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Protein Overview: FBpp0300846

General Information:
Name(s) found: FBpp0300846 [FlyBase]
Description(s) found:
Found 17 descriptions.
SHOW ALL
  • type=protein; loc=3R:join(22363345..22363506,22370765..22370882,22380079..22380661,22380955..22381373,22392083..22392297,22392646..22392948,22393010..22393089,22393199..22393467,22399226..22399492,22399576..22400183,22400302..22400502,22400573..22400759,22400887..22401170,22402079..22402363,22404446..22404553,22404824..22405003,22405366..22405524,22405611..22405824,22405900..22405988,22406055..22406348,22406418..22406744,22415630..22415780,22416163..22416439,22420498..22420537); ID=FBpp0300846; name=scrib-PH; parent=FBgn0263289,FBtr0308622; dbxref=FlyBase_Annotation_IDs:CG43398-PH,FlyBase:FBpp0300846,REFSEQ:NP_001014670,GB_protein:AAX52995; MD5=fe2361f8dca85e6dce0ac8051c515210; length=1939; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1939 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKCIPIFKG CNRQVEFVDK RHCSLPQVPE EILRYSRTLE ELFLDANHIR DLPKNFFRLH  60
   61 RLRKLGLSDN EIGRLPPDIQ NFENLVELDV SRNDIPDIPD DIKHLQSLQV ADFSSNPIPK 120
  121 LPSGFSQLKN LTVLGLNDMS LTTLPADFGS LTQLESLELR ENLLKHLPET ISQLTKLKRL 180
  181 DLGDNEIEDL PPYLGYLPGL HELWLDHNQL QRLPPELGLL TKLTYLDVSE NRLEELPNEI 240
  241 SGLVSLTDLD LAQNLLEALP DGIAKLSRLT ILKLDQNRLQ RLNDTLGNCE NMQELILTEN 300
  301 FLSELPASIG QMTKLNNLNV DRNALEYLPL EIGQCANLGV LSLRDNKLKK LPPELGNCTV 360
  361 LHVLDVSGNQ LLYLPYSLVN LQLKAVWLSE NQSQPLLTFQ PDTDAETGEQ VLSCYLLPQQ 420
  421 EYQPITPARD LESDSEPFEE REPSRTVVKF SEEATQEKET PFVRQNTPHP KDLKAKAQKL 480
  481 KVERSRNEEH ANLVTLPEEN GTKLAETPTE TRTIANNHQQ QPHPVQQPIV GVNSKQPVVV 540
  541 GVVTPTTTTV APTGVQGGSE GASSTANNVK AATAAVVAEL AATVGGSDEV QDDDEQEDEF 600
  601 ESDRRVGFQV EGEDDDFYKR PPKLHRRDTP HHLKNKRVQH LTDKQASEIL ANALASQERN 660
  661 DTTPQHSLSG KVTSPIEEEE QLEVEQEQQQ QQQQHPFDSS LSPISAGKTA EASTDPANQA 720
  721 MFNVKIKVKE GNNTLPRNGQ RSNGNFSYSG AGSGRNSPAM SSLRSSLASS NRSPSGSLQR 780
  781 KGKRVRIVTS YDPIDRDYER QRQHYDNLDG VTELRLEQYE IHIERTAAGL GLSIAGGKGS 840
  841 TPFKGDDDGI FISRVTEAGP ADLAGLKVGD KVIKVNGIVV VDADHYQAVQ VLKACGAVLV 900
  901 LVVQREVTRL IGHPVFSEDG SVSQISVETR PLVADAPPAA SISHERYIPA PIEIVPQQQH 960
  961 LQQQQQQPIQ QVAPTHSYSG NVFATPTAAQ TVQPAVSAAP NGLLLNGREA PLSYIQLHTT1020
 1021 LIRDQIGQGL GFSIAGGKGS PPFKDDCDGI FISRITEGGL AYRDGKIMVG DRVMAINGND1080
 1081 MTEAHHDAAV ACLTEPQRFV RLVLQREYRG PLEPPTSPRS PAVLNSLSPS GYLANRPANF1140
 1141 SRSVVEVEQP YKYNTLATTT PTPKPTVPAS ISNNNNTLPS SKTNGFATAA AATIDSSTGQ1200
 1201 PVPAPRRTNS VPMGDGDIGA GSTTSGDSGE AQPSSLRPLT SDDFQAMIPA HFLSGGSQHQ1260
 1261 VHVARPNEVG VSAVTVNVNK PQPDLPMFPA APTELGRVTE TITKSTFTET VMTRITDNQL1320
 1321 AEPLISEVVL PKNQGSLGFS IIGGTDHSCV PFGTREPGIF ISHIVPGGIA SKCGKLRMGD1380
 1381 RILKVNEADV SKATHQDAVL ELLKPGDEIK LTIQHDPLPP GFQEVLLSKA EGERLGMHIK1440
 1441 GGLNGQRGNP ADPSDEGVFV SKINSVGAAR RDGRLKVGMR LLEVNGHSLL GASHQDAVNV1500
 1501 LRNAGNEIQL VVCKGYDKSN LIHSIGQAGG MSTGFNSSAS CSGGSRQGSR ASETGSELSQ1560
 1561 SQSVSSLDHE EDERLRQDFD VFASQKPDAQ QPTGPSVLAA AAAMVHGASS PTPPAATSNI1620
 1621 TPLPTAAAVA SADLTAPDTP ATQTVALIHA EQQAHQQQQQ TQLAPLGQEK STQEKVLEIV1680
 1681 RAADAFTTVP PKSPSEHHEQ DKIQKTTTVV ISKHTLDTNP TTPTTPAAPL SIAGAESANS1740
 1741 AGAPSPAVPA STPGSAPVLP AVAVQTQTQT TSTEKDEEEE SQLQSTPASR DGAEEQQEEV1800
 1801 RAKPTPTKVP KSVSDKKRFF ESAMEDQHKP TQKTDKVFSF LSKDEVEKLR QEEERKIATL1860
 1861 RRDKNSRLLD AANDNIDKDA AQQRTKSNSN SSSGDDNDDS DQEEGIARGD SVDNAALGHF1920
 1921 DDAEDMRNPL DEIEAVFRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..708] PSI-BLAST 62.522879 The molecular structure of toll-like receptor 3 ligand binding domain
    2 View Details [709..814] deduced N/A No confident structure predictions are available.
    3 View Details [815..908] PSI-BLAST 22.045757 No description for 2g2lA was found.
    4 View Details [909..1010] deduced N/A No confident structure predictions are available.
    5 View Details [1011..1111] PSI-BLAST 22.154902 Solution structure of the first PDZ domain of scribble homolog protein (hScrib)
    6 View Details [1112..1230] deduced N/A No confident structure predictions are available.
    7 View Details [1231..1320] PSI-BLAST 26.69897 Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
    8 View Details [1321..1421] FFAS03 4.78 Solution structure of the alternatively spliced PDZ2 domain (PDZ2b) of PTP-Bas (hPTP1E)
    9 View Details [1422..1525] PSI-BLAST 24.0 Solution structure of the fourth PDZ domain of human scribble (KIAA0147 protein)
    10 View Details [1526..1639] deduced N/A No confident structure predictions are available.
    11 View Details [1640..1825] MSA 2.134995 View MSA. No confident structure predictions are available.
    12 View Details [1826..1939] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  0.566291652083235 bayes_pls_golite062009
  • protein binding
    		•  0.52823753548825 bayes_pls_golite062009
    6 No functions predicted.
    7
    Term Confidence Notes
  • binding
    		•  0.566291652083235 bayes_pls_golite062009
  • protein binding
    		•  0.52823753548825 bayes_pls_golite062009
    8
    Term Confidence Notes
  • binding
    		•  0.441071632281575 bayes_pls_golite062009
  • protein binding
    		•  0.340478308461139 bayes_pls_golite062009
    9
    Term Confidence Notes
  • binding
    		•  0.566291652083235 bayes_pls_golite062009
  • protein binding
    		•  0.52823753548825 bayes_pls_golite062009
    10 No functions predicted.
    11 No functions predicted.
    12 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle