Protein Overview: DEGS2_MOUSE

General Information:
Name(s) found:	DEGS2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81901526\|sp\|Q8R2F2.1\|DEGS2_MOUSE RecName: Full=Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; AltName: Full=Degenerative spermatocyte homolog 2 [NCBI NR] gi\|27754029\|ref\|NP_081575.2\| degenerative spermatocyte homolog 2, lipid desaturase [Mus musculus] [NCBI NR] gi\|20147518\|gb\|AAM12533.1\|AF466377_1 sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [Mus musculus] [NCBI NR] gi\|127798974\|gb\|AAH16427.2\| Degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase [Mus musculus] [NCBI NR] Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 OS=Mus musculus GN=Degs2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):12-102749547 Sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [hmr_yeast5_DM3-1_pombe.fasta] sphingolipid delta 4 desaturase/C-4 hydroxylase [HMR_022704-rand.fasta] Sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [ipi.MOUSE.v3.06.fasta] sphingolipid delta 4 desaturase/C-4 hydroxylase [Mus musculus]gi\|20147518\|gb\|AAM12533.1\| sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] sphingolipid delta 4 desaturase/C-4 hydroxylase [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 (Degenerative spermatocyte homolog 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] degenerative spermatocyte homolog 2, lipid desaturase [Mus musculus] [NCBI-RefSeq_mouse_na_04-07-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Degs2 Isoform 1 of Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Degs2 Sphingolipid delta 4 desaturase/C-4 hydroxylase protein DES2 [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Degs2 Isoform 1 of Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 ENSMUSG00000021263 IPI00172135 IPI00877336 [IPIxENS.MOUSE_plus_REVERSE.fasta] sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00172135.1\|SWISS-PROT:Q8R2F2-1\|ENSEMBL:ENSMUSP00000021691\|REFSEQ:NP_081575 Tax_Id=10090 Gene_Symbol=Degs2 Isoform 1 of Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 [ipi.MOUSE.fasta.20090209] Isoform 1 of Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 OS=Mus musculus GN=Degs2 [011711_HMR.fasta] Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 OS=Mus musculus GN=Degs2 PE=1 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] sp\|Q8R2F2\|DEGS2_MOUSE Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 OS=Mus musculus GN=Degs2 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	323 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] endoplasmic reticulum [IEA] cellular_component [ND]
Biological Process:	lipid metabolic process [IEA] lipid biosynthetic process [IEA] ceramide biosynthetic process [IDA] oxidation reduction [IEA] fatty acid biosynthetic process [IEA] sphinganine metabolic process [IDA][IGI] sphingolipid biosynthetic process [IGI]
Molecular Function:	oxidoreductase activity [IEA] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEA] sphingolipid delta-4 desaturase activity [IGI] sphingosine hydroxylase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNSAARSDF EWVYSDQPHT QRRKEMLAKY PAIKALMRPD PHIKWTVSGM VLVQVLACWL  60
   61 VRGLSWRWLL FWAYAFGGCI NHSLTLAIHD ISHNTAFGTS CVSRNRWFAI FANLPIGLPY 120
  121 ATSFKKYHVD HHRYLGGDGL DVDIPTNFEG WFFCTPARKL LWLVLQPFFY SLRPLCVNPK 180
  181 VVTRMEILNA LVQLAFDVTI FALWGIKPIV YLLGSSLLGL GLHPISGHFV AEHYMFLKGH 240
  241 ETYSYYGPLN WITFNVGYHM EHHDFPSIPG YYLPLVRKIA PEYYDHLPQH HSWVKVLWDF 300
  301 VFEDSMGPYS RVKRKCKLAK DHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: DEGS2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: