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Protein Overview: TEP1_MOUSE

General Information:
Name(s) found: TEP1_MOUSE [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Telomerase protein component 1 OS=Mus musculus GN=Tep1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 2629 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    chromosome, telomeric region [IEA]
    soluble fraction [IDA]
    ribonucleoprotein complex [UNKNOWN]
    cytoplasm [UNKNOWN]
    nuclear matrix [UNKNOWN]
    chromosome [IEA]
    Biological Process: [NOT]telomere maintenance via telomerase [IGI]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    RNA binding [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKLCGHVPG HSDILSLKNR CLTMLPDLQP LEKIHGHRSV HSDILSLENQ CLTMLSDLQP  60
   61 TERIDGHISV HPDILSLENR CLTMLPDLQP LEKLCGHMSS HPDVLSLENQ CLATLPTVKS 120
  121 TALTSPLLQG LHISHTAQAD LHSLKTSNCL LPELPTKKTP CFSEELDLPP GPRALKSMSA 180
  181 TAQVQEVALG QWCVSKEKEF QEEESTEVPM PLYSLSLEEE EVEAPVLKLT SGDSGFHPET 240
  241 TDQVLQEKKM ALLTLLCSAL ASNVNVKDAS DLTRASILEV CSALASLEPE FILKASLYAR 300
  301 QQLNLRDIAN TVLAVAALLP ACRPHVRRYY SAIVHLPSDW IQVAEFYQSL AEGDEKKLVS 360
  361 LPACLRAAMT DKFAEFDEYQ LAKYNPRKHR SKRRSRQPPR PQKTERPFSE RGKCFPKSLW 420
  421 PLKNEQITFE AAYNAMPEKN RLPRFTLKKL VEYLHIHKPA QHVQALLGYR YPATLELFSR 480
  481 SHLPGPWESS RAGQRMKLRR PETWERELSL RGNKASVWEE LIDNGKLPFM AMLRNLCNLL 540
  541 RTGISARHHE LVLQRLQHEK SVVHSRQFPF RFLNAHDSID KLEAQLRSKA SPFPSNTTLM 600
  601 KRIMIRNSKK NRRPASRKHL CTLTRRQLRA AMTIPVMYEQ LKREKLRLHK ARQWNCDVEL 660
  661 LERYRQALET AVNLSVKHNL SPMPGRTLLV YLTDANADRL CPKSHSQGPP LNYVLLLIGM 720
  721 MVARAEQVTV CLCGGGFVKT PVLTADEGIL KTAIKLQAQV QELEGNDEWP LDTFGKYLLS 780
  781 LAVQRTPIDR VILFGQRMDT ELLKVAKQII WQHVNSKCLF VGVLLQKTQY ISPNLNPNDV 840
  841 TLSGCTDGIL KFIAEHGASR LLEHVGQLDK LFKIPPPPGK TQAPSLRPLE ENIPGPLGPI 900
  901 SQHGWRNIRL FISSTFRDMH GERDLLMRSV LPALQARVFP HRISLHAIDL RWGITEEETR 960
  961 RNRQLEVCLG EVENSQLFVG ILGSRYGYIP PSYDLPDHPH FHWTHEYPSG RSVTEMEVMQ1020
 1021 FLNRGQRSQP SAQALIYFRD PDFLSSVPDA WKPDFISESE EAAHRVSELK RYLHEQKEVT1080
 1081 CRSYSCEWGG VAAGRPYTGG LEEFGQLVLQ DVWSMIQKQH LQPGAQLEQP TSISEDDLIQ1140
 1141 TSFQQLKTPT SPARPRLLQD TVQQLLLPHG RLSLVTGQAG QGKTAFLASL VSALKVPDQP1200
 1201 NEPPFVFFHF AAARPDQCLA LNLLRRLCTH LRQKLGELSA LPSTYRGLVW ELQQKLLLKF1260
 1261 AQSLQPAQTL VLIIDGADKL VDRNGQLISD WIPKSLPRRV HLVLSVSSDS GLGETLQQSQ1320
 1321 GAYVVALGSL VPSSRAQLVR EELALYGKRL EESPFNNQMR LLLAKQGSSL PLYLHLVTDY1380
 1381 LRLFTLYEQV SERLRTLPAT LPLLLQHILS TLEQEHGHDV LPQALTALEV TRSGLTVDQL1440
 1441 HAILSTWLIL PKETKSWEEV LAASHSGNPF PLCPFAYLVQ SLRSLLGEGP VERPGARLCL1500
 1501 SDGPLRTTIK RRYGKRLGLE KTAHVLIAAH LWKTCDPDAS GTFRSCPPEA LKDLPYHLLQ1560
 1561 SGNHGLLAEF LTNLHVVAAY LEVGLVPDLL EAHVLYASSK PEANQKLPAA DVAVFHTFLR1620
 1621 QQASLLTQYP LLLLQQAASQ PEESPVCCQA PLLTQRWHDQ FTLKWINKPQ TLKGQQSLSL1680
 1681 TMSSSPTAVA FSPNGQRAAV GTASGTIYLL NLKTWQEEKA VVSGCDGISS FAFLSDTALF1740
 1741 LTTFDGHLEL WDLQHGCWVF QTKAHQYQIT GCCLSPDRRL LATVCLGGYL KLWDTVRGQL1800
 1801 AFQYTHPKSL NCVAFHPEGQ VVATGSWAGS ITFFQADGLK VTKELGAPGP SVCSLAFNKP1860
 1861 GKIVAVGRID GTVELWAWQE GARLAAFPAQ CGCVSAVLFL HAGDRFLTAG EDGKAQLWSG1920
 1921 FLGRPRGCLG SLPLSPALSV ALNPDGDQVA VGYREDGINI YKISSGSQGP QHQELNVAVS1980
 1981 ALVWLSPSVL VSGAEDGSLH GWMFKGDSLH SLWLLSRYQK PVLGLAASRE LMAAASEDFT2040
 2041 VRLWPRQLLT QPHVHAVELP CCAELRGHEG PVCCCSFSPD GGILATAGRD RNLLCWDMKI2100
 2101 AQAPLLIHTF SSCHRDWITG CAWTKDNILV SCSSDGSVGL WNPEAGQQLG QFSGHQSAVS2160
 2161 AVVAVEEHIV SVSRDGTLKV WDHQGVELTS IPAHSGPISQ CAAALEPRPG GQPGSELLVV2220
 2221 TVGLDGATKL WHPLLVCQIR TLQGHSGPVT AAAASEASGL LLTSDDSSVQ LWQIPKEADD2280
 2281 SYKPRSSVAI TAVAWAPDGS MVVSGNEAGE LTLWQQAKAV ATAQAPGRVS HLIWYSANSF2340
 2341 FVLSANENVS EWQVGLRKGS TSTSSSLHLK RVLQEDWGVL TGLGLAPDGQ SLILMKEDVE2400
 2401 LLEMKPGSIP SSICRRYGVH SSILCTSKEY GLFYLQQGDS GLLSILEQKE SGEFEEILDF2460
 2461 NLNLNNPNGS PVSITQAKPE SESSLLCATS DGMLWNLSEC TSEGEWIVDN IWQKKAKKPK2520
 2521 TQTLETELSP HSELDFSIDC WIDPTNLKAQ QCKKIHLGSV TALHVLPGLL VTASKDRDVK2580
 2581 LWERPSMQLL GLFRCEGPVS CLEPWMEPSS PLQLAVGDTQ GNLYFLSWE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle