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Protein Overview: CDN2B_MOUSE

General Information:
Name(s) found: CDN2B_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|6671728|ref|NP_031696.1| cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus] [NCBI NR]
  • gi|3075497|gb|AAC14569.1| cyclin dependent kinase inhibitor 2B [Mus musculus] [NCBI NR]
  • gi|1762920|gb|AAB39833.1| p15INK4B [Mus musculus] [NCBI NR]
  • gi|1705728|sp|P55271.1|CDN2B_MOUSE RecName: Full=Cyclin-dependent kinase 4 inhibitor B; AltName: Full=p14-INK4b; AltName: Full=p15-INK4b [NCBI NR]
  • gi|149252693|ref|XP_001478592.1| PREDICTED: similar to Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) [Mus musculus] [NCBI NR]
  • gi|148699003|gb|EDL30950.1| cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus] [NCBI NR]
  • gi|12805107|gb|AAH02010.1| Cdkn2b protein [Mus musculus] [NCBI NR]
  • (P55271) Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) [Swiss-Prot]
  • Cyclin-dependent kinase 4 inhibitor B OS=Mus musculus GN=Cdkn2b PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):4-86888692 Cyclin-dependent kinase 4 inhibitor B [hmr_yeast5_DM3-1_pombe.fasta]
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [HMR_022704-rand.fasta]
  • Cyclin-dependent kinase 4 inhibitor B [ipi.MOUSE.v3.06.fasta]
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus]gi|12805107|gb|AAH02010.1| Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus]gi|1762920|gb|AAB39833.1| p15INK4B [Mus musculus]gi|3075497|gb|AAC14569.1| cyclin [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Cyclin-dependent kinase 4 inhibitor B [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_007670) cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • PREDICTED: similar to Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Cdkn2b protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • p15INK4B [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • cyclin dependent kinase inhibitor 2B [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 CYCLIN-DEPENDENT KINASE 4 INHIBITOR B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Cdkn2b;LOC100047564 Cyclin-dependent kinase 4 inhibitor B [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=LOC100047564;Cdkn2b Cyclin-dependent kinase 4 inhibitor B [ipi.MOUSE_jw_12may08.contam.fasta]
  • Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Mus musculus] [nr-271106-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Cdkn2b Cyclin-dependent kinase 4 inhibitor B [zeeyong.fasta]
  • Tax_Id=10090 Gene_Symbol=Cdkn2b;LOC100047564 Cyclin-dependent kinase 4 inhibitor B ENSMUSG00000073802 IPI00138143 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • cyclin-dependent kinase 4 inhibitor B [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00138143.1|SWISS-PROT:P55271|TREMBL:O54846;Q3UNM8;Q549R4;Q9QUJ3;Q9QUP0|ENSEMBL:ENSMUSP00000095595|REFSEQ:NP_031696;XP_001478592 Tax_Id=10090 Gene_Symbol=Cdkn2b;LOC100047564 Cyclin-dependent kinase 4 inhibitor B [ipi.MOUSE.fasta.20090209]
  • Cyclin-dependent kinase 4 inhibitor B OS=Mus musculus GN=Cdkn2b [011711_HMR.fasta]
  • sp|P55271|CDN2B_MOUSE Cyclin-dependent kinase 4 inhibitor B OS=Mus musculus GN=Cdkn2b PE=1 SV=1 [uniprot.sptr.mouse.20130102]
  • tr|Q549R4|Q549R4_MOUSE Cyclin dependent kinase inhibitor 2B OS=Mus musculus GN=Cdkn2b PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Cyclin dependent kinase inhibitor 2B OS=Mus musculus GN=Cdkn2b PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P55271, Cyclin dependent kinase inhibitor 2B OS=Mus musculus GN=Cdkn2b PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 130 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of cell proliferation [UNKNOWN]
    cell cycle [IEA]
    Molecular Function: kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGGSSDAGL ATAAARGQVE TVRQLLEAGA DPNALNRFGR RPIQVMMMGS AQVAELLLLH  60
   61 GAEPNCADPA TLTRPVHDAA REGFLDTLVV LHRAGARLDV CDAWGRLPVD LAEEQGHRDI 120
  121 ARYLHAATGD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] PSI-BLAST 22.30103 Tumor suppressor p15(ink4b)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.70

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle