Protein Overview: ICOSL_MOUSE

General Information:
Name(s) found:	ICOSL_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|7657220\|ref\|NP_056605.1\| icos ligand [Mus musculus] [NCBI NR] gi\|7288511\|gb\|AAF45149.1\| B7-related protein 1 [Mus musculus] [NCBI NR] gi\|6983942\|gb\|AAF34738.1\|AF199027_1 B7-like protein [Mus musculus] [NCBI NR] gi\|26334475\|dbj\|BAC30938.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|22137739\|gb\|AAH29227.1\| Icos ligand [Mus musculus] [NCBI NR] gi\|15214053\|sp\|Q9JHJ8.1\|ICOSL_MOUSE RecName: Full=ICOS ligand; AltName: Full=B7 homolog 2; Short=B7-H2; AltName: Full=B7-like protein Gl50; AltName: Full=B7-related protein 1; Short=B7RP-1; AltName: Full=LICOS; AltName: CD_antigen=CD275; Flags: Precursor [NCBI NR] gi\|148699800\|gb\|EDL31747.1\| icos ligand [Mus musculus] [NCBI NR] ICOS ligand OS=Mus musculus GN=Icoslg PE=1 SV=1 [Swiss-Prot] (Q9JHJ8) ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein-1) (B7RP-1) (LICOS) [Swiss-Prot] Ensembl_locations(Chr-bp):10-77880183 Splice isoform 1 of Q9JHJ8 ICOS ligand precursor [hmr_yeast5_DM3-1_pombe.fasta] icos ligand; EST BG071784 [HMR_022704-rand.fasta] Splice Isoform 1 of ICOS ligand precursor [ipi.MOUSE.v3.06.fasta] B7-related protein 1 [Mus musculus]gi\|7657220\|ref\|NP_056605.1\| icos ligand [Mus musculus]gi\|22137739\|gb\|AAH29227.1\| Icos ligand [Mus musculus]gi\|6983942\|gb\|AAF34738.1\| B7-like protein [Mus musculus]gi\|15214053\|sp\|Q9JHJ8\|ICOL_MOUSE ICOS ligand precurso [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 1 of ICOS ligand precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_015790) icos ligand [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] icos ligand [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Icos ligand [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] B7-related protein 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] B7-like protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Icosl Isoform 1 of ICOS ligand [mouse-ipi-250309-contam.fasta] icos ligand precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Icosl Isoform 1 of ICOS ligand precursor [ipi.MOUSE_jw_12may08.contam.fasta] ICOS ligand precursor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00314681.5\|SWISS-PROT:Q9JHJ8-1\|TREMBL:Q3UWV7;Q544C7;Q571G9\|ENSEMBL:ENSMUSP00000101032\|REFSEQ:NP_056605 Tax_Id=10090 Gene_Symbol=Icosl Isoform 1 of ICOS ligand [ipi.MOUSE.fasta.20090209] Isoform 1 of ICOS ligand OS=Mus musculus GN=Icoslg [011711_HMR.fasta] sp\|Q9JHJ8\|ICOSL_MOUSE ICOS ligand OS=Mus musculus GN=Icoslg PE=1 SV=1 [uniprot.sptr.mouse.20130102] tr\|Q544C7\|Q544C7_MOUSE Icos ligand OS=Mus musculus GN=Icosl PE=2 SV=1 [uniprot.sptr.mouse.20130102] Icos ligand OS=Mus musculus GN=Icosl PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
Organism:	Mus musculus
Length:	322 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IDA] membrane [IEA] integral to membrane [NAS] external side of plasma membrane [IDA]
Biological Process:	signal transduction [NAS] T cell activation [NAS] B cell activation [IEA] positive regulation of activated T cell proliferation [TAS] positive regulation of interleukin-4 biosynthetic process [IMP] isotype switching [NAS]
Molecular Function:	protein binding [IPI] receptor binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLKCPCFVS LGTRQPVWKK LHVSSGFFSG LGLFLLLLSS LCAASAETEV GAMVGSNVVL  60
   61 SCIDPHRRHF NLSGLYVYWQ IENPEVSVTY YLPYKSPGIN VDSSYKNRGH LSLDSMKQGN 120
  121 FSLYLKNVTP QDTQEFTCRV FMNTATELVK ILEEVVRLRV AANFSTPVIS TSDSSNPGQE 180
  181 RTYTCMSKNG YPEPNLYWIN TTDNSLIDTA LQNNTVYLNK LGLYDVISTL RLPWTSRGDV 240
  241 LCCVENVALH QNITSISQAE SFTGNNTKNP QETHNNELKV LVPVLAVLAA AAFVSFIIYR 300
  301 RTRPHRSYTG PKTVQLELTD HA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ICOSL_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: