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View Structure Prediction Details

Protein: PLGF_MOUSE
Organism: Mus musculus
Length: 158 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLGF_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109071303 - gi|109071303|ref|XP_001089925.1| PREDICTED: similar to vascular endothelial growth factor isoform d ...
212.0 [0..19] [156..498]
gi|76781484 - gi|76781484|ref|NP_001020540.2| vascular endothelial growth factor A isoform e precursor [Homo sapie...
206.0 [0..19] [156..202]
PLGF_RAT - Placenta growth factor OS=Rattus norvegicus GN=Pgf PE=1 SV=1
205.0 [0..1] [157..1]
gi|26224930|gb|A... - vascular endothelial growth factor A [Mustela vison]
gi|26224930 - gi|26224930|gb|AAN76365.1| vascular endothelial growth factor A [Mustela vison]
198.0 [0..19] [156..22]
VEGFA_PIG - Vascular endothelial growth factor A OS=Sus scrofa GN=VEGFA PE=2 SV=1
gi|1093962, gi|1... - gi|1093962|prf||2105202A vascular endothelial growth factor, pir||S52130 vascular endothelial growth...
198.0 [0..19] [156..22]
gi|160358813, gi... - gi|4768927|gb|AAD29682.1|AF133248_1 vascular endothelial growth factor 164 [Canis familiaris], gi|16...
197.0 [0..19] [156..22]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVMKLFTCF LQVLAGLAVH SQGALSAGNN STEVEVVPFN EVWGRSYCRP MEKLVYILDE  60
   61 YPDEVSHIFS PSCVLLSRCS GCCGDEGLHC VPIKTANITM QILKIPPNRD PHFYVEMTFS 120
  121 QDVLCECRPI LETTKAERRK TKGKRKRSRN SQTEEPHP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.69897
Match: 1fzvA
Description: Placenta growth factor-1, PLGF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cell surface binding 5.03803877600605 bayes_pls_golite062009
growth factor activity 4.74498867224238 bayes_pls_golite062009
receptor binding 4.70889547404918 bayes_pls_golite062009
vascular endothelial growth factor receptor 1 binding 4.5759745938637 bayes_pls_golite062009
cytokine activity 3.82319060838266 bayes_pls_golite062009
vascular endothelial growth factor receptor binding 3.68487867644309 bayes_pls_golite062009
protein binding 3.16282476674164 bayes_pls_golite062009
glycosaminoglycan binding 3.12262133458315 bayes_pls_golite062009
vascular endothelial growth factor receptor 2 binding 2.88765567751765 bayes_pls_golite062009
heparin binding 2.81661725670177 bayes_pls_golite062009
platelet-derived growth factor receptor binding 2.47418832835206 bayes_pls_golite062009
fibronectin binding 2.46921434924493 bayes_pls_golite062009
glial cell line-derived neurotrophic factor receptor binding 2.42595321135263 bayes_pls_golite062009
polysaccharide binding 2.42568523771453 bayes_pls_golite062009
binding 2.37954321554411 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 2.27945700811005 bayes_pls_golite062009
transforming growth factor beta receptor binding 2.27945700811005 bayes_pls_golite062009
type II transforming growth factor beta receptor binding 2.12427087117957 bayes_pls_golite062009
receptor serine/threonine kinase binding 2.01478614969692 bayes_pls_golite062009
growth factor binding 1.84040204020368 bayes_pls_golite062009
protein dimerization activity 1.44846386076063 bayes_pls_golite062009
hormone activity 1.39628583804208 bayes_pls_golite062009
protein homodimerization activity 1.13743310822539 bayes_pls_golite062009
platelet-derived growth factor binding 1.08152379636602 bayes_pls_golite062009
identical protein binding 1.0030262164995 bayes_pls_golite062009
pattern binding 0.90497366619649 bayes_pls_golite062009
vascular endothelial growth factor receptor 3 binding 0.583797120004309 bayes_pls_golite062009
protein heterodimerization activity 0.408562885230686 bayes_pls_golite062009
morphogen activity 0.30873436240916 bayes_pls_golite062009
neurotrophin receptor binding 0.12862133971438 bayes_pls_golite062009
carbohydrate binding 0.0235054088545197 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle