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Protein Overview: IL15_MOUSE

General Information:
Name(s) found: IL15_MOUSE [Swiss-Prot]
Description(s) found:
Found 32 descriptions.
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  • Interleukin-15 OS=Mus musculus GN=Il15 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 162 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IEA]
    extracellular region [IEA]
    Biological Process: regulation of T cell differentiation [IMP]
    extrathymic T cell selection [IMP]
    immune response [IEA]
    NK T cell proliferation [IMP]
    negative regulation of smooth muscle cell proliferation [UNKNOWN]
    regulation of defense response to virus by host [IMP]
    lymph node development [IMP]
    positive regulation of T cell proliferation [IMP]
    positive regulation of immune response [IMP]
    Molecular Function: cytokine activity [IMP]
    cytokine receptor binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILKPYMRN TSISCYLCFL LNSHFLTEAG IHVFILGCVS VGLPKTEANW IDVRYDLEKI  60
   61 ESLIQSIHID TTLYTDSDFH PSCKVTAMNC FLLELQVILH EYSNMTLNET VRNVLYLANS 120
  121 TLSSNKNVAE SGCKECEELE EKTFTEFLQS FIRIVQMFIN TS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..162] PSI-BLAST 39.30103 No description for 2z3qA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  5.3304255990112 bayes_pls_golite062009
  • cytokine activity
    		•  5.1883241815362 bayes_pls_golite062009
  • growth factor activity
    		•  4.92105782010612 bayes_pls_golite062009
  • cytokine receptor binding
    		•  4.4791226814754 bayes_pls_golite062009
  • protein binding
    		•  3.52041127390038 bayes_pls_golite062009
  • binding
    		•  2.95468228480505 bayes_pls_golite062009
  • interferon-alpha/beta receptor binding
    		•  2.26198409097082 bayes_pls_golite062009
  • interleukin-12 binding
    		•  2.17594406686308 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.52819399447638 bayes_pls_golite062009
  • signal transducer activity
    		•  1.52819399447638 bayes_pls_golite062009
  • hormone activity
    		•  1.36735241300603 bayes_pls_golite062009
  • interleukin-2 receptor binding
    		•  1.24568403220915 bayes_pls_golite062009
  • interleukin-10 receptor binding
    		•  1.11541468065738 bayes_pls_golite062009
  • interleukin-12 beta subunit binding
    		•  1.10825259714222 bayes_pls_golite062009
  • interleukin-6 receptor binding
    		•  1.10578552974983 bayes_pls_golite062009
  • interleukin-27 binding
    		•  0.39282199030202 bayes_pls_golite062009
  • interleukin-12 receptor binding
    		•  0.218984052557791 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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