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Protein Overview: NRTN_MOUSE

General Information:
Name(s) found: NRTN_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|6679136|ref|NP_032764.1| neurturin [Mus musculus] [NCBI NR]
  • gi|34784402|gb|AAH57993.1| Neurturin [Mus musculus] [NCBI NR]
  • gi|2501181|sp|P97463.1|NRTN_MOUSE RecName: Full=Neurturin; Flags: Precursor [NCBI NR]
  • gi|1731679|gb|AAC52954.1| prepro-neurturin [Mus musculus] [NCBI NR]
  • gi|148706253|gb|EDL38200.1| neurturin [Mus musculus] [NCBI NR]
  • Neurturin OS=Mus musculus GN=Nrtn PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):17-55129107 Neurturin precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • neurturin [HMR_022704-rand.fasta]
  • Neurturin precursor [ipi.MOUSE.v3.06.fasta]
  • neurturin [Mus musculus]gi|34784402|gb|AAH57993.1| Neurturin [Mus musculus]gi|2501181|sp|P97463|NRTN_MOUSE Neurturin precursorgi|1731679|gb|AAC52954.1| prepro-neurturin [Mus musculus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Neurturin precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_008738) neurturin [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • neurturin [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Neurturin [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • prepro-neurturin [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 NEURTURIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Nrtn Neurturin [mouse-ipi-250309-contam.fasta]
  • neurturin precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Nrtn Neurturin precursor [ipi.MOUSE_jw_12may08.contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Nrtn Neurturin precursor ENSMUSG00000039481 IPI00125527 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • IPI:IPI00125527.1|SWISS-PROT:P97463|ENSEMBL:ENSMUSP00000046512|REFSEQ:NP_032764 Tax_Id=10090 Gene_Symbol=Nrtn Neurturin [ipi.MOUSE.fasta.20090209]
  • Neurturin OS=Mus musculus GN=Nrtn [011711_HMR.fasta]
  • sp|P97463|NRTN_MOUSE Neurturin OS=Mus musculus GN=Nrtn PE=1 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 195 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    axon [UNKNOWN]
    Biological Process: neural crest cell migration [UNKNOWN]
    neuron projection development [UNKNOWN]
    transmembrane receptor protein tyrosine kinase signaling pathway [IGI]
    nerve development [IMP]
    Molecular Function: growth factor activity [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRWKAAALV SLICSSLLSV WMCQEGLLLG HRLGPALAPL RRPPRTLDAR IARLAQYRAL  60
   61 LQGAPDAVEL RELSPWAARI PGPRRRAGPR RRRARPGARP CGLRELEVRV SELGLGYTSD 120
  121 ETVLFRYCAG ACEAAIRIYD LGLRRLRQRR RVRRERARAH PCCRPTAYED EVSFLDVHSR 180
  181 YHTLQELSAR ECACV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 40.221849 Glial cell-derived neurotrophic factor, GDNF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor serine/threonine kinase binding
    		•  4.27815942287831 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  4.14014703177357 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  4.14014703177357 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
    		•  3.8943658126028 bayes_pls_golite062009
  • receptor binding
    		•  2.8479912121811 bayes_pls_golite062009
  • binding
    		•  2.64101807129423 bayes_pls_golite062009
  • protein binding
    		•  2.36794464190805 bayes_pls_golite062009
  • growth factor activity
    		•  1.8892192272657 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  0.801389802382386 bayes_pls_golite062009
  • growth factor binding
    		•  0.772327486125282 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.721924896985173 bayes_pls_golite062009
  • signal transducer activity
    		•  0.721924896985173 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.697058311884552 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.344090347736442 bayes_pls_golite062009
  • cell surface binding
    		•  0.296497146463694 bayes_pls_golite062009
  • cytokine activity
    		•  0.284134661359739 bayes_pls_golite062009
  • identical protein binding
    		•  0.273591586673912 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle