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Protein Overview: GluRIIE-PB

General Information:
Name(s) found: GluRIIE-PB / FBpp0110134 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene Glutamate receptor IIE is referred to in FlyBase by the symbol Dmel\GluRIIE (CG31201, FBgn0051201). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16469876..16474436. It has the cytological map location 92F4. Based on sequence similarity, it is predicted to have molecular function</span>: kainate selective glutamate receptor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. 9 alleles are reported. The phenotype of these alleles is annotated with: neuromuscular junction. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 897 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: ion transport [IEA]
    Molecular Function: kainate selective glutamate receptor activity [ISS]
    extracellular-glutamate-gated ion channel activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFFNHFVILW SLFSIHISVN WAQYENFGGY DNYQSLESVP IGLLTDQNTE QMNIVFDHAI  60
   61 DVANQEVGTS LTSLKEEVNY GDAYQSYGKL CRMLETGIAG VFGPSSRHTA VHLMSICDAM 120
  121 DIPHIYSYMS ENAEGFNLHP HPADLAKALY SLITEFNWTR FIFLYESAEY LNILNELTTM 180
  181 LGKSGTVITV LRYDMQLNGN YKQVLRRVRK SVDNRIVVVG SSETMPEFLN QAQQVGIINE 240
  241 DYKYIIGNLD FHSFDLEEYK YSEANITGLR LFSPEKMAVK ELLMKLGYPT DQDEFRNGSC 300
  301 PITVEMALTY DAVQLFAQTL KNLPFKPMPQ NCSQRTESVR DDGSSFKNYM RTLRLTDRLL 360
  361 TGPIYFEGNV RKGYHLDVIE LQPSGIVKVG TWDEDRQYRP QRLAPTTAQF DSVDNSLANK 420
  421 TFIILLSVPN KPYAQLVETY KQLEGNSQYE GYGVDLIKEL ADKLGFNFTF VNGGNDYGSY 480
  481 NKSTNESTGM LREIMTGRAD LAITDLTITS EREQALDFTI PFMNLGIAIL YLKPQKATPE 540
  541 LFTFMDPFSE EVWWFLGFSF LGVSLSFFIL GRLSPSEWDN PYPCIEEPEE LENQFTLGNS 600
  601 IWFTTGALLQ QGSEIGPKAL STRTVASFWW FFTLIVVSSY TANLAAFLTI EKPQSLINSV 660
  661 DDLADNKDGV VYGAKKTGST RNFFMTSAEE RYKKMNKFMS ENPQYLTEDN MEGVNRVKTN 720
  721 THYAFLMEST SIEYNTKREC NLKKIGDALD EKGYGIAMRK DWPHRGKFNN ALLELQEQGV 780
  781 LEKMKNKWWN EVGTGICATK EDAPDATPLD MNNLEGVFFV LLVGSCCALL YGIISWVLFV 840
  841 MKKAHHYRVP LRDALKEEFQ FVIDFNNYVR VLKNSASIYS RSRQSSMSVA SVAQESQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..496] PSI-BLAST 43.69897 No description for 2e4uA was found.
    2 View Details [497..585] FFAS03 2.33 Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
    3 View Details [586..798] PSI-BLAST 30.39794 Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
    4 View Details [799..897] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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