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Protein Overview: FGF4_MOUSE

General Information:
Name(s) found: FGF4_MOUSE [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Fibroblast growth factor 4 OS=Mus musculus GN=Fgf4 PE=2 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 202 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    Biological Process: cranial suture morphogenesis [IDA]
    embryonic limb morphogenesis [IGI]
    stem cell maintenance [IGI]
    positive regulation of cell division [IEA]
    cartilage condensation [IGI]
    negative regulation of apoptosis [IGI]
    positive regulation of gene expression [IDA]
    positive regulation of cell proliferation [UNKNOWN][IDA][IGI]
    fibroblast growth factor receptor signaling pathway [UNKNOWN][IGI]
    odontogenesis of dentine-containing tooth [IDA]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA][IGI]
    embryonic hindlimb morphogenesis [IGI]
    Molecular Function: growth factor activity [IEA]
    fibroblast growth factor receptor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRGPTTGT LLPRVLLALV VALADRGTAA PNGTRHAELG HGWDGLVARS LARLPVAAQP  60
   61 PQAAVRSGAG DYLLGLKRLR RLYCNVGIGF HLQVLPDGRI GGVHADTRDS LLELSPVQRG 120
  121 VVSIFGVASR FFVAMSSRGK LFGVPFFTDE CKFKEILLPN NYNAYEAYAY PGMFMALSKN 180
  181 GRTKKGNRVS PTMKVTHFLP RL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 43.522879 Fibroblast growth factor 4 (FGF4)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • growth factor activity
    		•  5.6790632853895 bayes_pls_golite062009
  • fibroblast growth factor receptor binding
    		•  5.32138222782692 bayes_pls_golite062009
  • receptor binding
    		•  4.8109037277027 bayes_pls_golite062009
  • cytokine activity
    		•  3.23273280319483 bayes_pls_golite062009
  • protein binding
    		•  2.73885234721265 bayes_pls_golite062009
  • binding
    		•  1.9997408351526 bayes_pls_golite062009
  • heparin binding
    		•  1.71092312487163 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.62267092567268 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.55309369051712 bayes_pls_golite062009
  • pattern binding
    		•  0.456311281248659 bayes_pls_golite062009
  • nerve growth factor receptor binding
    		•  0.308245352535379 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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