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Protein Overview: RASAL2

General Information:
Name(s) found: RASAL2 [HGNC (HUGO)]
Description(s) found:
Found 29 descriptions.
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  • RAS protein activator like 2 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 1139 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTPEVPAER SPRRRSISGT STSEKPNSMD TANTSPFKVP GFFSKRLKGS IKRTKSQSKL  60
   61 DRNTSFRLPS LRSTDDRSRG LPKLKESRSH ESLLSPCSTV ECLDLGRGEP VSVKPLHSSI 120
  121 LGQDFCFEVT YLSGSKCFSC NSASERDKWM ENLRRTVQPN KDNCRRAENV LRLWIIEAKD 180
  181 LAPKKKYFCE LCLDDTLFAR TTSKTKADNI FWGEHFEFFS LPPLHSITVH IYKDVEKKKK 240
  241 KDKNNYVGLV NIPTASVTGR QFVEKWYPVS TPTPNKGKTG GPSIRIKSRF QTITILPMEQ 300
  301 YKEFAEFVTS NYTMLCSVLE PVISVRNKEE LACALVHILQ STGRAKDFLT DLVMSEVDRC 360
  361 GEHDVLIFRE NTIATKSIEE YLKLVGQQYL HDALGEFIKA LYESDENCEV DPSKCSSSEL 420
  421 IDHQSNLKMC CELAFCKIIN SYCVFPRELK EVFASWKQQC LNRGKQDISE RLISASLFLR 480
  481 FLCPAIMSPS LFNLMQEYPD DRTSRTLTLI AKVIQNLANF AKFGNKEEYM AFMNDFLEHE 540
  541 WGGMKRFLLE ISNPDTISNT PGFDGYIDLG RELSVLHSLL WEVVSQLDKG ENSFLQATVA 600
  601 KLGPLPRVLA DITKSLTNPT PIQQQLRRFT EHNSSPNVSG SLSSGLQKIF EDPTDSDLHK 660
  661 LKSPSQDNTD SYFRGKTLLL VQQASSQSMT YSEKDERESS LPNGRSVSLM DLQDTHAAQV 720
  721 EHASVMLDVP IRLTGSQLSI TQVASIKQLR ETQSTPQSAP QVRRPLHPAL NQPGGLQPLS 780
  781 FQNPVYHLNN PIPAMPKASI DSSLENLSTA SSRSQSNSED FKLSGPSNSS MEDFTKRSTQ 840
  841 SEDFSRRHTV PDRHIPLALP RQNSTGQAQI RKVDQGGLGA RAKAPPSLPH SASLRSTGSM 900
  901 SVVSAALVAE PVQNGSRSRQ QSSSSRESPV PKVRAIQRQQ TQQVQSPVDS ATMSPVERTA 960
  961 AWVLNNGQYE EDVEETEQNL DEAKHAEKYE QEITKLKERL RVSSRRLEEY ERRLLVQEQQ1020
 1021 MQKLLLEYKA RLEDSEERLR RQQEEKDSQM KSIISRLMAV EEELKKDHAE MQAVIDAKQK1080
 1081 IIDAQEKRIV SLDSANTRLM SALTQVKERY SMQVRNGISP TNPTKLSITE NGEFKNSSC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC145 from april 2005 Okada, M., et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] deduced N/A No confident structure predictions are available.
    2 View Details [81..159] PSI-BLAST 3.522879 GEF of intersectin
    3 View Details [160..274] PSI-BLAST 20.522879 No description for 2enpA was found.
    4 View Details [275..371] PSI-BLAST 28.69897 RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP
    5 View Details [372..911] PSI-BLAST 22.221849 Heavy meromyosin subfragment
    6 View Details [912..1139] PSI-BLAST 6.154902 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • GTPase regulator activity
    		•  2.93605169651831 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.90950506941724 bayes_pls_golite062009
  • GTPase activator activity
    		•  2.89158618018952 bayes_pls_golite062009
  • enzyme activator activity
    		•  2.65585309928131 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.60801221683922 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  2.49898939104391 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  2.47392481225609 bayes_pls_golite062009
  • Rho GTPase activator activity
    		•  2.25477524109807 bayes_pls_golite062009
  • binding
    		•  1.36633307106754 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  1.03094355400281 bayes_pls_golite062009
  • protein binding
    		•  0.959391682784807 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle