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Protein Overview: NMNAT1

General Information:
Name(s) found: NMNAT1 [HGNC (HUGO)]
Description(s) found:
Found 75 descriptions.
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  • nicotinamide nucleotide adenylyltransferase 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 279 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENSEKTEVV LLACGSFNPI TNMHLRLFEL AKDYMNGTGR YTVVKGIISP VGDAYKKKGL  60
   61 IPAYHRVIMA ELATKNSKWV EVDTWESLQK EWKETLKVLR HHQEKLEASD CDHQQNSPTL 120
  121 ERPGRKRKWT ETQDSSQKKS LEPKTKAVPK VKLLCGADLL ESFAVPNLWK SEDITQIVAN 180
  181 YGLICVTRAG NDAQKFIYES DVLWKHRSNI HVVNEWIAND ISSTKIRRAL RRGQSIRYLV 240
  241 PDLVQEYIEK HNLYSSESED RNAGVILAPL QRNTAEAKT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. NMNAT1 gi|112491310

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..279] PSI-BLAST 77.0 Nicotinamide mononucleotide (NMN) adenylyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nicotinate-nucleotide adenylyltransferase activity
    		•  2.94996967804011 bayes_pls_golite062009
  • nicotinamide-nucleotide adenylyltransferase activity
    		•  2.8149071156304 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  2.54008423253828 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  2.54008423253828 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  2.52910114154477 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • ligase activity
    		•  1.92894388839884 bayes_pls_golite062009
  • binding
    		•  1.11291710031577 bayes_pls_golite062009
  • adenylyltransferase activity
    		•  1.08055019963499 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.623161608923414 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.564359271862248 bayes_pls_golite062009
  • pantetheine-phosphate adenylyltransferase activity
    		•  0.454904507512502 bayes_pls_golite062009
  • pantoate-beta-alanine ligase activity
    		•  0.282286652169846 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle