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Protein Overview: NDUFV1

General Information:
Name(s) found: NDUFV1 [HGNC (HUGO)]
Description(s) found:
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  • pir||JE0092 NADH2 dehydrogenase (ubiquinone) (EC 1.6.5.3) flavoprotein 1 precursor [validated] - human [NCBI NR]
  • gi|5138912|gb|AAD40373.1| 51kDa subunit of NADH dehydrogenase [Homo sapiens] [NCBI NR]
  • gi|48145595|emb|CAG33020.1| NDUFV1 [Homo sapiens] [NCBI NR]
  • gi|3136152|gb|AAC39750.1| NADH:ubiquinone dehydrogenase 51 kDa subunit [Homo sapiens] [NCBI NR]
  • gi|3095113|gb|AAC39722.1| NADH:ubiquinone dehydrogenase 51 kDa subunit [Homo sapiens] [NCBI NR]
  • gi|20455501|sp|P49821.4|NDUV1_HUMAN RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; AltName: Full=NADH-ubiquinone oxidoreductase 51 kDa subunit; AltName: Full=Complex I-51kD; Short=CI-51kD; AltName: Full=NADH dehydrogenase fla [NCBI NR]
  • gi|20149568|ref|NP_009034.2| NADH dehydrogenase ubiquinone flavoprotein 1 precursor [Homo sapiens] [NCBI NR]
  • gi|15990511|gb|AAH15645.1| NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Homo sapiens] [NCBI NR]
  • gi|119595062|gb|EAW74656.1| NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa, isoform CRA_d [Homo sapiens] [NCBI NR]
  • gi|119595061|gb|EAW74655.1| NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa, isoform CRA_d [Homo sapiens] [NCBI NR]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [HGNC (HUGO)]
  • (P49821) NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-51KD) (CI-51KD) (NADH dehydrogenase flavoprotein 1) [Swiss-Prot]
  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens GN=NDUFV1 PE=1 SV=4 [Swiss-Prot]
  • Splice isoform 1 of P49821 [hmr_yeast5_DM3-1_pombe.fasta]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; NADH dehydrogenase (ubiquinone) flavoprotein 1 (51kD) [HMR_022704.fasta]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Homo sapiens]gi|15990511|gb|AAH15645.1| NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Homo sapiens]gi|5138912|gb|AAD40373.1| 51kDa subunit of NADH dehydrogenase [Homo sapiens]gi|7427772|pi [nrdb_11152004_Chlamydomonas]
  • NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor (Complex I-51KD) (CI-51KD) (NADH dehydrogenase flavoprotein 1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_007103) NADH dehydrogenase (ubiquinone) flavoprotein 1 (51kD) [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; NADH dehydrogenase (ubiquinone) flavoprotein 1 (51kD) [Homo sapiens] [HumanGallus06162005.fasta]
  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor (NADH-ubiquinone oxidoreductase 51 kDa subunit) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa, isoform CRA_d [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • NDUFV1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • 51kDa subunit of NADH dehydrogenase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • NADH:ubiquinone dehydrogenase 51 kDa subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF NADH-UBIQUINONE OXIDOREDUCTASE 51 KDA SUBUNIT, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NDUFV1 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [human-ipi-250309-contam.fasta]
  • NADH dehydrogenase ubiquinone flavoprotein 1 precursor [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • NADH dehydrogenase ubiquinone flavoprotein 1 isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta]
  • IPI:IPI00028520.2|SWISS-PROT:P49821-1|TREMBL:Q53G70;Q6IBR3|ENSEMBL:ENSP00000322450|REFSEQ:NP_009034|H-INV:HIT000001839 Tax_Id=9606 Gene_Symbol=NDUFV1 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=NDUFV1 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor ENSG00000167792 IPI00028520 IPI00221298 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NDUFV1 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P49821;O60924;O60940;Q16104;Q6IBR3;Q96BF8;Q96HS7; RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; AltName: Full=NADH-ubiquinone oxidoreductase 51 kDa subunit; AltName: Full=Complex I-51kD; AltName: Full=NADH dehydrogenase flavoprotein 1; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens GN=NDUFV1 [011711_HMR.fasta]
  • IPI:IPI00028520.2|SWISS-PROT:P49821-1|TREMBL:Q53G70|ENSEMBL:ENSP00000322450|REFSEQ:NP_009034|H-INV:HIT000001839 Tax_Id=9606 Gene_Symbol=NDUFV1 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=NDUFV1 Synonyms=CI-51K|CI51KD|FLJ59059|UQOR1 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform 1 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00028520.2|SWISS-PROT:P49821-1|TREMBL:E5KNH5;Q53G70|ENSEMBL:ENSP00000322450|REFSEQ:NP_009034|H-INV:HIT000001839|VEGA:OTTHUMP00000232178 Tax_Id=9606 Gene_Symbol=NDUFV1 Isoform 1 of NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [ipi.HUMAN.20110912.fasta]
  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial GN=NDUFV1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1 OS=Homo sapiens GN=NDUFV1 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 464 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATRRLLGW SLPARVSVRF SGDTTAPKKT SFGSLKDEDR IFTNLYGRHD WRLKGSLSRG  60
   61 DWYKTKEILL KGPDWILGEI KTSGLRGRGG AGFPTGLKWS FMNKPSDGRP KYLVVNADEG 120
  121 EPGTCKDREI LRHDPHKLLE GCLVGGRAMG ARAAYIYIRG EFYNEASNLQ VAIREAYEAG 180
  181 LIGKNACGSG YDFDVFVVRG AGAYICGEET ALIESIEGKQ GKPRLKPPFP ADVGVFGCPT 240
  241 TVANVETVAV SPTICRRGGT WFAGFGRERN SGTKLFNISG HVNHPCTVEE EMSVPLKELI 300
  301 EKHAGGVTGG WDNLLAVIPG GSSTPLIPKS VCETVLMDFD ALVQAQTGLG TAAVIVMDRS 360
  361 TDIVKAIARL IEFYKHESCG QCTPCREGVD WMNKVMARFV RGDARPAEID SLWEISKQIE 420
  421 GHTICALGDG AAWPVQGLIR HFRPELEERM QRFAQQHQAR QAAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..464] PSI-BLAST 153.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.4136491947011 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.443012098477 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.1743193111446 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  11.5132141901667 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  10.8948060301507 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.75377893144873 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  3.21486196088149 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  2.15499718507114 bayes_pls_golite062009
  • electron carrier activity
    		•  1.50427278540084 bayes_pls_golite062009
  • catalytic activity
    		•  1.46362311772849 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.25645944988955 bayes_pls_golite062009
  • metal cluster binding
    		•  1.25645944988955 bayes_pls_golite062009
  • binding
    		•  1.25265721111105 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor
    		•  0.530794334701446 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.471058486160512 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  0.281674499766589 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  0.281674499766589 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.53

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle