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Protein Overview: NUDT2

General Information:
Name(s) found: NUDT2 [HGNC (HUGO)]
Description(s) found:
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  • gi|55958893|emb|CAI15964.1| nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Homo sapiens] [NCBI NR]
  • gi|4502125|ref|NP_001152.1| nudix-type motif 2 [Homo sapiens] [NCBI NR]
  • gi|22219467|ref|NP_671702.1| nudix-type motif 2 [Homo sapiens] [NCBI NR]
  • gi|22219465|ref|NP_671701.1| nudix-type motif 2 [Homo sapiens] [NCBI NR]
  • pir||S60111 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) - human [NCBI NR]
  • gi|1703326|sp|P50583.3|AP4A_HUMAN RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Short=Diadenosine tetraphosphatase; Short=Ap4A hydrolase; Short=Ap4Aase; AltN [NCBI NR]
  • gi|13436251|gb|AAH04926.1| Nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Homo sapiens] [NCBI NR]
  • gi|119578867|gb|EAW58463.1| nudix (nucleoside diphosphate linked moiety X)-type motif 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119578866|gb|EAW58462.1| nudix (nucleoside diphosphate linked moiety X)-type motif 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119578865|gb|EAW58461.1| nudix (nucleoside diphosphate linked moiety X)-type motif 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|1050961|gb|AAC50277.1| diadenosine tetraphosphatase [NCBI NR]
  • nudix (nucleoside diphosphate linked moiety X)-type motif 2 [HGNC (HUGO)]
  • Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Homo sapiens GN=NUDT2 PE=1 SV=3 [Swiss-Prot]
  • nudix-type motif 2 [hmr_yeast5_DM3-1_pombe.fasta]
  • nudix-type motif 2; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [HMR_022704.fasta]
  • nudix-type motif 2; Ap4A hydrolase 1; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [Human2242005.fasta]
  • PREDICTED: similar to Bis(5-nucleosyl)-tetraphosphatase [Asymmetrical] (Diadenosine 5,5-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4AASE) [Pan troglodytes]gi|22219467|ref|NP_671702.1| nudix-type motif [nrdb_11152004_Chlamydomonas]
  • Bis(5'-nucleosyl)-tetraphosphatase [Asymmetrical] (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • (NM_147172) nudix-type motif 2; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • (NM_147173) nudix-type motif 2; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • (NM_001161) nudix-type motif 2; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • nudix-type motif 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Nudix-type motif 2 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • nudix-type motif 2; Ap4A hydrolase 1; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [Homo sapiens] [HumanGallus06162005.fasta]
  • nudix-type motif 2; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); diadenosine tetraphosphatase; NUDIX motif 2 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Diadenosine tetraphosphatase) (Ap4A hydrolase) (Ap4Aase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • nudix (nucleoside diphosphate linked moiety X)-type motif 2, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • diadenosine tetraphosphatase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 NUDIX-TYPE MOTIF 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NUDT2 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [human-ipi-250309-contam.fasta]
  • IPI:IPI00221231.3|SWISS-PROT:P50583|ENSEMBL:ENSP00000338397;ENSP00000344187;ENSP00000368451;ENSP00000368452;ENSP00000368455;ENSP00000384512|REFSEQ:NP_001152;NP_671701;NP_671702|H-INV:HIT000219031|VEGA:OTTHUMP00000021256;OTTHUMP00000021257;OTTHUMP000000212 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Bis(5'-nucleosyl)-tetraphosphatase [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=NUDT2 Bis(5'-nucleosyl)-tetraphosphatase ENSG00000164978 IPI00221231 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NUDT2 Bis(5'-nucleosyl)-tetraphosphatase [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • bis(5'-nucleosyl)-tetraphosphatase [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P50583;Q5T589; RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; AltName: Full=Nucleoside diphosphate-linked moiety X motif 2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Homo sapiens GN=NUDT2 [011711_HMR.fasta]
  • IPI:IPI00221231.3|SWISS-PROT:P50583|TREMBL:D3DRM0|ENSEMBL:ENSP00000338397;ENSP00000344187;ENSP00000368451;ENSP00000368452;ENSP00000368455;ENSP00000384512|REFSEQ:NP_001152;NP_671701;NP_671702|H-INV:HIT000219031|VEGA:OTTHUMP00000021256;OTTHUMP00000021257;OTTHUMP00000021258;OTTHUMP00000021259 Tax_Id=9606 Gene_Symbol=NUDT2 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=NUDT2 Synonyms=APAH1|MGC10404 bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00221231.3|SWISS-PROT:P50583|ENSEMBL:ENSP00000338397;ENSP00000344187;ENSP00000368451;ENSP00000368452;ENSP00000368455|REFSEQ:NP_001152;NP_671701;NP_671702|H-INV:HIT000219031|VEGA:OTTHUMP00000021256;OTTHUMP00000021257;OTTHUMP00000021258;OTTHUMP00000021259 Tax_Id=9606 Gene_Symbol=NUDT2 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [ipi.HUMAN.20110912.fasta]
  • Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] GN=NUDT2 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 147 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ  60
   61 EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE 120
  121 EACQLAQFKE MKAALQEGHQ FLCSIEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 26.0 Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.49075808737475 bayes_pls_golite062009
  • protein binding
    		•  0.909777539571952 bayes_pls_golite062009
  • binding
    		•  0.496457788697257 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle