Protein Overview: NDUFV1

General Information:
Name(s) found:	NDUFV1 [HGNC (HUGO)]
Description(s) found: Found 44 descriptions. SHOW ALL	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [HGNC (HUGO)]
Organism:	Homo sapiens
Length:	464 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATRRLLGW SLPARVSVRF SGDTTAPKKT SFGSLKDEDR IFTNLYGRHD WRLKGSLSRG  60
   61 DWYKTKEILL KGPDWILGEI KTSGLRGRGG AGFPTGLKWS FMNKPSDGRP KYLVVNADEG 120
  121 EPGTCKDREI LRHDPHKLLE GCLVGGRAMG ARAAYIYIRG EFYNEASNLQ VAIREAYEAG 180
  181 LIGKNACGSG YDFDVFVVRG AGAYICGEET ALIESIEGKQ GKPRLKPPFP ADVGVFGCPT 240
  241 TVANVETVAV SPTICRRGGT WFAGFGRERN SGTKLFNISG HVNHPCTVEE EMSVPLKELI 300
  301 EKHAGGVTGG WDNLLAVIPG GSSTPLIPKS VCETVLMDFD ALVQAQTGLG TAAVIVMDRS 360
  361 TDIVKAIARL IEFYKHESCG QCTPCREGVD WMNKVMARFV RGDARPAEID SLWEISKQIE 420
  421 GHTICALGDG AAWPVQGLIR HFRPELEERM QRFAQQHQAR QAAS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..464]	PSI-BLAST	153.0	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
NADH dehydrogenase activity	13.4136491947011	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	12.443012098477	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	12.1743193111446	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	11.5132141901667	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	10.8948060301507	bayes_pls_golite062009
oxidoreductase activity	6.75377893144873	bayes_pls_golite062009
formate dehydrogenase activity	3.21486196088149	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	2.15499718507114	bayes_pls_golite062009
electron carrier activity	1.50427278540084	bayes_pls_golite062009
catalytic activity	1.46362311772849	bayes_pls_golite062009
iron-sulfur cluster binding	1.25645944988955	bayes_pls_golite062009
metal cluster binding	1.25645944988955	bayes_pls_golite062009
binding	1.25265721111105	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor	0.530794334701446	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.471058486160512	bayes_pls_golite062009
ferredoxin hydrogenase activity	0.281674499766589	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	0.281674499766589	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.53

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle