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Protein Overview: PLGF_MOUSE

General Information:
Name(s) found: PLGF_MOUSE [Swiss-Prot]
Description(s) found:
Found 26 descriptions.
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  • Placenta growth factor OS=Mus musculus GN=Pgf PE=2 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 158 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN]
    membrane [IEA]
    extracellular region [UNKNOWN]
    Biological Process: positive regulation of cell division [IEA]
    angiogenesis [IEA]
    multicellular organismal development [IEA]
    branching involved in ureteric bud morphogenesis [IDA]
    cell differentiation [IEA]
    positive regulation of endothelial cell proliferation [UNKNOWN]
    regulation of morphogenesis of a branching structure [IDA]
    Molecular Function: growth factor activity [IEA]
    protein homodimerization activity [UNKNOWN]
    protein binding [IPI]
    protein heterodimerization activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVMKLFTCF LQVLAGLAVH SQGALSAGNN STEVEVVPFN EVWGRSYCRP MEKLVYILDE  60
   61 YPDEVSHIFS PSCVLLSRCS GCCGDEGLHC VPIKTANITM QILKIPPNRD PHFYVEMTFS 120
  121 QDVLCECRPI LETTKAERRK TKGKRKRSRN SQTEEPHP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 36.69897 Placenta growth factor-1, PLGF-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cell surface binding
    		•  5.03803877600605 bayes_pls_golite062009
  • growth factor activity
    		•  4.74498867224238 bayes_pls_golite062009
  • receptor binding
    		•  4.70889547404918 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 1 binding
    		•  4.5759745938637 bayes_pls_golite062009
  • cytokine activity
    		•  3.82319060838266 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  3.68487867644309 bayes_pls_golite062009
  • protein binding
    		•  3.16282476674164 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  3.12262133458315 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 2 binding
    		•  2.88765567751765 bayes_pls_golite062009
  • heparin binding
    		•  2.81661725670177 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  2.47418832835206 bayes_pls_golite062009
  • fibronectin binding
    		•  2.46921434924493 bayes_pls_golite062009
  • glial cell line-derived neurotrophic factor receptor binding
    		•  2.42595321135263 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.42568523771453 bayes_pls_golite062009
  • binding
    		•  2.37954321554411 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  2.27945700811005 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  2.27945700811005 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
    		•  2.12427087117957 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
    		•  2.01478614969692 bayes_pls_golite062009
  • growth factor binding
    		•  1.84040204020368 bayes_pls_golite062009
  • protein dimerization activity
    		•  1.44846386076063 bayes_pls_golite062009
  • hormone activity
    		•  1.39628583804208 bayes_pls_golite062009
  • protein homodimerization activity
    		•  1.13743310822539 bayes_pls_golite062009
  • platelet-derived growth factor binding
    		•  1.08152379636602 bayes_pls_golite062009
  • identical protein binding
    		•  1.0030262164995 bayes_pls_golite062009
  • pattern binding
    		•  0.90497366619649 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 3 binding
    		•  0.583797120004309 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.408562885230686 bayes_pls_golite062009
  • morphogen activity
    		•  0.30873436240916 bayes_pls_golite062009
  • neurotrophin receptor binding
    		•  0.12862133971438 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.0235054088545197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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