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View Structure Prediction Details

Protein: NDUFV1
Organism: Homo sapiens
Length: 464 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NDUFV1.

Description E-value Query
Range
Subject
Range
NDUV1_MOUSE - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Mus musculus GN=Ndufv1 PE=1 SV=1
0.0 [1..464] [1..464]
gi|73982785 - gi|73982785|ref|XP_864381.1| PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 5...
0.0 [1..464] [1..457]
NDUV1_PANTR - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Pan troglodytes GN=NDUFV1 PE=2 SV=1
0.0 [1..453] [1..453]
gi|111661793 - gi|111661793|gb|ABH12158.1| mitochondrial complex I subunit NDUFV1 [Gorilla gorilla]
NDUV1_GORGO - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Gorilla gorilla gorilla GN=NDUFV1 P...
0.0 [1..453] [1..453]
NDUV1_PONPY - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Pongo pygmaeus GN=NDUFV1 PE=2 SV=1
NDUV1_PONAB - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Pongo abelii GN=NDUFV1 PE=2 SV=1
0.0 [1..453] [1..453]
gi|62897683 - gi|62897683|dbj|BAD96781.1| NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa variant [Homo sapi...
0.0 [1..453] [1..453]
NDUV1_BOVIN - NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Bos taurus GN=NDUFV1 PE=1 SV=2
0.0 [1..450] [1..450]

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Predicted Domain #1
Region A:
Residues: [1-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATRRLLGW SLPARVSVRF SGDTTAPKKT SFGSLKDEDR IFTNLYGRHD WRLKGSLSRG  60
   61 DWYKTKEILL KGPDWILGEI KTSGLRGRGG AGFPTGLKWS FMNKPSDGRP KYLVVNADEG 120
  121 EPGTCKDREI LRHDPHKLLE GCLVGGRAMG ARAAYIYIRG EFYNEASNLQ VAIREAYEAG 180
  181 LIGKNACGSG YDFDVFVVRG AGAYICGEET ALIESIEGKQ GKPRLKPPFP ADVGVFGCPT 240
  241 TVANVETVAV SPTICRRGGT WFAGFGRERN SGTKLFNISG HVNHPCTVEE EMSVPLKELI 300
  301 EKHAGGVTGG WDNLLAVIPG GSSTPLIPKS VCETVLMDFD ALVQAQTGLG TAAVIVMDRS 360
  361 TDIVKAIARL IEFYKHESCG QCTPCREGVD WMNKVMARFV RGDARPAEID SLWEISKQIE 420
  421 GHTICALGDG AAWPVQGLIR HFRPELEERM QRFAQQHQAR QAAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 153.0
Match: 2fug1
Description: Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
NADH dehydrogenase activity 13.4136491947011 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 12.443012098477 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 12.1743193111446 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 11.5132141901667 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 10.8948060301507 bayes_pls_golite062009
oxidoreductase activity 6.75377893144873 bayes_pls_golite062009
formate dehydrogenase activity 3.21486196088149 bayes_pls_golite062009
4 iron, 4 sulfur cluster binding 2.15499718507114 bayes_pls_golite062009
electron carrier activity 1.50427278540084 bayes_pls_golite062009
catalytic activity 1.46362311772849 bayes_pls_golite062009
iron-sulfur cluster binding 1.25645944988955 bayes_pls_golite062009
metal cluster binding 1.25645944988955 bayes_pls_golite062009
binding 1.25265721111105 bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor 0.530794334701446 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.471058486160512 bayes_pls_golite062009
ferredoxin hydrogenase activity 0.281674499766589 bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor 0.281674499766589 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle