Protein Overview: NRTN_MOUSE

General Information:
Name(s) found:	NRTN_MOUSE [Swiss-Prot]
Description(s) found: Found 23 descriptions. SHOW ALL	Neurturin OS=Mus musculus GN=Nrtn PE=1 SV=1 [Swiss-Prot]
Organism:	Mus musculus
Length:	195 amino acids
Gene Ontology:
Cellular Component:	extracellular region [IEA] axon [UNKNOWN]
Biological Process:	neural crest cell migration [UNKNOWN] neuron projection development [UNKNOWN] transmembrane receptor protein tyrosine kinase signaling pathway [IGI] nerve development [IMP]
Molecular Function:	growth factor activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRWKAAALV SLICSSLLSV WMCQEGLLLG HRLGPALAPL RRPPRTLDAR IARLAQYRAL  60
   61 LQGAPDAVEL RELSPWAARI PGPRRRAGPR RRRARPGARP CGLRELEVRV SELGLGYTSD 120
  121 ETVLFRYCAG ACEAAIRIYD LGLRRLRQRR RVRRERARAH PCCRPTAYED EVSFLDVHSR 180
  181 YHTLQELSAR ECACV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..195]	PSI-BLAST	40.221849	Glial cell-derived neurotrophic factor, GDNF

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
receptor serine/threonine kinase binding	4.27815942287831	bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding	4.14014703177357	bayes_pls_golite062009
transforming growth factor beta receptor binding	4.14014703177357	bayes_pls_golite062009
type II transforming growth factor beta receptor binding	3.8943658126028	bayes_pls_golite062009
receptor binding	2.8479912121811	bayes_pls_golite062009
binding	2.64101807129423	bayes_pls_golite062009
protein binding	2.36794464190805	bayes_pls_golite062009
growth factor activity	1.8892192272657	bayes_pls_golite062009
vascular endothelial growth factor receptor binding	0.801389802382386	bayes_pls_golite062009
growth factor binding	0.772327486125282	bayes_pls_golite062009
molecular transducer activity	0.721924896985173	bayes_pls_golite062009
signal transducer activity	0.721924896985173	bayes_pls_golite062009
protein dimerization activity	0.697058311884552	bayes_pls_golite062009
protein homodimerization activity	0.344090347736442	bayes_pls_golite062009
cell surface binding	0.296497146463694	bayes_pls_golite062009
cytokine activity	0.284134661359739	bayes_pls_golite062009
identical protein binding	0.273591586673912	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle