mus musculus] [NCBI NR] gi\|2497650\|sp\|Q61282.1\|PGCA_MOUSE RecName: Full=Aggrecan core protein; AltName: Full=Cartilage-specific proteoglycan core protein; Short=CSPCP; Flags: Precursor [NCBI NR] gi\|191772\|gb\|AAC37670.1\| aggrecan [NCBI NR] pir\|\|A55182 aggrecan precursor - mouse [NCBI NR] Aggrecan core protein OS=Mus musculus GN=Acan PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):7-67381888 Aggrecan core protein precursor [hmr_yeast5_DM3-1_pombe.fasta] aggrecan 1; aggrecan, structural proteoglycan of cartilage; cartilage matrix deficiency [HMR_022704-rand.fasta] Aggrecan core protein precursor [ipi.MOUSE.v3.06.fasta] aggrecan 1 [Mus musculus]gi\|2497650\|sp\|Q61282\|PGCA_MOUSE Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP)gi\|1083206\|pir\|\|A55182 aggrecan precursor - mousegi\|191772\|gb\|AAC37670.1\| aggrecan [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Aggrecan core protein precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_007424) aggrecan 1; aggrecan, structural proteoglycan of cartilage; cartilage matrix deficiency [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] aggrecan 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aggrecan [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 AGGRECAN CORE PROTEIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Acan Aggrecan core protein [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Acan Aggrecan core protein precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Acan Aggrecan core protein precursor ENSMUSG00000030607 IPI00119035 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00119035.1\|SWISS-PROT:Q61282\|ENSEMBL:ENSMUSP00000032835\|REFSEQ:NP_031450 Tax_Id=10090 Gene_Symbol=Acan Aggrecan core protein [ipi.MOUSE.fasta.20090209] Aggrecan core protein OS=Mus musculus GN=Acan [011711_HMR.fasta]
Organism:	Mus musculus
Length:	2132 amino acids
Gene Ontology:
Cellular Component:	basement membrane [IDA] glycoprotein network [UNKNOWN] extracellular matrix [IDA] extracellular region [IEA] proteinaceous extracellular matrix [UNKNOWN][IDA]
Biological Process:	cartilage condensation [IMP] chondrocyte development [IMP] cell adhesion [IEA] collagen fibril organization [IMP] proteoglycan biosynthetic process [IMP] negative regulation of cell migration [UNKNOWN]
Molecular Function:	protein binding [IPI] sugar binding [IEA] calcium ion binding [UNKNOWN] hyaluronic acid binding [IEA] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTLLLVFVT LRVIAAVISE EVPDHDNSLS VSIPQPSPLK VLLGSSLTIP CYFIDPMHPV  60
   61 TTAPSTAPLT PRIKWSRVSK EKEVVLLVAT EGQVRVNSIY QDKVSLPNYP AIPSDATLEI 120
  121 QNLRSNDSGI YRCEVMHGIE DSEATLEVIV KGIVFHYRAI STRYTLDFDR AQRACLQNSA 180
  181 IIATPEQLQA AYEDGFHQCD AGWLADQTVR YPIHTPREGC YGDKDEFPGV RTYGIRDTNE 240
  241 TYDVYCFAEE MEGEVFYATS PEKFTFQEAA NECRRLGARL ATTGQLYLAW QGGMDMCSAG 300
  301 WLADRSVRYP ISKARPNCGG NLLGVRTVYL HANQTGYPDP SSRYDAICYT GEDFVDIPEN 360
  361 FFGVGGEDDI TIQTVTWPDL ELPLPRNVTE GEALGSVILT AKPIFDLSPT ISEPGEALTL 420
  421 APEVGSTAFP EAEERTGEAT RPWGFPAEVT RGPDSATAFA SEDLVVRVTI SPGAAEVPGQ 480
  481 PHLPGGVVFH YRPGSTRYSL TFEEAQQACM HTGAIIASPE QLQAAYEAGY EQCDAGWLQD 540
  541 QTVRYPIVSP RTPCVGDKDS SPGVRTYRVR PSSETYDVYC YVDKLEGEVF FATRLEQFTF 600
  601 QEARAFCAAQ NATLASTGQL YAAWSQGLDK CYAGWLADGT LRYPIITPRP ACGGDKPGVR 660
  661 TVYLYPNQTG LPDPLSKHHA FCFRGVSVAP SPGEEEGSTP TSPSDIEDWI VTQVGPGVDA 720
  721 VPLEPKTTEV PYFTTEPRKQ TEWEPAYTPV GTSPQPGIPP TWLPTLPAAE EHTESPSASE 780
  781 EPSASAVPST SEEPYTSSFA VPSMTELPGS GEASGAPDLS GDFTGSGDAS GRLDSSGQPS 840
  841 GGIESGLPSG DLDSSGLSPT VSSGLPVESG SASGDGEVPW SHTPTVGRLP SGGESPEGSA 900
  901 SASGTGDLSG LPSGGEITET STSGAEETSG LPSGGDGLET STSGVDDVSG IPTGREGLET 960
  961 SASGVEDLSG LPSGEEGSET STSGIEDISV LPTGGESLET SASGVGDLSG LPSGGESLET1020
 1021 SASGAEDVTQ LPTERGGLET SASGVEDITV LPTGRESLET SASGVEDVSG LPSGREGLET1080
 1081 SASGIEDISV FPTEAEGLDT SASGGYVSGI PSGGDGTETS ASGVEDVSGL PSGGEGLETS1140
 1141 ASGVEDLGPS TRDSLETSAS GVDVTGFPSG RGDPETSVSG VGDDFSGLPS GKEGLETSAS1200
 1201 GAEDLSGLPS GKEDLVGSAS GALDFGKLPP GTLGSGQTPE VNGFPSGFSG EYSGADIGSG1260
 1261 PSSGLPDFSG LPSGFPTVSL VDSTLVEVIT ATTSSELEGR GTIGISGSGE VSGLPLGELD1320
 1321 SSADISGLPS GTELSGQASG SPDSSGETSG FFDVSGQPFG SSGVSEETSG IPEISGQPSG1380
 1381 TPDTTATSGV TELNELSSGQ PDVSGDGSGI LFGSGQSSGI TSVSGETSGI SDLSGQPSGF1440
 1441 PVFSGTATRT PDLASGTISG SGESSGITFV DTSFVEVTPT TFREEEGLGS VELSGFPSGE1500
 1501 TELSGTSGTV DVSEQSSGAI DSSGLTSPTP EFSGLPSGVA EVSGEFSGVE TGSSLPSGAF1560
 1561 DGSGLVSGFP TVSLVDRTLV ESITQAPTAQ EAGEGPSGIL EFSGAHSGTP DISGELSGSL1620
 1621 DLSTLQSGQM ETSTETPSSP YFSGDFSSTT DVSGESIAAT TGSGESSGLP EVTLNTSELV1680
 1681 EGVTEPTVSQ ELGHGPSMTY ISRLSEASGD ASASGDLGGA VTNFPGSGVE ASVPEASSDL1740
 1741 SAYPEAGVGV SAAPEASSKL SEFPDLHGIT SAFHETDLEM TTPSTEVNSN PWTFQEGTRE1800
 1801 GSAAPEVSGE SSTTSDIDTG TSGVPSATPM ASGDRTEISG EWSDHTSEVN VAISSTITES1860
 1861 EWAQPTRYPT ETLQEIESPN PSYSGEETQT AETTMSLTDA PTLSSSEGSG ETESTVADQE1920
 1921 QCEEGWTKFQ GHCYRHFPDR ETWVDAERRC REQQSHLSSI VTPEEQEFVN KNAQDYQWIG1980
 1981 LNDRTIEGDF RWSDGHSLQF EKWRPNQPDN FFATGEDCVV MIWHERGEWN DVPCNYQLPF2040
 2041 TCKKGTVACG DPPVVEHART LGQKKDRYEI SSLVRYQCTE GFVQRHVPTI RCQPSGHWEE2100
 2101 PRITCTDPNT YKHRLQKRTM RPTRRSRPSM AH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PGCA_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: