Protein Overview: OPLA_MOUSE

General Information:
Name(s) found:	OPLA_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|27923825\|sp\|Q8K010.1\|OPLA_MOUSE RecName: Full=5-oxoprolinase; AltName: Full=5-oxo-L-prolinase; Short=5-OPase; AltName: Full=Pyroglutamase [NCBI NR] gi\|23346557\|ref\|NP_694762.1\| 5-oxoprolinase (ATP-hydrolysing) [Mus musculus] [NCBI NR] gi\|21961483\|gb\|AAH34522.1\| 5-oxoprolinase (ATP-hydrolysing) [Mus musculus] [NCBI NR] gi\|148697596\|gb\|EDL29543.1\| 5-oxoprolinase (ATP-hydrolysing) [Mus musculus] [NCBI NR] 5-oxoprolinase OS=Mus musculus GN=Oplah PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):15-76527005 5-oxoprolinase [hmr_yeast5_DM3-1_pombe.fasta] 5-oxoprolinase (ATP-hydrolysing) [HMR_022704-rand.fasta] 5-oxoprolinase (ATP-hydrolysing) [Mus musculus]gi\|21961483\|gb\|AAH34522.1\| 5-oxoprolinase (ATP-hydrolysing) [Mus musculus]gi\|27923825\|sp\|Q8K010\|OPLA_MOUSE 5-oxoprolinase (5-oxo-L-prolinase) (Pyroglutamase) (5-OPase) [nrdb_11152004_Chlamydomonas] 5-oxoprolinase [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 5-oxoprolinase [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] 5-oxoprolinase (ATP-hydrolysing) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] 5-oxoprolinase (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 5-OXOPROLINASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Oplah 5-oxoprolinase [mouse-ipi-250309-contam.fasta] 5-oxoprolinase (5-oxo-L-prolinase) (Pyroglutamase) (5-OPase) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Oplah 5-oxoprolinase ENSMUSG00000022562 IPI00169473 [IPIxENS.MOUSE_plus_REVERSE.fasta] 5-oxoprolinase [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00169473.1\|SWISS-PROT:Q8K010\|TREMBL:Q3TPB5;Q3TYS9\|ENSEMBL:ENSMUSP00000023222\|REFSEQ:NP_694762 Tax_Id=10090 Gene_Symbol=Oplah 5-oxoprolinase [ipi.MOUSE.fasta.20090209] 5-oxoprolinase OS=Mus musculus GN=Oplah [011711_HMR.fasta] 5-oxoprolinase OS=Mus musculus GN=Oplah PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] sp\|Q8K010\|OPLA_MOUSE 5-oxoprolinase OS=Mus musculus GN=Oplah PE=2 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1288 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	glutathione metabolic process [ISS]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] catalytic activity [IEA] 5-oxoprolinase (ATP-hydrolyzing) activity [ISS] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSPEERFHF AIDRGGTFTD VFAQCPGGHV RVLKLLSEDP ANYADAPTEG IRRILEQERG  60
   61 VLLPRGRPLD TSHIASIRMG TTVATNALLE RQGERVALLV TRGFRDLLHI GTQARPDLFD 120
  121 LAVPMPEVLY EEVVEVDERV LLYRGEPGAG SPVKGCTGDL LEIQQPVDLA ALRGKLEGLL 180
  181 TRGIHSLAVV LMHSYTWAQH EQQVGTLARE LGFTHVSLSS EVMPMVRIVP RGHTACADAY 240
  241 LTPTIQRYVQ GFRRGFQGQL KNVQVLFMRS DGGLAPMDAF SGSRAVLSGP AGGVVGYSTT 300
  301 TYQLEGGQPV IGFDMGGTST DVSRYAGEFE HVFEASTAGV TLQAPQLDIN TVAAGGGSRL 360
  361 FFRSGLFVVG PESAGAHPGP ACYRKGGPVT VTDANLVLGR LLPASFPCIF GPGEDQPLSP 420
  421 EASRKALEAV AMEVNSFLAS GPCPASQLSL EEVAMGFVRV ANEAMCRPIR ALTQARGHDP 480
  481 SAHVLACFGG AGGQHACAIA RALGMDTVHI HRHSGLLSAL GLALADVVHE AQEPCSLSYT 540
  541 PETFAQLDQR LSRLEEQCVD ALQAQGFSRS QISTESFLHL RYQGTDCALM VSANQHPATT 600
  601 CSPRAGDFGA AFVERYMREF GFIIPERSVV VDDVRVRGTG RSGLQLEETS KIQSGPPHVE 660
  661 KVTQCYFEGG YQETPVYLLG ELGYGHQLQG PCLIIDNNST ILVEPGCQAE VIETGDIRIS 720
  721 VGAEAPSMID TKLDPIQLSI FSHRFMSIAE QMGRILQRTA ISTNIKERLD FSCALFGPDG 780
  781 GLVSNAPHIP VHLGAMQETV QFQIQHLGAD LHPGDVLLSN HPSAGGSHLP DLTVITPVFW 840
  841 PGQSRPVFYV ASRGHHADIG GITPGSMPPH STTLQQEGAV FLSFKLVQGG VFQEEAVTEA 900
  901 LQAPGKISGC SGTRNLHDNL SDLRAQVAAN QKGIQLVGEL IGQYGLDVVQ AYMGHIQANA 960
  961 ELAVRDMLRA FGTSRQARGL PLEVSAKDHM DDGSPICLHV QINLNQGSAV FDFSGSGSEV1020
 1021 FGNLNAPRAI TLSALIYCLR CLVGRDIPLN QGCLAPVQVI IPKGSILDPS PEAAVVGGNV1080
 1081 LTSQRVVDVI LGAFGACAAS QGCMNNVTLG NARMGYYETV AGGAGAGPGW HGRSGVHSHM1140
 1141 TNTRITDPEI LESRYPVILR RFELRPGSGG RGRFRGGDGV VRELVFREEA LLSVLTERRA1200
 1201 FQPYGLHGGE PGTRGLNLLI RKDGRTVNLG GKTSVTVYPG DAFCLHTPGG GGYGDPEDPA1260
 1261 PPPGSPPLYP AFPERGSVYE YRRAQEAV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.88

Protein Overview: OPLA_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: