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Protein Overview: p120ctn-PB

General Information:
Name(s) found: p120ctn-PB / FBpp0110405 [FlyBase]
Description(s) found:
Found 10 descriptions.
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  • The gene Adherens junction protein p120 is referred to in FlyBase by the symbol Dmel\p120ctn (CG17484, FBgn0260799). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:482798..496995. It has the cytological map location 41B1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: adherens junction maintenance; cell adhesion; compound eye morphogenesis. 15 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; stage 14 embryo; inter-ommatidial cell; embryonic leading edge cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 767 amino acids

    Gene Ontology:
    Cellular Component: adherens junction [IDA][IPI][ISS]
    centrosome [IDA]
    cytoplasm [IDA]
    Biological Process: compound eye morphogenesis [IGI][IMP]
    cell adhesion [IGI]
    adherens junction maintenance [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSTHINMDL SLTHEPANMQ SQFGSFQNYD QFSAAGYSST PLYITKPTGV GAITKVAPHC  60
   61 SQNKIETNST DNSIPDIENH PLATTVRYVQ AGQYEDTSEY GVAGLTCGID SEYTAEAVVP 120
  121 YCYTSDANYT GIQNTTSSIK PFSGRPFNDN INGAEAVADS QCRTFKSSAE FKLPQFAMSS 180
  181 INTVPQRLEE KDDYIEGSEN DICSTMRWRD PNLSEVISFL SNPSSAIKAN AAAYLQHLCY 240
  241 MDDPNKQRTR SLGGIPPLVR LLSYDSPEIH KNACGALRNL SYGRQNDENK RGIKNAGGIA 300
  301 ALVHLLCRSQ ETEVKELVTG VLWNMSSCED LKRSIIDEAL VAVVCSVIKP HSGWDAVCCG 360
  361 ETCFSTVFRN ASGVLRNVSS AGEHARGCLR NCEHLVECLL YVVRTSIEKN NIGNKTVENC 420
  421 VCILRNLSYR CQEVDDPNYD KHPFITPERV IPSSSKGENL GCFGTNKKKK EANNSDALNE 480
  481 YNISADYSKS SVTYNKLNKG YEQLWQPEVV QYYLSLLQSC SNPETLEAAA GAIQNLSACY 540
  541 WQPSIDIRAT VRKEKGLPIL VELLRMEVDR VVCAVATALR NLAIDQRNKE LIGKYAMRDL 600
  601 VQKLPSGNVQ HDQNTSDDTI TAVLATINEV IKKNPEFSRS LLDSGGIDRL MNITKRKEKY 660
  661 TSCVLKFASQ VLYTMWQHNE LRDVYKKNGW KEQDFVSKHF TAHNTPPSSP NNVNNTLNRP 720
  721 MASQGRTRYE DRTIQRGTST LYSANDSSGA VMSNESAMLS EMVRKQL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] PSI-BLAST 40.0 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
    2 View Details [199..703] PSI-BLAST 60.221849 Structure of the armadillo repeat domain of plakophilin 1
    3 View Details [704..767] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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