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View Structure Prediction Details

Protein: mld-PB
Organism: Drosophila melanogaster
Length: 1728 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mld-PB.

Description E-value Query
Range
Subject
Range
gi|68437121 - gi|68437121|ref|XP_694667.1| PREDICTED: similar to zinc finger protein 91 (HPF7, HTF10) [Danio rerio...
1150.0 [0..831] [1725..320]

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Predicted Domain #1
Region A:
Residues: [1-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTMHIKRPF ICTLHIRHMY LCMFLPCINR DDGLPQEICR QCMAQFLMVA KFRRKCVRMQ  60
   61 QRLQDFAQEI SDRQTARQAK RQQKVQKKTH DRWLQLEPTS HEEQQPIRKR RMVSESDGDS 120
  121 TAAAAAAEAA TATATTPAKQ VRTDFESLPP PKPSPQQHRV RKYRTLSIDC EMERPAASIN 180
  181 ASSMPWKTKA ARKELSENWA SSCSTAVMSP NRQRSSTSSS EHMSDLSVGP CCGFE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [236-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDSNPSSTSN SARRTVILVK QQSPEKTSPM YDLMPRRGRR PRKAPIYMPA KRQRRSLVRK  60
   61 EPLYRKAQPV NEENKKSDQK DIYPKESRME GLAPSC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [332-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEAIDSTSDA PMEVASNVVQ KKCDEICLNG LIDSRNQLGA MEMEPVNEMI ASNGVDKELT  60
   61 LSVQNNKETT SEEQIFEATS VIKESVQPEQ SAEDIQVRTE IESIANDIRA EADLVQSEEL 120
  121 TSSTETSESQ PKAVEQLESM GKQESYALPQ NMEAHESVQQ TQTVDESDSA DQREIIVSIP 180
  181 LEVLDENLQR RLCVDPETEA ANRQS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [537-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADPKEFALRP DDVNNNENDE NFCQSATADS FNSAVALRTN KIEATPPGGT DSDDTDTDEV  60
   61 PIVPSGPTPM DFMAEFAKHC ANGIEQLKVT TPVPSPTPSD LVPLNDLEAK QKLEVEMNDV 120
  121 ETTLNGILNE MQDQHMYTPN CAHIDEFLTP ADYATLTEQE SSVSSPPNPF EQSSVAEPKD 180
  181 EKPSATEDPF DNSNFTNELI GFQNDIPCFE NIETPEEGQN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [757-861]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHLELTQFLR DLQPSQSDPP AGEQVEKIEM ETQPSTVQMD VQSNLPVQAA DTQPQNESAN  60
   61 HSPFESPISS PQVQSQIELQ MEPQIETQMQ PQIETRMQHD VLSVQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [862-1002]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPQNHQPQVQ SHDQSQMQHQ IPPQIEPQIE VQNQEQNTLQ LVPQAQHQVV PHVQLQSQLV  60
   61 PHVQTQGTTT TVTYEQIYQQ HIVQQTVQQS SNKMQVISLP SAGSETTRQW QTQQSQQQQQ 120
  121 VQWSSVGGLE AIKSAPVESV A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1003-1070]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTTTTYYISA SDLYPQQTET YTMLQPASNE SYVIEQVNHQ QQHCQQQIQM SQQQHQRQHQ  60
   61 QQQAQQQQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1071-1300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPIMILIQQP EIQQPVASAS NPQQAPLHIY NAATSNDVHQ MQHTQRQQIR QQYQHQQYQR  60
   61 LQQPQQTRVV QSHPVLGMPG ATSISTKVTP IPVTAARGRP LTLKCRFCHN GPRFSSSLEY 120
  121 SRHIIDLHPA VAPFNCPHCP MAFAGRTKRS QHILSHHVVQ QYQCGQCSHV FPAQKALDVH 180
  181 IQRFHMTLKT DPSGAVKVED VQLQITSERR PRGRPYKPRL QLQQHQLQPQ 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.37
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #9
Region A:
Residues: [1301-1421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKLQVQQHQQ QQKALQQLPQ AQHHQQQQQP QLQQEVLQQV QQLQVQVQPQ QHQQHQQVLQ  60
   61 VQQPQQQPLM QPQSPHPSTV EMQASPTTPR KILCCPDCED CTSGHSHANE QFEELQTLQA 120
  121 P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1ubdC
Description: Ying-yang 1 (yy1, zinc finger domain)
Matching Structure (courtesy of the PDB):

Predicted Domain #10
Region A:
Residues: [1422-1547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTVLTPPSTI VSVPSPQPMV YSQHITMPSP EQSEPDSTTT LRQYRKRGVI VGPQGPLHLA  60
   61 TPVASPSPSS SPSSSTVDHI PPASPATPAS PAPPPSPAVA STVQVSELRT SHHCLYCEER 120
  121 FTNEIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.154902
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #11
Region A:
Residues: [1548-1647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKKHHQLAHG ALTTMPYVCT ICKRGYRMRT ALHRHMESHD VEGRPYECNI CRVRFPRPSQ  60
   61 LTLHKITVHL LSKPHTCDEC GKQFGTESAL KTHIKFHGAH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.414217765611205 bayes_pls_golite062009

Predicted Domain #12
Region A:
Residues: [1648-1728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTHLPLGVF RNEDAASKSP SNNNSHASSD KLENPATPIE ETPLTPMSSG GHLYHSPDEY  60
   61 PNSVESCAGN SVALESYATT P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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