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Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. Catalysis of the reaction: ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: 5-oxoprolinase (ATP-hydrolyzing) activity
Acc: GO:0017168
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate.
Synonyms:
  • pyroglutamic hydrolase activity
  • L-pyroglutamate hydrolase activity
  • pyroglutamase (ATP-hydrolysing)
  • 5-OPase activity
  • 5-oxo-L-prolinase activity
  • pyroglutamase (ATP-hydrolyzing) activity
  • pyroglutamase activity
  • 5-oxo-L-proline amidohydrolase (ATP-hydrolysing)
  • 5-oxoprolinase (ATP-hydrolysing)
  • oxoprolinase activity
  • pyroglutamate hydrolase activity
  • 5-oxoprolinase activity
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing) activity (interactive image map)

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