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Protein Overview: PCNA_MOUSE

General Information:
Name(s) found: PCNA_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74222336|dbj|BAE38082.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74219741|dbj|BAE40463.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74212037|dbj|BAE40183.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74191609|dbj|BAE30376.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74185524|dbj|BAE30230.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|7242171|ref|NP_035175.1| proliferating cell nuclear antigen [Mus musculus] [NCBI NR]
  • gi|53602|emb|CAA40938.1| proliferating cell nuclear antigen (DNA polymerase delta auxiliary protein) [Mus musculus] [NCBI NR]
  • pir||WMMS proliferating cell nuclear antigen - mouse [NCBI NR]
  • gi|26353220|dbj|BAC40240.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|16307587|gb|AAH10343.1| Proliferating cell nuclear antigen [Mus musculus] [NCBI NR]
  • gi|148696396|gb|EDL28343.1| mCG15182 [Mus musculus] [NCBI NR]
  • gi|13543223|gb|AAH05778.1| Proliferating cell nuclear antigen [Mus musculus] [NCBI NR]
  • gi|129695|sp|P17918.2|PCNA_MOUSE RecName: Full=Proliferating cell nuclear antigen; Short=PCNA; AltName: Full=Cyclin [NCBI NR]
  • gi|12849993|dbj|BAB28557.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|123229261|emb|CAM21508.1| proliferating cell nuclear antigen [Mus musculus] [NCBI NR]
  • Proliferating cell nuclear antigen OS=Mus musculus GN=Pcna PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):2-133900533 Proliferating cell nuclear antigen [hmr_yeast5_DM3-1_pombe.fasta]
  • proliferating cell nuclear antigen [HMR_022704-rand.fasta]
  • Proliferating cell nuclear antigen [ipi.MOUSE.v3.06.fasta]
  • proliferating cell nuclear antigen [Mus musculus]gi|13543223|gb|AAH05778.1| Proliferating cell nuclear antigen [Mus musculus]gi|16307587|gb|AAH10343.1| Proliferating cell nuclear antigen [Mus musculus]gi|319907|pir||WMMS proliferating cell nuclear anti [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Proliferating cell nuclear antigen [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_011045) proliferating cell nuclear antigen [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • proliferating cell nuclear antigen [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Proliferating cell nuclear antigen (PCNA) (Cyclin) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG15182 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Proliferating cell nuclear antigen [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • proliferating cell nuclear antigen (DNA polymerase delta auxiliary protein) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 PROLIFERATING CELL NUCLEAR ANTIGEN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Pcna Proliferating cell nuclear antigen [mouse-ipi-250309-contam.fasta]
  • IPI:IPI00113870.1|SWISS-PROT:P17918|TREMBL:Q542J9;Q91ZH2|ENSEMBL:ENSMUSP00000028817|REFSEQ:NP_035175|VEGA:OTTMUSP00000016567 Tax_Id=10090 Gene_Symbol=Pcna Proliferating cell nuclear antigen [ipi.MOUSE.fasta.20090209]
  • Proliferating cell nuclear antigen OS=Mus musculus GN=Pcna [011711_HMR.fasta]
  • sp|P17918|PCNA_MOUSE Proliferating cell nuclear antigen OS=Mus musculus GN=Pcna PE=1 SV=2 [uniprot.sptr.mouse.20130102]
  • tr|Q542J9|Q542J9_MOUSE DNA polymerase sliding clamp OS=Mus musculus GN=Pcna PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Proliferating cell nuclear antigen OS=Mus musculus GN=Pcna PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P17918, Proliferating cell nuclear antigen OS=Mus musculus GN=Pcna PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFEARLIQGS ILKKVLEALK DLINEACWDV SSGGVNLQSM DSSHVSLVQL TLRSEGFDTY  60
   61 RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD 120
  121 LDVEQLGIPE QEYSCVIKMP SGEFARICRD LSHIGDAVVI SCAKNGVKFS ASGELGNGNI 180
  181 KLSQTSNVDK EEEAVTIEMN EPVHLTFALR YLNFFTKATP LSPTVTLSMS ADVPLVVEYK 240
  241 IADMGHLKYY LAPKIEDEEA S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] PSI-BLAST 77.39794 Prolifirating cell nuclear antigen (PCNA)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA polymerase processivity factor activity
    		•  9.9878881203193 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  5.01426276108174 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.9656505576274 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  3.23598180825386 bayes_pls_golite062009
  • mismatched DNA binding
    		•  2.75713709757781 bayes_pls_golite062009
  • DNA insertion or deletion binding
    		•  2.48680473192192 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32553487472442 bayes_pls_golite062009
  • DNA binding
    		•  2.24518789437215 bayes_pls_golite062009
  • binding
    		•  1.88302251910664 bayes_pls_golite062009
  • dinucleotide insertion or deletion binding
    		•  1.68153838099672 bayes_pls_golite062009
  • mismatch repair complex binding
    		•  1.6296761041903 bayes_pls_golite062009
  • MutLalpha complex binding
    		•  1.21442872292245 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.14392061238362 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.785542777582287 bayes_pls_golite062009
  • catalytic activity
    		•  0.48077242755678 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.457118392479642 bayes_pls_golite062009
  • protein binding
    		•  0.452894757163315 bayes_pls_golite062009
  • purine-specific mismatch base pair DNA N-glycosylase activity
    		•  0.408841404605319 bayes_pls_golite062009
  • mismatch base pair DNA N-glycosylase activity
    		•  0.387975438046246 bayes_pls_golite062009
  • transferase activity
    		•  0.345371754708312 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle