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Protein Overview: Nup98-PA, FBpp03...

General Information:
Name(s) found: FBpp0306915 [FlyBase]
Nup98-PA / FBpp0083851 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • type=protein; loc=3R:complement(19600231..19600712,19600777..19601186,19601244..19602255,19602315..19602597,19602654..19602829,19603160..19603342,19603411..19603929,19604009..19606546,19606607..19606886); ID=FBpp0306915; name=Nup98-96-PD; parent=FBgn0039120,FBtr0334894; dbxref=FlyBase:FBpp0306915,FlyBase_Annotation_IDs:CG10198-PD,REFSEQ:NP_001262885,GB_protein:AGB96265; MD5=5ce1a9ef65cf6b8da3ab435921d47764; length=1960; release=r5.56; species=Dmel; [FlyBase]
  • The gene Nup98 is referred to in FlyBase by the symbol Dmel\Nup98 (CG10198, FBgn0039120). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19599947..19607366. It has the cytological map location 95B1-95B5. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1960 amino acids

    Gene Ontology:
    Cellular Component: nuclear pore [ISS]
    Biological Process: phagocytosis, engulfment [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGGAKPSFG ATPAATSFGG FSGTTTTTPF GQSAFGKPAA PAFGNTSTFA AQPAQQSLFG  60
   61 AAATPAQPAG GLFGANTSTG FGSTATAQPT AFGAFSQPQQ TSNIFGSTQT AASTSLFGQS 120
  121 TLPAFGAAKP TMTAFGQTAA AQPTGSLFGQ PAAATSTTGF GGFGTSAPTT TNVFGSGTAS 180
  181 AFAQPQATAV GASGVNTGTA VAKYQPTIGT DTLMKSGQAN SVNTKQHCIT AMKEFEGKSL 240
  241 EELRLEDYMC GRKGPQAGNA PGAFGFGAQV TQPAQPASGG LFGSTAQPST GLFGQTVTEN 300
  301 KSMFGTTAFG QQPATNNAFG AATQQNNFLQ KPFGATTTTP FAAPAADASN PFGAKPAFGQ 360
  361 GGSLFGQAPA TSAAPAFGQT NTGFGGFGTT AGATQQSTLF GATPAADPNK SAFGLGTAAS 420
  421 AATTGFGFGA PATSTAGGGL FGNKPATSFA APTFGATSTA STPFSNFGLN TSTAATGGGL 480
  481 FNSGLNKPAT SGFGGFGATS AAPLNFNAGN TGGSLFGNTA KPGGGLFGGG TTTLGGTGAA 540
  541 PTGGLFGGGT TSFGGVGGSL GGGGFGMGTN NSLTGGIMGA QPTLGIMTPS HQPIHQQILA 600
  601 RVTSPYGDSP IFKDLKLSSE ADATRATNPA AQQAVLDLTS NQYKISTSNN PAPMKVKALG 660
  661 STLNRKSLFD GLEEFDASVE GFNLKPSAKR LVIKPKVKSV EGGNPSSSIG SAPNTPQSRP 720
  721 KGATPNKERE SFSGAIPSEP LPPAGNSPGA TNGRESQDNG RRESWLHPNN LEKVRQHNIQ 780
  781 TGMDQGSPHN STLNELVPRK PLDTYRPSST VRLSVSTIPE NPFEDQSSTI ARRETFTSQQ 840
  841 ANESVLSNRS NEAEDSAANQ SRLAIEAAAA EAADDESHPT GIVLRRVGYY TIPSLDDLRS 900
  901 YLAEDGSCVV PNFTVGREGY GNVFFGKEMD VAGLNLDEIV HFRNKEIIIY PDDENKPPIG 960
  961 QGLNRDAQVT LDQVWPLDKT KHEAIKDPQR LLEMDWEGKL RRVCDKNDTR FIEYRPETGS1020
 1021 WVFRVKHFSK YGLGDSDEED ELPTDPKKAK IATLEAQQRA NAEKMTLNSL RQAQKISEDA1080
 1081 ARNLDPKALV AGVASGFRPM DDTAEFLLMD KTQFFQAGGN SDFSMFDPPR QRPTITSPTA1140
 1141 VLAQEMVGNE AHKMQLMKSS FFVEDNAPED EPMETTGRLL RHRKFFNVEP LVWKDGASES1200
 1201 SSQYDFEHPS PALPISSSVS EASLMCDAHY EETSSMATGS IVAAVKETKF EMPVTKAFKF1260
 1261 VCKPKVAPIK LRATTVPLPR SIAYEMRDNW IADLGFYKGR SFKLSFGPQN SLVLPSTYNN1320
 1321 MQNLKEFTGP SLPVSMVFAP RSATDLSPSV MQLVEFNMVK GNEGFRESII PHLEVQLNDC1380
 1381 LSVNVEGSEC PCIHPDSGTK LVSKHFSESL KQRNAGLKED YSVSVWSLLF ALWGDHDELV1440
 1441 DLEKNSHYMV MCRRNLLSEW LENTLLGKDL LSKKVSTHSY LEHMLDLLSC HRVNEACELA1500
 1501 FSYDDANLAL VLSQLSSGAV FRLLMEEQLF AWQQSKSDKY IDLERLKMYM LAAGAPMMQS1560
 1561 SHGAINLLEN KNWLTALALQ LWYFTAPTSS ITDALNAYND AFQAEECYAE PPKPSYRDAP1620
 1621 TDTKKPVYDL RYHLLQLHSK RMHSLEETLN PITHTADAMD FRLSWLLLQT LRALGYRHCS1680
 1681 PLTEARLSVD FASQLENEGL WQWGIFVLLH IKQQTQRERA VQQMLQRNVS VSAKVALYAE1740
 1741 ERFIVEELGI PMSWVDYAKA VKAGASGKHH LQAKYLLKAK HFATAHDVIF QHIAPDAIIN1800
 1801 GKMKYLHSLL IQFEDTEGSS IRVPNWANQG QIFLDFIDIS AKFKQIRSVT NIADINARWE1860
 1861 NLKPQLSELC SRISLLPCPT SKHRLCQSEI SQSLSCLVHG MCIVCPEMES STVLKVALER1920
 1921 LPLPQEFASK ELRIWLEELL DKIQNEPPFS ERQQPTMMEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..883] PSI-BLAST 72.522879 No description for 1y0fB was found.
    2 View Details [884..1031] PSI-BLAST 67.045757 C-terminal autoproteolytic domain of nucleoporin nup98
    3 View Details [1032..1275] deduced N/A No confident structure predictions are available.
    4 View Details [1276..1801] FFAS03 1.72 No description for 2pm6A was found.
    5 View Details [1802..1960] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.09735673847754 bayes_pls_golite062009
  • transporter activity
    		•  1.78222455998598 bayes_pls_golite062009
  • protein binding
    		•  0.99875460346231 bayes_pls_golite062009
  • structural constituent of nuclear pore
    		•  0.972136557180743 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.17

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle