Protein Overview: AHSP_MOUSE

General Information:
Name(s) found:	AHSP_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|83405067\|gb\|AAI10628.1\| Erythroid associated factor [Mus musculus] [NCBI NR] gi\|74144830\|dbj\|BAE27387.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|54114899\|dbj\|BAD60929.1\| alpha-hemoglobin stabilizing protein [Mus musculus] [NCBI NR] gi\|3089621\|gb\|AAC15075.1\| erythroid differentiation-related factor [Mus musculus] [NCBI NR] gi\|28628847\|gb\|AAO49383.1\|AF485327_1 erythroid associated factor [Mus musculus] [NCBI NR] gi\|26389777\|dbj\|BAC25789.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|23813664\|sp\|Q9CY02.1\|AHSP_MOUSE RecName: Full=Alpha-hemoglobin-stabilizing protein; AltName: Full=Erythroid-associated factor; AltName: Full=Erythroid differentiation-related factor [NCBI NR] gi\|18875418\|ref\|NP_573508.1\| erythroid associated factor [Mus musculus] [NCBI NR] gi\|13958317\|gb\|AAK50855.1\|AF364516_1 erythroid association factor [Mus musculus] [NCBI NR] gi\|12846978\|dbj\|BAB27388.1\| unnamed protein product [Mus musculus] [NCBI NR] Alpha-hemoglobin-stabilizing protein OS=Mus musculus GN=Ahsp PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None Alpha-hemoglobin stabilizing protein [hmr_yeast5_DM3-1_pombe.fasta] erythroid associated factor [HMR_022704-rand.fasta] Alpha-hemoglobin stabilizing protein [ipi.MOUSE.v3.06.fasta] erythroid associated factor [Mus musculus]gi\|13958317\|gb\|AAK50855.1\| erythroid association factor [Mus musculus]gi\|28628847\|gb\|AAO49383.1\| erythroid associated factor [Mus musculus]gi\|3089621\|gb\|AAC15075.1\| erythroid differentiation-related factor [Mus [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Alpha-hemoglobin-stabilizing protein [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_133245) erythroid associated factor [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10090 Alpha-hemoglobin stabilizing protein [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] erythroid associated factor [Mus musculus] [NCBI-RefSeq_mouse_na_03-19-2007_reversed.fasta] Alpha-hemoglobin-stabilizing protein (Erythroid-associated factor) (Erythroid differentiation-related factor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Erythroid associated factor [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] alpha-hemoglobin stabilizing protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] erythroid association factor [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] erythroid differentiation-related factor [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 ALPHA-HEMOGLOBIN STABILIZING PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Eraf Alpha-hemoglobin-stabilizing protein [mouse-ipi-250309-contam.fasta] alpha hemoglobin stabilizing protein [Mus musculus] [NCBI-RefSeq_mouse_na_10-19-2009_con_reversed.fasta] alpha-hemoglobin-stabilizing protein [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00110616.1\|SWISS-PROT:Q9CY02\|TREMBL:Q60F90\|REFSEQ:NP_573508 Tax_Id=10090 Gene_Symbol=Eraf Alpha-hemoglobin-stabilizing protein [ipi.MOUSE.fasta.20090209] Alpha-hemoglobin-stabilizing protein OS=Mus musculus GN=Ahsp [011711_HMR.fasta] Alpha-hemoglobin-stabilizing protein OS=Mus musculus GN=Ahsp PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] Tax_Id=10090 Gene_Symbol=Ahsp Alpha-hemoglobin-stabilizing protein [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|Q9CY02\|AHSP_MOUSE Alpha-hemoglobin-stabilizing protein OS=Mus musculus GN=Ahsp PE=2 SV=1 [uniprot.sptr.mouse.20130102] tr\|Q60F90\|Q60F90_MOUSE Alpha-hemoglobin stabilizing protein OS=Mus musculus GN=Ahsp PE=4 SV=1 [uniprot.sptr.mouse.20130102] Alpha-hemoglobin stabilizing protein OS=Mus musculus GN=Ahsp PE=4 SV=1 [mouse-uniprot-290313-contam.fasta] Alpha-hemoglobin stabilizing protein OS=Mus musculus GN=Ahsp PE=2 SV=1 [mouse-uniprot-oct2014-contam.fasta]
Organism:	Mus musculus
Length:	102 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	erythrocyte differentiation [IMP] hemopoiesis [IEA] protein folding [IDA] protein stabilization [IDA] hemoglobin metabolic process [IEA]
Molecular Function:	hemoglobin binding [IEA]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MAPFQSNKDL ISTGIKEFNV LLDQQVFDDP LISEEDMVIV VHDWVNLYTN YYKKLVHGEQ 60 61 EEQDRAMTEF QQELSTLGSQ FLAKYRTFLK SKEPPSNTLP SS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..102]	PSI-BLAST	51.221849	Crystal structure of AHSP bound to Fe(II) alpha-hemoglobin

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
hemoglobin binding	6.33731403252919	bayes_pls_golite062009
unfolded protein binding	4.17510328535304	bayes_pls_golite062009
binding	1.93645291666706	bayes_pls_golite062009
protein binding	0.449118977352733	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle