General Information: |
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Name(s) found: |
GLI1_MOUSE
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Mus musculus |
Length: | 1111 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[IDA]
cytoplasm [IDA][IGI] cilium [IDA] intracellular [IEA] |
Biological Process: |
smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation
[IGI]
transcription [IEA] multicellular organismal development [IEA] signal transduction [TAS] spermatogenesis [IDA] notochord regression [IGI] positive regulation of transcription [IDA] smoothened signaling pathway [IDA][IGI] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] proximal/distal pattern formation [IGI] cerebellar cortex morphogenesis [IGI] pituitary gland development [IGI] dorsal/ventral pattern formation [IGI] ventral midline development [IGI] positive regulation of transcription, DNA-dependent [IDA] cell differentiation [IEA] lung development [IGI] |
Molecular Function: |
nucleic acid binding
[IEA]
DNA binding [UNKNOWN][IDA] zinc ion binding [IEA] protein binding [IPI] metal ion binding [IEA] RNA polymerase II transcription factor activity, enhancer binding [IDA] transcription activator activity [IDA] chromatin binding [IDA] microtubule binding [IDA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MFNPMTPPQV NSYSEPCCLR PLHSQGVPSM GTEGLSGLPF CHQANFMSGS QGYGAARETS 60 61 SCTEGSLFPP PPPPRSSVKL TKKRALSISP LSDASLDLQT VIRTSPSSLV AFINSRCTSP 120 121 GGSYGHLSIG TMSPSLGFPP QMSHQKGTSP PYGVQPCVPH DSTRGSMMLH PQARGPRATC 180 181 QLKSELDMMV GKCPEDPLEG DMSSPNSTGI QDHLLGMLDG REDLEREEKP EPESVYETDC 240 241 RWDGCSQEFD SQEQLVHHIN SEHIHGERKE FVCHWGGCSR ELRPFKAQYM LVVHMRRHTG 300 301 EKPHKCTFEG CRKSYSRLEN LKTHLRSHTG EKPYMCEQEG CSKAFSNASD RAKHQNRTHS 360 361 NEKPYVCKLP GCTKRYTDPS SLRKHVKTVH GPDAHVTKRH RGDGPLPRAQ PLSTVEPKRE 420 421 REGGSGREES RLTVPESAMP QQSPGAQSSC SSDHSPAGSA ANTDSGVEMA GNAGGSTEDL 480 481 SSLDEGPCVS ATGLSTLRRL ENLRLDQLHQ LRPIGSRGLK LPSLTHAGAP VSRRLGPPVS 540 541 LDRRSSSSSS MSSAYTVSRR SSLASPFPPG TPPENGASSL PGLTPAQHYM LRARYASARG 600 601 SGTPPTAAHS LDRMGGLSVP PWRSRTEYPG YNPNAGVTRR ASDPARAADH PAPARVQRFK 660 661 SLGCVHTPPS VATGRNFDPH HPTSVYSPQP PSITENVAMD TRGLQEEPEV GTSVMGNGLN 720 721 PYMDFSSTDT LGYGGPEGTA AEPYEARGPG SLPLGPGPPT NYGPGHCAQQ VSYPDPTPEN 780 781 WGEFPSHAGV YPSNKAPGAA YSQCPRLEHY GQVQVKPEQG CPVGSDSTGL APCLNAHPSE 840 841 GSPGPQPLFS HHPQLPQPQY PQSGPYPQPP HGYLSTEPRL GLNFNPSSSH STGQLKAQLV 900 901 CNYVQSQQEL LWEGRNRGGL PNQELPYQSP KFLGGSQVSQ SPAKTPAAAA AAYGSGFAPA 960 961 SANHKSGSYP APSPCHETFT VGVNRPSHRP AAPPRLLPPL SPCYGPLKVG DTNPSCGHPE1020 1021 VGRLGAGPAL YPPPEGQVCN ALDSLDLDNT QLDFVAILDE AQGLSPPLSH EQGDSSKNTP1080 1081 SPSGPPNMAV GNMSVLLGSL PGETQFLNSS A |
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.96 |
Source: Reynolds et al. (2008)