Protein Overview: SLT2_MOUSE, SLIT...

General Information:
Name(s) found:	SLT2_MOUSE [Swiss-Prot] SLIT2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5532495\|gb\|AAD44759.1\|AF144628_1 SLIT2 [Mus musculus] [NCBI NR] gi\|45477343\|sp\|Q9R1B9.1\|SLIT2_MOUSE RecName: Full=Slit homolog 2 protein; Short=Slit-2; Contains: RecName: Full=Slit homolog 2 protein N-product; Contains: RecName: Full=Slit homolog 2 protein C-product; Flags: Precursor [NCBI NR] gi\|30794374\|ref\|NP_848919.2\| slit homolog 2 [Mus musculus] [NCBI NR] (Q9R1B9) Slit homolog 2 protein precursor (Slit-2) [Swiss-Prot] Slit homolog 2 protein OS=Mus musculus GN=Slit2 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):5-46894189;5-46894189;5-46894189;5-46894189 SLIT2 [hmr_yeast5_DM3-1_pombe.fasta] slit homolog 2; neurogenic extracellular slit protein; downregulated during adipocyte differentiation-1 [HMR_022704-rand.fasta] slit homolog 2 [Mus musculus]gi\|45477343\|sp\|Q9R1B9\|SLT2_MOUSE Slit homolog 2 protein precursor (Slit-2)gi\|5532495\|gb\|AAD44759.1\| SLIT2 [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Slit homolog 2 protein precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] slit homolog 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SLIT2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SLIT HOMOLOG 2 PROTEIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Slit2 Slit homolog 2 protein [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Slit2 Slit homolog 2 protein precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Slit2 Slit homolog 2 protein precursor ENSMUSG00000031558 IPI00128415 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00128415.3\|SWISS-PROT:Q9R1B9\|TREMBL:B2RX05;Q5DTL5;Q8BPJ0\|ENSEMBL:ENSMUSP00000033967\|REFSEQ:NP_848919 Tax_Id=10090 Gene_Symbol=Slit2 Slit homolog 2 protein [ipi.MOUSE.fasta.20090209] Slit homolog 2 protein OS=Mus musculus GN=Slit2 [011711_HMR.fasta]
Organism:	Mus musculus
Length:	1521 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IDA] extracellular region [IEA] plasma membrane [UNKNOWN]
Biological Process:	cell-cell adhesion [IGI][IMP] negative chemotaxis [IMP] retinal ganglion cell axon guidance [IGI][IMP] multicellular organismal development [IEA] negative regulation of cell proliferation [IGI] negative regulation of inflammatory response [UNKNOWN] nervous system development [IEA] neuron projection morphogenesis [IGI][IMP] mammary gland duct morphogenesis [IGI][IMP] telencephalon cell migration [IGI] axon guidance [IDA][IGI][IMP] mammary duct terminal end bud growth [IMP] olfactory bulb development [IGI] negative regulation of gene expression [IGI] chemotaxis [IEA] metanephros development [IMP] in utero embryonic development [IMP] axonogenesis [IDA][IMP] cell differentiation [IEA] dorsal/ventral axon guidance [IGI][IMP]
Molecular Function:	protein binding [IEA] calcium ion binding [IEA] heparan sulfate proteoglycan binding [UNKNOWN] chemorepellent activity [IMP] receptor binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIGWQTLS LSLGLVLSIL NKVAPQACPA QCSCSGSTVD CHGLALRSVP RNIPRNTERL  60
   61 DLNGNNITRI TKTDFAGLRH LRVLQLMENR ISTIERGAFQ DLKELERLRL NRNNLQLFPE 120
  121 LLFLGTAKLY RLDLSENQIQ AIPRKAFRGA VDIKNLQLDY NQISCIEDGA FRALRDLEVL 180
  181 TLNNNNITRL SVASFNHMPK LRTFRLHSNN LYCDCHLAWL SDWLRQRPRV GLYTQCMGPS 240
  241 HLRGHNVAEV QKREFVCSGH QSFMAPSCSV LHCPAACTCS NNIVDCRGKG LTEIPTNLPE 300
  301 TITEIRLEQN SIRVIPPGAF SPYKKLRRLD LSNNQISELA PDAFQGLRSL NSLVLYGNKI 360
  361 TELPKSLFEG LFSLQLLLLN ANKINCLRVD AFQDLHNLNL LSLYDNKLQT VAKGTFSALR 420
  421 AIQTMHLAQN PFICDCHLKW LADYLHTNPI ETSGARCTSP RRLANKRIGQ IKSKKFRCSG 480
  481 TEDYRSKLSG DCFADLACPE KCRCEGTTVD CSNQRLNKIP DHIPQYTAEL RLNNNEFTVL 540
  541 EATGIFKKLP QLRKINFSNN KITDIEEGAF EGASGVNEIL LTSNRLENVQ HKMFKGLESL 600
  601 KTLMLRSNRI SCVGNDSFIG LGSVRLLSLY DNQITTVAPG AFDSLHSLST LNLLANPFNC 660
  661 NCHLAWLGEW LRRKRIVTGN PRCQKPYFLK EIPIQDVAIQ DFTCDDGNDD NSCSPLSRCP 720
  721 SECTCLDTVV RCSNKGLKVL PKGIPKDVTE LYLDGNQFTL VPKELSNYKH LTLIDLSNNR 780
  781 ISTLSNQSFS NMTQLLTLIL SYNRLRCIPP RTFDGLKSLR LLSLHGNDIS VVPEGAFNDL 840
  841 SALSHLAIGA NPLYCDCNMQ WLSDWVKSEY KEPGIARCAG PGEMADKLLL TTPSKKFTCQ 900
  901 GPVDITIQAK CNPCLSNPCK NDGTCNNDPV DFYRCTCPYG FKGQDCDVPI HACISNPCKH 960
  961 GGTCHLKEGE NAGFWCTCAD GFEGENCEVN IDDCEDNDCE NNSTCVDGIN NYTCLCPPEY1020
 1021 TGELCEEKLD FCAQDLNPCQ HDSKCILTPK GFKCDCTPGY IGEHCDIDFD DCQDNKCKNG1080
 1081 AHCTDAVNGY TCVCPEGYSG LFCEFSPPMV LPRTSPCDNF DCQNGAQCII RINEPICQCL1140
 1141 PGYLGEKCEK LVSVNFVNKE SYLQIPSAKV RPQTNITLQI ATDEDSGILL YKGDKDHIAV1200
 1201 ELYRGRVRAS YDTGSHPASA IYSVETINDG NFHIVELLTL DSSLSLSVDG GSPKVITNLS1260
 1261 KQSTLNFDSP LYVGGMPGKN NVASLRQAPG QNGTSFHGCI RNLYINSELQ DFRKMPMQTG1320
 1321 ILPGCEPCHK KVCAHGMCQP SSQSGFTCEC EEGWMGPLCD QRTNDPCLGN KCVHGTCLPI1380
 1381 NAFSYSCKCL EGHGGVLCDE EEDLFNPCQM IKCKHGKCRL SGVGQPYCEC NSGFTGDSCD1440
 1441 REISCRGERI RDYYQKQQGY AACQTTKKVS RLECRGGCAG GQCCGPLRSK RRKYSFECTD1500
 1501 GSSFVDEVEK VVKCGCARCA S

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SLT2_MOUSE, SLIT...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: