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Protein Overview: mld-PB

General Information:
Name(s) found: mld-PB / FBpp0110312 [FlyBase]
Description(s) found:
Found 9 descriptions.
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  • The gene molting defective is referred to in FlyBase by the symbol Dmel\mld (CG34100, FBgn0083077). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20411385..20449621. It has the cytological map location 96A9-96A12. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: ecdysone biosynthetic process. 33 alleles are reported. The phenotype of these alleles is annotated with: ring gland. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1728 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: ecdysone biosynthetic process [IMP]
    Molecular Function: zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTMHIKRPF ICTLHIRHMY LCMFLPCINR DDGLPQEICR QCMAQFLMVA KFRRKCVRMQ  60
   61 QRLQDFAQEI SDRQTARQAK RQQKVQKKTH DRWLQLEPTS HEEQQPIRKR RMVSESDGDS 120
  121 TAAAAAAEAA TATATTPAKQ VRTDFESLPP PKPSPQQHRV RKYRTLSIDC EMERPAASIN 180
  181 ASSMPWKTKA ARKELSENWA SSCSTAVMSP NRQRSSTSSS EHMSDLSVGP CCGFESDSNP 240
  241 SSTSNSARRT VILVKQQSPE KTSPMYDLMP RRGRRPRKAP IYMPAKRQRR SLVRKEPLYR 300
  301 KAQPVNEENK KSDQKDIYPK ESRMEGLAPS CDEAIDSTSD APMEVASNVV QKKCDEICLN 360
  361 GLIDSRNQLG AMEMEPVNEM IASNGVDKEL TLSVQNNKET TSEEQIFEAT SVIKESVQPE 420
  421 QSAEDIQVRT EIESIANDIR AEADLVQSEE LTSSTETSES QPKAVEQLES MGKQESYALP 480
  481 QNMEAHESVQ QTQTVDESDS ADQREIIVSI PLEVLDENLQ RRLCVDPETE AANRQSADPK 540
  541 EFALRPDDVN NNENDENFCQ SATADSFNSA VALRTNKIEA TPPGGTDSDD TDTDEVPIVP 600
  601 SGPTPMDFMA EFAKHCANGI EQLKVTTPVP SPTPSDLVPL NDLEAKQKLE VEMNDVETTL 660
  661 NGILNEMQDQ HMYTPNCAHI DEFLTPADYA TLTEQESSVS SPPNPFEQSS VAEPKDEKPS 720
  721 ATEDPFDNSN FTNELIGFQN DIPCFENIET PEEGQNLHLE LTQFLRDLQP SQSDPPAGEQ 780
  781 VEKIEMETQP STVQMDVQSN LPVQAADTQP QNESANHSPF ESPISSPQVQ SQIELQMEPQ 840
  841 IETQMQPQIE TRMQHDVLSV QSPQNHQPQV QSHDQSQMQH QIPPQIEPQI EVQNQEQNTL 900
  901 QLVPQAQHQV VPHVQLQSQL VPHVQTQGTT TTVTYEQIYQ QHIVQQTVQQ SSNKMQVISL 960
  961 PSAGSETTRQ WQTQQSQQQQ QVQWSSVGGL EAIKSAPVES VAPTTTTYYI SASDLYPQQT1020
 1021 ETYTMLQPAS NESYVIEQVN HQQQHCQQQI QMSQQQHQRQ HQQQQAQQQQ QPIMILIQQP1080
 1081 EIQQPVASAS NPQQAPLHIY NAATSNDVHQ MQHTQRQQIR QQYQHQQYQR LQQPQQTRVV1140
 1141 QSHPVLGMPG ATSISTKVTP IPVTAARGRP LTLKCRFCHN GPRFSSSLEY SRHIIDLHPA1200
 1201 VAPFNCPHCP MAFAGRTKRS QHILSHHVVQ QYQCGQCSHV FPAQKALDVH IQRFHMTLKT1260
 1261 DPSGAVKVED VQLQITSERR PRGRPYKPRL QLQQHQLQPQ QKLQVQQHQQ QQKALQQLPQ1320
 1321 AQHHQQQQQP QLQQEVLQQV QQLQVQVQPQ QHQQHQQVLQ VQQPQQQPLM QPQSPHPSTV1380
 1381 EMQASPTTPR KILCCPDCED CTSGHSHANE QFEELQTLQA PPTVLTPPST IVSVPSPQPM1440
 1441 VYSQHITMPS PEQSEPDSTT TLRQYRKRGV IVGPQGPLHL ATPVASPSPS SSPSSSTVDH1500
 1501 IPPASPATPA SPAPPPSPAV ASTVQVSELR TSHHCLYCEE RFTNEISLKK HHQLAHGALT1560
 1561 TMPYVCTICK RGYRMRTALH RHMESHDVEG RPYECNICRV RFPRPSQLTL HKITVHLLSK1620
 1621 PHTCDECGKQ FGTESALKTH IKFHGAHMKT HLPLGVFRNE DAASKSPSNN NSHASSDKLE1680
 1681 NPATPIEETP LTPMSSGGHL YHSPDEYPNS VESCAGNSVA LESYATTP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] deduced N/A No confident structure predictions are available.
    2 View Details [236..331] deduced N/A No confident structure predictions are available.
    3 View Details [332..536] MSA 1.025979 View MSA. No confident structure predictions are available.
    4 View Details [537..756] deduced N/A No confident structure predictions are available.
    5 View Details [757..861] deduced N/A No confident structure predictions are available.
    6 View Details [862..1002] deduced N/A No confident structure predictions are available.
    7 View Details [1003..1070] MSA 1.362993 View MSA. No confident structure predictions are available.
    8 View Details [1071..1300] FFAS03 3.37 No description for 2i13A was found.
    9 View Details [1301..1421] PSI-BLAST 24.522879 Ying-yang 1 (yy1, zinc finger domain)
    10 View Details [1422..1547] PSI-BLAST 62.154902 No description for 2i13A was found.
    11 View Details [1548..1647] PSI-BLAST 23.522879 Five-finger GLI1
    12 View Details [1648..1728] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11
    Term Confidence Notes
  • binding
    		•  0.414217765611205 bayes_pls_golite062009
    12 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle