YRC Public Data Repository - Protein Structure Prediction

Protein:	NUDT2
Organism:	Homo sapiens
Length:	147 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUDT2.

Description	E-value	Query Range	Subject Range
gi\|13384960, gi\|... - ref\|NP_079815.1\| nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Mus musculus], gi\|128...	3.0E-25	[1..147]	[1..147]
AP4A_PIG - Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Sus scrofa GN=NUDT2 PE=2 SV=3	4.0E-25	[1..147]	[1..147]
gi\|60826381, gi\|... - gi\|61365401\|gb\|AAX42702.1\| nudix-type motif 2 [synthetic construct], gi\|60826381\|gb\|AAX36755.1\| nudi...	4.0E-25	[1..147]	[1..147]
AP4A_RAT - Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Rattus norvegicus GN=Nudt2 PE=2 SV=3	5.0E-25	[1..147]	[1..147]
gi\|109111196 - gi\|109111196\|ref\|XP_001098004.1\| PREDICTED: nudix (nucleoside diphosphate linked moiety X)-type moti...	8.0E-25	[1..147]	[1..147]
gi\|159163625, gi... - gi\|58177585\|pdb\|1XSC\|A Chain A, Structure Of The Nudix Enzyme Ap4a Hydrolase From Homo Sapiens (E63a...	1.0E-24	[1..147]	[6..152]
gi\|57093665 - gi\|57093665\|ref\|XP_531977.1\| PREDICTED: similar to Bis(5-nucleosyl)-tetraphosphatase [Asymmetrical] ...	5.0E-24	[1..147]	[1..147]

Back

Predicted Domain #1

Region A:
Residues: [1-147]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRACGLII FRRCLIPKVD NNAIEFLLLQ ASDGIHHWTP PKGHVEPGED DLETALRETQ  60
   61 EEAGIEAGQL TIIEGFKREL NYVARNKPKT VIYWLAEVKD YDVEIRLSHE HQAYRWLGLE 120
  121 EACQLAQFKE MKAALQEGHQ FLCSIEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.0
Match:	1xsaA
Description:	Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.49075808737475	bayes_pls_golite062009
protein binding	0.909777539571952	bayes_pls_golite062009
binding	0.496457788697257	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: